(data stored in ACNUC7421 zone)

SWISSPROT: Q750W1_ASHGO

ID   Q750W1_ASHGO            Unreviewed;       898 AA.
AC   Q750W1;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 2.
DT   11-DEC-2019, entry version 98.
DE   SubName: Full=AGL172Wp {ECO:0000313|EMBL:AAS54319.2};
GN   ORFNames=AGOS_AGL172W {ECO:0000313|EMBL:AAS54319.2};
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811 {ECO:0000313|EMBL:AAS54319.2, ECO:0000313|Proteomes:UP000000591};
RN   [1] {ECO:0000313|EMBL:AAS54319.2, ECO:0000313|Proteomes:UP000000591}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Pohlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2] {ECO:0000313|Proteomes:UP000000591}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE016820; AAS54319.2; -; Genomic_DNA.
DR   RefSeq; NP_986495.2; NM_211557.2.
DR   STRING; 33169.AAS54319; -.
DR   EnsemblFungi; AAS54319; AAS54319; AGOS_AGL172W.
DR   GeneID; 4622788; -.
DR   KEGG; ago:AGOS_AGL172W; -.
DR   HOGENOM; HOG000168542; -.
DR   InParanoid; Q750W1; -.
DR   OMA; ITRIVLC; -.
DR   Proteomes; UP000000591; Chromosome VII.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0045121; C:membrane raft; IEA:EnsemblFungi.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0015385; F:sodium:proton antiporter activity; IBA:GO_Central.
DR   GO; GO:0030007; P:cellular potassium ion homeostasis; IBA:GO_Central.
DR   GO; GO:0097623; P:potassium ion export across plasma membrane; IEA:EnsemblFungi.
DR   GO; GO:0006970; P:response to osmotic stress; IEA:EnsemblFungi.
DR   GO; GO:0036376; P:sodium ion export across plasma membrane; IEA:EnsemblFungi.
DR   InterPro; IPR013928; Cation/H_antiporter_C.
DR   InterPro; IPR006153; Cation/H_exchanger.
DR   InterPro; IPR004712; Na+/H+_antiporter_fungi.
DR   PANTHER; PTHR31382:SF4; PTHR31382:SF4; 1.
DR   Pfam; PF00999; Na_H_Exchanger; 1.
DR   Pfam; PF08619; Nha1_C; 2.
PE   4: Predicted;
DR   PRODOM; Q750W1.
DR   SWISS-2DPAGE; Q750W1.
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000591};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        103..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        204..225
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        245..262
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        296..315
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        327..349
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        361..382
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        414..439
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          25..437
FT                   /note="Na_H_Exchanger"
FT                   /evidence="ECO:0000259|Pfam:PF00999"
FT   DOMAIN          465..802
FT                   /note="Nha1_C"
FT                   /evidence="ECO:0000259|Pfam:PF08619"
FT   DOMAIN          832..888
FT                   /note="Nha1_C"
FT                   /evidence="ECO:0000259|Pfam:PF08619"
FT   REGION          498..599
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          613..640
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          668..691
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          746..898
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        524..555
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        580..599
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        668..688
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        763..786
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        827..842
FT                   /note="Acidic"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        843..870
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        881..898
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   898 AA;  99376 MW;  FC5DDF4A68F3AE5A CRC64;
     MAVWDHLDVS KAHVAYACVG VFSCIFSLVS LFVKERLYIG ESTVAVIFGL IVGPQCLKWF
     DPTAWGNTDS ITLEISRVVL CLQIFAVAVE LPKKYMLKHW MSVTMLLIPV MTTGWLIIGL
     FVWLLIPGLN FSSSLLISAC ITATDPILAQ SVVSGKFAER VPGHLRNLLS AESGCNDGMA
     FPFIYLALNL VIYPGNGREI VKDWICVTIL YECVFGCLLG VVIGYAGRRA IRFAEDKKII
     DRESFLAFYV VLALMCAGFG SILGVDDLLV SFAAGAAFAW DGWFAKKTEE SKVSTVIDLL
     LNLAYFVYFG AIIPWKQFND PLIGTKVWRL ILLAIAVITL RRIPAVLFFK SMIPDIKSWR
     EALFVGHFGP IGVGAIFAAI LARAELEAHA TGEDTPLKEI PAQGTEHWQL IACVWPIVCF
     LIVTSIIVHG SSVAVITLGR HLNAITLTKS FTTHTTNGNN RSSSWMQRLP GLDKSGRSFS
     LHRIDTLARA ESLTRVSTVE TSGVPAKRAG GMQKKRGRKF GKNRAKDLFR TASRRADTTP
     FEDPALKEER LARERQAQAA AFALSREDRT DYEEKGTTEG YGESPSTQQS LGYSSNVTDL
     PQDTATLEEA DLSSDDLSHQ MDERVPFPSS SQGSSRLAEH YNEDHDPTVA YLEGNSVILE
     NKHGEIVGHS KRSKPAKDIE EGTQNDELSR RSSEVMNTLK KVISPAFLKK PIIDVDRGIK
     YHAYKVNDIL IIENEDGEVL RRYRINTHKE NGRPRTKPRP RTKTRSSSVV TKALSVVGLG
     RSKNSSPSSE DEAEPSDDLN QRPIQARRLT PVPSAYPPVV TGDVTGYTDI EDEDEDEDES
     YRSTDLSDQA HSDSDAPAFE DEETEVERAR RLTALGAFSA PRCDDDEEEV PRLTASKK
//

If you have problems or comments...

PBIL Back to PBIL home page