(data stored in ACNUC10821 zone)

SWISSPROT: RPOC_LISMF

ID   RPOC_LISMF              Reviewed;        1201 AA.
AC   Q724E9;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   08-MAY-2019, entry version 87.
DE   RecName: Full=DNA-directed RNA polymerase subunit beta' {ECO:0000255|HAMAP-Rule:MF_01322};
DE            Short=RNAP subunit beta' {ECO:0000255|HAMAP-Rule:MF_01322};
DE            EC=2.7.7.6 {ECO:0000255|HAMAP-Rule:MF_01322};
DE   AltName: Full=RNA polymerase subunit beta' {ECO:0000255|HAMAP-Rule:MF_01322};
DE   AltName: Full=Transcriptase subunit beta' {ECO:0000255|HAMAP-Rule:MF_01322};
GN   Name=rpoC {ECO:0000255|HAMAP-Rule:MF_01322};
GN   OrderedLocusNames=LMOf2365_0275;
OS   Listeria monocytogenes serotype 4b (strain F2365).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=265669;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F2365;
RX   PubMed=15115801; DOI=10.1093/nar/gkh562;
RA   Nelson K.E., Fouts D.E., Mongodin E.F., Ravel J., DeBoy R.T.,
RA   Kolonay J.F., Rasko D.A., Angiuoli S.V., Gill S.R., Paulsen I.T.,
RA   Peterson J.D., White O., Nelson W.C., Nierman W.C., Beanan M.J.,
RA   Brinkac L.M., Daugherty S.C., Dodson R.J., Durkin A.S., Madupu R.,
RA   Haft D.H., Selengut J., Van Aken S.E., Khouri H.M., Fedorova N.,
RA   Forberger H.A., Tran B., Kathariou S., Wonderling L.D., Uhlich G.A.,
RA   Bayles D.O., Luchansky J.B., Fraser C.M.;
RT   "Whole genome comparisons of serotype 4b and 1/2a strains of the food-
RT   borne pathogen Listeria monocytogenes reveal new insights into the
RT   core genome components of this species.";
RL   Nucleic Acids Res. 32:2386-2395(2004).
CC   -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription
CC       of DNA into RNA using the four ribonucleoside triphosphates as
CC       substrates. {ECO:0000255|HAMAP-Rule:MF_01322}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:11128, Rhea:RHEA-
CC         COMP:11129, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557,
CC         ChEBI:CHEBI:83400; EC=2.7.7.6; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_01322};
CC   -!- SUBUNIT: The RNAP catalytic core consists of 2 alpha, 1 beta, 1
CC       beta' and 1 omega subunit. When a sigma factor is associated with
CC       the core the holoenzyme is formed, which can initiate
CC       transcription. {ECO:0000255|HAMAP-Rule:MF_01322}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC       {ECO:0000255|HAMAP-Rule:MF_01322}.
DR   EMBL; AE017262; AAT03062.1; -; Genomic_DNA.
DR   RefSeq; WP_003728070.1; NC_002973.6.
DR   SMR; Q724E9; -.
DR   PRIDE; Q724E9; -.
DR   EnsemblBacteria; AAT03062; AAT03062; LMOf2365_0275.
DR   KEGG; lmf:LMOf2365_0275; -.
DR   HOGENOM; HOG000218387; -.
DR   KO; K03046; -.
DR   OMA; QGVEIND; -.
