(data stored in ACNUC7421 zone)

SWISSPROT: Q750T1_ASHGO

ID   Q750T1_ASHGO            Unreviewed;      1497 AA.
AC   Q750T1;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 2.
DT   11-DEC-2019, entry version 124.
DE   SubName: Full=AGL142Cp {ECO:0000313|EMBL:AAS54349.2};
GN   ORFNames=AGOS_AGL142C {ECO:0000313|EMBL:AAS54349.2};
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811 {ECO:0000313|EMBL:AAS54349.2, ECO:0000313|Proteomes:UP000000591};
RN   [1] {ECO:0000313|EMBL:AAS54349.2, ECO:0000313|Proteomes:UP000000591}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Pohlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2] {ECO:0000313|Proteomes:UP000000591}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily.
CC       {ECO:0000256|SAAS:SAAS00709360}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00434}.
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DR   EMBL; AE016820; AAS54349.2; -; Genomic_DNA.
DR   RefSeq; NP_986525.2; NM_211587.2.
DR   STRING; 33169.AAS54349; -.
DR   EnsemblFungi; AAS54349; AAS54349; AGOS_AGL142C.
DR   GeneID; 4622818; -.
DR   KEGG; ago:AGOS_AGL142C; -.
DR   HOGENOM; HOG000162078; -.
DR   InParanoid; Q750T1; -.
DR   KO; K08711; -.
DR   OMA; ITHFFFI; -.
DR   Proteomes; UP000000591; Chromosome VII.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR   GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR   CDD; cd03233; ABCG_PDR_domain1; 1.
DR   CDD; cd03232; ABCG_PDR_domain2; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR013525; ABC_2_trans.
DR   InterPro; IPR029481; ABC_trans_N.
DR   InterPro; IPR003439; ABC_transporter-like.
DR   InterPro; IPR017871; ABC_transporter_CS.
DR   InterPro; IPR034001; ABCG_PDR_1.
DR   InterPro; IPR034003; ABCG_PDR_2.
DR   InterPro; IPR005285; Drug-R_PDR/CDR.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010929; PDR_CDR_ABC.
DR   Pfam; PF01061; ABC2_membrane; 2.
DR   Pfam; PF00005; ABC_tran; 2.
DR   Pfam; PF14510; ABC_trans_N; 1.
DR   Pfam; PF06422; PDR_CDR; 1.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   TIGRFAMs; TIGR00956; 3a01205; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE   3: Inferred from homology;
DR   PRODOM; Q750T1.
DR   SWISS-2DPAGE; Q750T1.
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00434,
KW   ECO:0000256|SAAS:SAAS00555301}; Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|SAAS:SAAS00709359, ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00434,
KW   ECO:0000256|SAAS:SAAS00555311};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000591};
KW   Repeat {ECO:0000256|SAAS:SAAS00709352};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00709342, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00709353,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS00709346}.
FT   TRANSMEM        507..529
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        541..562
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        618..636
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        648..668
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        755..775
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1178..1198
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1210..1229
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1263..1286
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1298..1322
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1328..1348
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1355..1373
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1450..1471
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          139..397
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000259|PROSITE:PS50893"
FT   DOMAIN          842..1084
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000259|PROSITE:PS50893"
FT   NP_BIND         878..885
FT                   /note="ATP"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00434"
FT   REGION          58..77
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          445..465
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1497 AA;  169902 MW;  BF1FB440D8ECCA05 CRC64;
     MEFFNANLTA NRASHVSAGA STSIGEADRP YVGLAEDLEE QEVIRSLAQT LSRSSAAEYE
     LQPTSADPSA LFGPDKDARL DPESDEFDPR YWVRTIRNLY ASDPDHYKPA ELCVVIQNLR
     VCGVSADTDY QATVGNSPLK ALRMLYQMTP FARGREKSEF DILKPLDVVF EPGRLCVVLG
     RPGAGCSTLL KTVGARTYGF TVAPESEISY SGFSQKEIKN HLRGEVIYSA ESDTHFASLP
     VGYTLEFAAR CRCPQVRPGG VKREVFYKHY AAAVMAMYGL SHTRYTKVGN DYIRGVSGGE
     RKRVSLAEVT LAGAKLQCWD NCTRGLDSAT ALEFVRALRD NAEVMRTTQL IAIYQCSEAA
     YSLFDDVLVL YEGYMIYFGP RKLAKGYFLR MGWECPPRQT SADFLTSVTS PFERKSQPGY
     EDKVPRTARE FYEYWLRSPE HAVAMKQIQR RIAEAKTDAA REQLRDHHIV RQARHVKSSS
     PYLISFYMQF RAIVDRNWQR LRGDPSVYLF SIVAYSIMGL ILASCFLNLK PDTNSLFNRG
     SALFTAVLLN SFFSFLEIMS LFEARAIVKK HKSYAFYRPS ADAFASIFTE LPAKFTVCIC
     FNVPFYFMVN LRRSTGAFFF YMLVSLTATF AMSHLFRSVG AACKTLYVTM FPASLLLLGL
     AVYVGFVIPQ KNILGWSRWL FYLNPIARIM EAMVANEFDG RIFECSRMVP DGSFYEGFPI
     SNKVCLSVGA VPGQSFVNGT RYIEFAYGYN TKNKWMNWGI VLAYAFFFLG VYLILIEYNK
     SGMQKGEMAV FLRSTLKKIK KQNKKAINCD IEFGNAPGKE SSTIGSDQSR ELIQRIGSDS
     IFHWRDVCYD IQIKNETRRI LTNVDGWVKP GTLTALMGYS GAGKTTLLDV LANRVRVGVV
     TGNIFVDGHL RDTSFQRKTG YCQQQDLHGR TQTVRDALKF SAYLRQPQSI SRAEKNAYVE
     DIIKLLGMEA YADAVVGVTG EGLNVEQRKR LTIGVELVAK PELLLFLDEP TSGLDSQTAW
     SICQLIKKLV NHGQAILCTI HQPSAILMQE FDRLLLLSNG GRTVYFGPLG EGCSTMIQYF
     ENHGSQKFPE ACNPAEFMLE IIGAAPGSHA LQDYHEIWKN SDEYQSVQEE LHRMEMELWH
     KPRFETSDQN KEFASSIWYQ YIIVSRRVLQ QYWRSPEYLW SKIFMSIFAS LFIGFSFFKS
     KTSIQGLQNQ MFAVFLFLVV LTPLVQQMLP QYVEQRDLFE VRERHSKTFS WKVFLLSQIT
     AEIPWAILGA TISFFCFYYP VGFYTHATDA ANRAERGFLF WLLCVTFYIF SATFGQFCIA
     GLEKAEPAAI LANFYFTMCL IFSGVLVTKD NLPRFWIWMY YLSPVTYLVS ALLSTGSGNM
     TVECAPEELI KFAPPKGLFC ALYLEPFANN AESVLLNPAA TDLCTVCPIK NSDYYLALVN
     IFYNHRWRDW GIFTIFVATN IIGFAATYWF FRVPKSTHIT IKTKANVKEQ EQEQEHQ
//

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