(data stored in ACNUC7421 zone)

SWISSPROT: Q750H4_ASHGO

ID   Q750H4_ASHGO            Unreviewed;      1222 AA.
AC   Q750H4;
DT   05-JUL-2004, integrated into UniProtKB/TrEMBL.
DT   05-JUL-2004, sequence version 1.
DT   11-DEC-2019, entry version 116.
DE   RecName: Full=Structural maintenance of chromosomes protein {ECO:0000256|PIRNR:PIRNR005719};
GN   ORFNames=AGOS_AGL023W {ECO:0000313|EMBL:AAS54467.1};
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811 {ECO:0000313|EMBL:AAS54467.1, ECO:0000313|Proteomes:UP000000591};
RN   [1] {ECO:0000313|EMBL:AAS54467.1, ECO:0000313|Proteomes:UP000000591}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Pohlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2] {ECO:0000313|Proteomes:UP000000591}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056
RC   {ECO:0000313|Proteomes:UP000000591};
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR005719}.
CC   -!- SIMILARITY: Belongs to the SMC family. {ECO:0000256|PIRNR:PIRNR005719}.
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DR   EMBL; AE016820; AAS54467.1; -; Genomic_DNA.
DR   RefSeq; NP_986643.1; NM_211705.1.
DR   STRING; 33169.AAS54467; -.
DR   EnsemblFungi; AAS54467; AAS54467; AGOS_AGL023W.
DR   GeneID; 4622942; -.
DR   KEGG; ago:AGOS_AGL023W; -.
DR   HOGENOM; HOG000195481; -.
DR   InParanoid; Q750H4; -.
DR   KO; K06636; -.
DR   OMA; YMEAIVV; -.
DR   Proteomes; UP000000591; Chromosome VII.
DR   GO; GO:0034990; C:nuclear mitotic cohesin complex; IEA:EnsemblFungi.
DR   GO; GO:0003680; F:AT DNA binding; IEA:EnsemblFungi.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0000217; F:DNA secondary structure binding; IEA:EnsemblFungi.
DR   GO; GO:0042802; F:identical protein binding; IEA:EnsemblFungi.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR   GO; GO:0006302; P:double-strand break repair; IEA:EnsemblFungi.
DR   GO; GO:0007064; P:mitotic sister chromatid cohesion; IEA:EnsemblFungi.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003395; RecF/RecN/SMC_N.
DR   InterPro; IPR024704; SMC.
DR   InterPro; IPR028468; Smc1.
DR   InterPro; IPR010935; SMC_hinge.
DR   InterPro; IPR036277; SMC_hinge_sf.
DR   PANTHER; PTHR18937:SF12; PTHR18937:SF12; 1.
DR   Pfam; PF06470; SMC_hinge; 1.
DR   Pfam; PF02463; SMC_N; 1.
DR   PIRSF; PIRSF005719; SMC; 1.
DR   SMART; SM00968; SMC_hinge; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   SUPFAM; SSF75553; SSF75553; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q750H4.
DR   SWISS-2DPAGE; Q750H4.
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleus {ECO:0000256|PIRNR:PIRNR005719};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000591}.
FT   DOMAIN          523..638
FT                   /note="SMC hinge"
FT                   /evidence="ECO:0000259|SMART:SM00968"
FT   COILED          173..200
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          251..274
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          317..365
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          396..423
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          488..521
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          706..740
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          807..925
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1037..1057
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1222 AA;  139038 MW;  C21007A6048F8A59 CRC64;
     MGRLIGLEVK NFKSYKGVHN VGFGGKNFIS IVGPNGSGKS NMMDAISFVL GIRSSHLRSS
     ALVDLIYRGR MEEGGSAHEN NPKSAYVTAF YVKQDASGAE RRMEFTRVIH NTGDSTYKLD
     GKTVGYKEYV DVLEGERILV KARNFLVFQG DVEQIASQSG VDLTKLFEQV SGSVQYQREY
     ERLKDDYEKA SAEYNESLKA RRKMQIDLKS FKEGVQKEEQ YISLLAERVK LQQQFMLWQL
     FHLQSKRSGL VASLKDSKAK LSQLKRQLSN EEAILGKSKS LVAKEELLLA RRRETLLQKQ
     QDKARLNAQL LPVGSARQGT TRRMVNIEKR IDSLQRDIER QESYVKQLKN QLKVVGKTKA
     SFEAELEKSA SGKFTLSEEQ KKEYEELKEV YLSSGGSEFE EKLAILQNKK EELSEEIAVF
     EKRIGISKTR AEHDLKVDIE RLEVEVSERT GNLNDKNAIH SEKVREWKQI QSEIESANNK
     EYELSYKLRE VLAKLDDLSA NQRETNKERK LRENVATLRR LFPGVRGLVH DLCRPKKEKY
     AVGVSTILGK NFDSVIVDSL SVAQQCISYL KKHRSGVASF IPLDTIDTSS PTLPAGDNTG
     CILTLDAIEY ESSLEKAMQY VCSDSIICDS LDIARNLKWN RNVKSKLVTL EGALIHRAGL
     MTGGITKNNT NRWDKEEYQS LLLLKDKIST ELSELTTGIR TGSIKSRDYE NEVSLLSTEI
     SSLRSQLNQL NRSMKEALTE LNYHDDLIEK EYSPKVDSLH KMVEEVDGQM ADIAKDKANL
     QASVYKDFSK KIGFDIGEYE QHTGGRLRKH SRELQQLQKE VMNIENKLEF ETERLESTIK
     RQQKAREDLK KVQGELDSLT SQETDIQSNL EQVTNQIAEE TKVLEEAQEK LKKKGNNIKI
     IEDTINDLHD SIQTCKREIT EWKEDIEKVG IERVNILKNC KMTNIELPLD SSALEDLAIE
     RIDAETIEAG NNISVDYSRL SARYKESSSH HIRDEFESSI KAIDNTLTEL QPNSKAVERF
     DEARDQFNAV SGESDKLKES ERKAKELYLK IKEKRINTFL ACFNHVRDNI DRIYRELTRN
     PGSTAELAGG SASLTLEDED EPYLGGIRYH ATPPMKRFKD MDYLSGGEKT MAALALLFAI
     NSYQPSPFFI LDEVDAALDV TNVERIAAYI RRHASPKMQF IVISLKSNLF SKSESMAGVF
     RNQHENSSMV ITTDLTQYAD DM
//

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