(data stored in ACNUC10821 zone)

SWISSPROT: AGUA1_LISMF

ID   AGUA1_LISMF             Reviewed;         364 AA.
AC   Q725C6;
DT   16-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   08-MAY-2019, entry version 66.
DE   RecName: Full=Putative agmatine deiminase 1 {ECO:0000255|HAMAP-Rule:MF_01841};
DE            EC=3.5.3.12 {ECO:0000255|HAMAP-Rule:MF_01841};
DE   AltName: Full=Agmatine iminohydrolase 1 {ECO:0000255|HAMAP-Rule:MF_01841};
GN   Name=aguA1 {ECO:0000255|HAMAP-Rule:MF_01841};
GN   OrderedLocusNames=LMOf2365_0047;
OS   Listeria monocytogenes serotype 4b (strain F2365).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=265669;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F2365;
RX   PubMed=15115801; DOI=10.1093/nar/gkh562;
RA   Nelson K.E., Fouts D.E., Mongodin E.F., Ravel J., DeBoy R.T.,
RA   Kolonay J.F., Rasko D.A., Angiuoli S.V., Gill S.R., Paulsen I.T.,
RA   Peterson J.D., White O., Nelson W.C., Nierman W.C., Beanan M.J.,
RA   Brinkac L.M., Daugherty S.C., Dodson R.J., Durkin A.S., Madupu R.,
RA   Haft D.H., Selengut J., Van Aken S.E., Khouri H.M., Fedorova N.,
RA   Forberger H.A., Tran B., Kathariou S., Wonderling L.D., Uhlich G.A.,
RA   Bayles D.O., Luchansky J.B., Fraser C.M.;
RT   "Whole genome comparisons of serotype 4b and 1/2a strains of the food-
RT   borne pathogen Listeria monocytogenes reveal new insights into the
RT   core genome components of this species.";
RL   Nucleic Acids Res. 32:2386-2395(2004).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=agmatine + H2O = N-carbamoylputrescine + NH4(+);
CC         Xref=Rhea:RHEA:18037, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938,
CC         ChEBI:CHEBI:58145, ChEBI:CHEBI:58318; EC=3.5.3.12;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01841};
CC   -!- SIMILARITY: Belongs to the agmatine deiminase family.
CC       {ECO:0000255|HAMAP-Rule:MF_01841}.
DR   EMBL; AE017262; AAT02835.1; -; Genomic_DNA.
DR   RefSeq; WP_003724874.1; NC_002973.6.
DR   SMR; Q725C6; -.
DR   EnsemblBacteria; AAT02835; AAT02835; LMOf2365_0047.
DR   KEGG; lmf:LMOf2365_0047; -.
DR   HOGENOM; HOG000239346; -.
DR   KO; K10536; -.
DR   OMA; KQHGSLH; -.
DR   BioCyc; LMON265669:G1G0V-47-MONOMER; -.
DR   GO; GO:0047632; F:agmatine deiminase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0004668; F:protein-arginine deiminase activity; IEA:InterPro.
DR   GO; GO:0009446; P:putrescine biosynthetic process; IEA:InterPro.
DR   HAMAP; MF_01841; Agmatine_deimin; 1.
DR   InterPro; IPR017754; Agmatine_deiminase.
DR   InterPro; IPR007466; Peptidyl-Arg-deiminase_porph.
DR   PANTHER; PTHR31377; PTHR31377; 1.
DR   Pfam; PF04371; PAD_porph; 1.
DR   TIGRFAMs; TIGR03380; agmatine_aguA; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q725C6.
DR   SWISS-2DPAGE; Q725C6.
KW   Hydrolase.
FT   CHAIN         1    364       Putative agmatine deiminase 1.
FT                                /FTId=PRO_0000194331.
FT   ACT_SITE    356    356       Amidino-cysteine intermediate.
FT                                {ECO:0000255|HAMAP-Rule:MF_01841}.
SQ   SEQUENCE   364 AA;  41056 MW;  22DA502CC8620EB5 CRC64;
     MRTIDSSSKK DGFRMPGEFE KHAGCYIIWP ERPDNWRLGA KPAQKAFVDV ATAISRFEPV
     TVVASSSQYV NARYMLPDEI RVVEMDNDDA WVRDSGPTFV VNDSGDVRGV DWSFNSWGGL
     VDGLYFPWDK DDQVAQKICE LERKDRYRLA DFVLEGGSIH VDGEGTLVTT EECLLSEGRN
     PQLSKQQIEM VLKEYLNLEK IIWLKRGIYL DETNGHVDNI FNYVRPGVVA LAWTDDETDP
     QYEISKECFD ILSNETDAKG RKLEVHKINV PKPILITDEE SKGVDAVEGT LPREEGDRLA
     ASYINYYTAN GGVVFPLFGD PNDELAREKL RQLYPNCEVV GVKAREILLG GGNIHCITQQ
     VPRG
//

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