(data stored in ACNUC7421 zone)

SWISSPROT: Q750P2_ASHGO

ID   Q750P2_ASHGO            Unreviewed;       731 AA.
AC   Q750P2;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   11-DEC-2019, entry version 108.
DE   SubName: Full=AGL094Wp {ECO:0000313|EMBL:AAS54396.1};
GN   ORFNames=AGOS_AGL094W {ECO:0000313|EMBL:AAS54396.1};
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811 {ECO:0000313|EMBL:AAS54396.1, ECO:0000313|Proteomes:UP000000591};
RN   [1] {ECO:0000313|EMBL:AAS54396.1, ECO:0000313|Proteomes:UP000000591}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Pohlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2] {ECO:0000313|Proteomes:UP000000591}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
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DR   EMBL; AE016820; AAS54396.1; -; Genomic_DNA.
DR   RefSeq; NP_986572.1; NM_211634.1.
DR   STRING; 33169.AAS54396; -.
DR   EnsemblFungi; AAS54396; AAS54396; AGOS_AGL094W.
DR   GeneID; 4622871; -.
DR   KEGG; ago:AGOS_AGL094W; -.
DR   HOGENOM; HOG000216610; -.
DR   InParanoid; Q750P2; -.
DR   KO; K03240; -.
DR   OMA; NVAMIDY; -.
DR   Proteomes; UP000000591; Chromosome VII.
DR   GO; GO:0005851; C:eukaryotic translation initiation factor 2B complex; IBA:GO_Central.
DR   GO; GO:0032045; C:guanyl-nucleotide exchange factor complex; IEA:EnsemblFungi.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IBA:GO_Central.
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IEA:InterPro.
DR   GO; GO:0003743; F:translation initiation factor activity; IBA:GO_Central.
DR   GO; GO:0031369; F:translation initiation factor binding; IBA:GO_Central.
DR   GO; GO:0002183; P:cytoplasmic translational initiation; IEA:EnsemblFungi.
DR   GO; GO:0006446; P:regulation of translational initiation; IEA:EnsemblFungi.
DR   CDD; cd04197; eIF-2B_epsilon_N; 1.
DR   Gene3D; 1.25.40.180; -; 1.
DR   Gene3D; 3.90.550.10; -; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR035543; eIF-2B_epsilon_N.
DR   InterPro; IPR001451; Hexapep.
DR   InterPro; IPR016021; MIF4-like_sf.
DR   InterPro; IPR005835; NTP_transferase_dom.
DR   InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR   InterPro; IPR003307; W2_domain.
DR   Pfam; PF00132; Hexapep; 1.
DR   Pfam; PF00483; NTP_transferase; 1.
DR   Pfam; PF02020; W2; 1.
DR   SMART; SM00515; eIF5C; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   SUPFAM; SSF53448; SSF53448; 1.
DR   PROSITE; PS51363; W2; 1.
PE   4: Predicted;
DR   PRODOM; Q750P2.
DR   SWISS-2DPAGE; Q750P2.
KW   Reference proteome {ECO:0000313|Proteomes:UP000000591}.
FT   DOMAIN          553..724
FT                   /note="W2"
FT                   /evidence="ECO:0000259|PROSITE:PS51363"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          444..473
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          487..506
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        489..503
FT                   /note="Acidic"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   731 AA;  81518 MW;  8230FA206DE0F824 CRC64;
     MAGKKQRAKG QSGNANSAGK RNEVVQDERL QAVVLTDSFE TRFMPLTYEM PRCLMPLANV
     PLIEYTLEFL AKAGVHEVYL ICTSHAEQVQ EYIDNSKWNL PWSPFKVSTI LALEARSVGD
     AMRDLDNRGL ITGDFILVSG DLVTNMEFDR ALEAHRARRA EDKEHIVTMC LSTATQSHRT
     RSCEPAVFML DKSNDRCLYY QDIPLASSKR KTAVDIDPEL LEGVEEFKLR NDLIDCHIDI
     CSPLVPAIFQ ENFDYQYLRR DFVKGVLSSD LLKKHIYAYI TKEYAARVES WQTYDAISQD
     FLARWCYPLV LDSNLLEDQT YSYESKHVYK EKDVILAQSC KIGKCTAIGS GSTIGEGTFI
     ENSVIGRNCQ IGANVKIINS YIWENSIIGD NSVLNHSIVA AGAKLGSAVT LEDGCVIGFN
     VVVASSKTIP SGTRISAAPI TVSSMSVPTP SYSSDEDSDE DSGLHPATRS KSTAKAVQLV
     GESGVGYIYE SDDSDDSEET DDCDGAGANT LCTRMDELYL SDSSIYSASK TKKRRTLSTA
     SYYTDWEDGS DASEEEEDFE KEAIATVERA MEHNHDIDTA LLELNTLRMS LNVTYHEVRA
     ATVSAMLKRV YHFIATQTLG PKDAVAKVFA HWGPLFRRQA FTAAEYVDLM DVILHRVVSM
     RFDRPDFILF CVYSCLYDSD ILDEDVVYQW WAAAAADPAH ADVKTLTAKW VDWLQTADEE
     SGDDSGDDSD E
//

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