DR   BioCyc; LMON265669:G1G0V-290-MONOMER; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; ISS:JCVI.
DR   GO; GO:0006351; P:transcription, DNA-templated; ISS:JCVI.
DR   Gene3D; 1.10.132.30; -; 1.
DR   Gene3D; 1.10.274.100; -; 1.
DR   HAMAP; MF_01322; RNApol_bact_RpoC; 1.
DR   InterPro; IPR012754; DNA-dir_RpoC_beta_prime.
DR   InterPro; IPR000722; RNA_pol_asu.
DR   InterPro; IPR006592; RNA_pol_N.
DR   InterPro; IPR007080; RNA_pol_Rpb1_1.
DR   InterPro; IPR007066; RNA_pol_Rpb1_3.
DR   InterPro; IPR042102; RNA_pol_Rpb1_3_sf.
DR   InterPro; IPR007083; RNA_pol_Rpb1_4.
DR   InterPro; IPR007081; RNA_pol_Rpb1_5.
DR   InterPro; IPR038120; Rpb1_funnel_sf.
DR   Pfam; PF04997; RNA_pol_Rpb1_1; 1.
DR   Pfam; PF00623; RNA_pol_Rpb1_2; 1.
DR   Pfam; PF04983; RNA_pol_Rpb1_3; 1.
DR   Pfam; PF05000; RNA_pol_Rpb1_4; 1.
DR   Pfam; PF04998; RNA_pol_Rpb1_5; 2.
DR   SMART; SM00663; RPOLA_N; 1.
DR   TIGRFAMs; TIGR02386; rpoC_TIGR; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q724E9.
DR   SWISS-2DPAGE; Q724E9.
KW   DNA-directed RNA polymerase; Nucleotidyltransferase; Transcription;
KW   Transferase.
FT   CHAIN         1   1201       DNA-directed RNA polymerase subunit
FT                                beta'.
FT                                /FTId=PRO_0000067756.
SQ   SEQUENCE   1201 AA;  134755 MW;  A4CD5A0563E4BB0C CRC64;
     MLDVNNFEYM KIGLASPDKI RSWSHGEVKK PETINYRTLK PERDGLFCER IFGPMKDWEC
     SCGKYKRVRY KGVVCDRCGV EVTKSKVRRE RMGHIELAAP VSHIWYFKGI PSRMGLVMDM
     SPRALEEIIY FASYVVTEPG DTPLEKKQLL SEREYRVYRE KYGKGFSAGM GAEAIKKILA
     DIDLEKETND LKEELKSAQG QRRTRAIRRL EVMEAFRNSG NNPSWMVLDV LPVIPPEIRP
     MVQLEGGRFA TSDLNDLYRR VINRNNRLKR LLDLGAPNII VQNEKRMLQE AVDALIDNGR
     RGRPVTGPGN RPLKSLSHML KGKQGRFRQN LLGKRVDYSG RSVIVVGPNL KMYQCGLPKE
     MALELFKPFV MKELVGRGLA HNIKSAKRKI ERMAPEIWDV LEEVIREHPV LLNRAPTLHR
     LGIQAFEPTL VEGRAIRLHP LVCTAYNADF DGDQMAVHVP LSAEAQAEAR ILMLAAQNIL
     NPKDGKPVVT PSQDMVLGNY YLTLERENAV GEGTIFKDIN EAQLAYQNGY VHLHSRIAVF
     AGSIPNERFT DEQRNQLLIT TVGKLIFNTI LPKSFPYINE PTKFNLEIET PAKYFVDTTT
     DVRAHIAAQE LIDPFKKKIL GNIIAEVFKK FHITETSKML DRMKDLGFKI STKAGMTVGI
     ADILTLEEKH EILEKAHDTV EKITKSFRRG LITDDERYER VIGVWNAAKD EIQGKLILSL
     DRLNPIFMMQ DSGARGNISN FTQLAGMRGL MADPSGRIVE LPITSNFREG LTVLEYFIST
     HGARKGLTDT ALKTADSGYL TRRLVDVAQD VIIREDDCGT DRGLTIKAIR EGTEIIEPLE
     ERLEGRYSRK TIRHPETKEV IARENDLITE AIATQIVDAG IEEVTIRSAF TCNTKHGVCK
     KCYGKNLATG TEVEVGEAVG IIAAQSIGEP GTQLTMRTFH TGGVAGDDIT QGLPRIQEIF
     EARNPKGQAI ITEVGGEVVS IEEGRDRQQE ITIQGTDDRR SYNIPYTARL RVEEGTIVER
     GEALTEGSVD PKALIRVRDV LSVQEYLLAE VQKVYRMQGV EIGDKHVEVM VRQMLRKIRV
     MDTGDTNILP GTLMDIHTFT EANRDAILSG SQPATGRPVL LGITKASLET DSFLSAASFQ
     ETTRVLTDAA IKGKRDELLG LKENVILGKL VPAGTGIGRY RKLKSEVIKE TAEVTDEITN
     I
//

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