(data stored in ACNUC7421 zone)

SWISSPROT: SLT11_ASHGO

ID   SLT11_ASHGO             Reviewed;         331 AA.
AC   Q750K9;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   11-DEC-2019, entry version 76.
DE   RecName: Full=Pre-mRNA-splicing factor SLT11;
GN   Name=SLT11; OrderedLocusNames=AGR032W;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Involved in pre-mRNA splicing. Facilitates the cooperative
CC       formation of U2/U6 helix II in association with stem II in the
CC       spliceosome. Binds to RNA (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SLT11 family. {ECO:0000305}.
DR   EMBL; AE016820; AAS54521.1; -; Genomic_DNA.
DR   RefSeq; NP_986697.1; NM_211759.1.
DR   SMR; Q750K9; -.
DR   STRING; 33169.AAS54521; -.
DR   EnsemblFungi; AAS54521; AAS54521; AGOS_AGR032W.
DR   GeneID; 4622997; -.
DR   KEGG; ago:AGOS_AGR032W; -.
DR   HOGENOM; HOG000154338; -.
DR   InParanoid; Q750K9; -.
DR   KO; K12872; -.
DR   OMA; RNVCQCC; -.
DR   Proteomes; UP000000591; Chromosome VII.
DR   GO; GO:0000974; C:Prp19 complex; IBA:GO_Central.
DR   GO; GO:0071006; C:U2-type catalytic step 1 spliceosome; IBA:GO_Central.
DR   GO; GO:0071007; C:U2-type catalytic step 2 spliceosome; IBA:GO_Central.
DR   GO; GO:0036002; F:pre-mRNA binding; IBA:GO_Central.
DR   GO; GO:0017070; F:U6 snRNA binding; IBA:GO_Central.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:EnsemblFungi.
DR   CDD; cd12265; RRM_SLT11; 1.
DR   InterPro; IPR039171; Cwc2/Slt11.
DR   InterPro; IPR034356; Slt11_RRM.
DR   PANTHER; PTHR14089; PTHR14089; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q750K9.
DR   SWISS-2DPAGE; Q750K9.
KW   mRNA processing; mRNA splicing; Nucleus; Reference proteome; RNA-binding;
KW   Spliceosome.
FT   CHAIN           1..331
FT                   /note="Pre-mRNA-splicing factor SLT11"
FT                   /id="PRO_0000212421"
SQ   SEQUENCE   331 AA;  35718 MW;  9671C59BAD48B599 CRC64;
     MDEETPSICE QCLTDADLRM TRAARGAECK ICTLPFTLYH FKPPGAPRVT KTLVCRRCAA
     QRNVCQCCML DLAWKLPVAL RDELVSLVQG SDERTPEASN EMVRRFLALR GGQLGGARLT
     ADSAPLRELM GKMRAVAAAA APAARAHGGR EDAGEVPETQ LPFGGALATP ASRSFFIYGV
     DPALPEWELV DAVSQLVRTP DWRDAGSVSV VVRQDARCAG IRFRREELAQ AFVARLETLP
     AAAGAPKGVL RIRHLRMHVV AWPEFHLAAF GETKQQTEGI ARLATKTMRA DAEGASPARP
     AAPASAAGKV AKKAAAPRRQ GRRGPRPTLE L
//

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