(data stored in ACNUC10821 zone)

SWISSPROT: INLI_LISMF

ID   INLI_LISMF              Reviewed;        1775 AA.
AC   Q723X5;
DT   17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   08-MAY-2019, entry version 97.
DE   RecName: Full=Internalin I;
DE   Flags: Precursor;
GN   Name=inlI; OrderedLocusNames=LMOf2365_0350;
OS   Listeria monocytogenes serotype 4b (strain F2365).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=265669;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F2365;
RX   PubMed=15115801; DOI=10.1093/nar/gkh562;
RA   Nelson K.E., Fouts D.E., Mongodin E.F., Ravel J., DeBoy R.T.,
RA   Kolonay J.F., Rasko D.A., Angiuoli S.V., Gill S.R., Paulsen I.T.,
RA   Peterson J.D., White O., Nelson W.C., Nierman W.C., Beanan M.J.,
RA   Brinkac L.M., Daugherty S.C., Dodson R.J., Durkin A.S., Madupu R.,
RA   Haft D.H., Selengut J., Van Aken S.E., Khouri H.M., Fedorova N.,
RA   Forberger H.A., Tran B., Kathariou S., Wonderling L.D., Uhlich G.A.,
RA   Bayles D.O., Luchansky J.B., Fraser C.M.;
RT   "Whole genome comparisons of serotype 4b and 1/2a strains of the food-
RT   borne pathogen Listeria monocytogenes reveal new insights into the
RT   core genome components of this species.";
RL   Nucleic Acids Res. 32:2386-2395(2004).
CC   -!- FUNCTION: A role in virulence could not be demonstrated.
CC       {ECO:0000250|UniProtKB:Q8YA32}.
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000255|PROSITE-
CC       ProRule:PRU00477}; Peptidoglycan-anchor {ECO:0000255|PROSITE-
CC       ProRule:PRU00477}.
CC   -!- SIMILARITY: Belongs to the internalin family. {ECO:0000305}.
DR   EMBL; AE017262; AAT03136.1; -; Genomic_DNA.
DR   RefSeq; WP_003724263.1; NC_002973.6.
DR   EnsemblBacteria; AAT03136; AAT03136; LMOf2365_0350.
DR   KEGG; lmf:LMOf2365_0350; -.
DR   HOGENOM; HOG000100912; -.
DR   OMA; EISAQGC; -.
DR   BioCyc; LMON265669:G1G0V-367-MONOMER; -.
DR   GO; GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 8.
DR   Gene3D; 3.80.10.10; -; 4.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR025875; Leu-rich_rpt_4.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR019931; LPXTG_anchor.
DR   InterPro; IPR012569; LRR-contain_adjacent_dom.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR009459; MucBP_dom.
DR   InterPro; IPR035986; PKD_dom_sf.
DR   Pfam; PF12799; LRR_4; 2.
DR   Pfam; PF13855; LRR_8; 1.
DR   Pfam; PF08191; LRR_adjacent; 1.
DR   Pfam; PF06458; MucBP; 3.
DR   SMART; SM00369; LRR_TYP; 11.
DR   SUPFAM; SSF49299; SSF49299; 1.
DR   SUPFAM; SSF81296; SSF81296; 1.
DR   PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
DR   PROSITE; PS51450; LRR; 23.
PE   3: Inferred from homology;
DR   PRODOM; Q723X5.
DR   SWISS-2DPAGE; Q723X5.
KW   Cell wall; Leucine-rich repeat; Peptidoglycan-anchor; Repeat;
KW   Secreted; Signal.
FT   SIGNAL        1     28       {ECO:0000255}.
FT   CHAIN        29   1743       Internalin I.
FT                                /FTId=PRO_0000252673.
FT   PROPEP     1744   1775       Removed by sortase. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00477}.
FT                                /FTId=PRO_0000252674.
FT   REPEAT      152    176       LRR 1.
FT   REPEAT      180    201       LRR 2.
FT   REPEAT      202    224       LRR 3.
FT   REPEAT      225    247       LRR 4.
FT   REPEAT      248    269       LRR 5.
FT   REPEAT      274    295       LRR 6.
FT   REPEAT      296    318       LRR 7.
FT   REPEAT      319    341       LRR 8.
FT   REPEAT      342    364       LRR 9.
FT   REPEAT      365    386       LRR 10.
FT   REPEAT      387    409       LRR 11.
FT   REPEAT      410    431       LRR 12.
FT   REPEAT      432    453       LRR 13.
FT   REPEAT      454    475       LRR 14.
FT   REPEAT      476    497       LRR 15.
FT   REPEAT      498    519       LRR 16.
FT   REPEAT      520    541       LRR 17.
FT   REPEAT      542    563       LRR 18.
FT   REPEAT      564    585       LRR 19.
FT   REPEAT      586    607       LRR 20.
FT   REPEAT      608    629       LRR 21.
FT   REPEAT      630    650       LRR 22.
FT   REPEAT      654    675       LRR 23.
FT   REPEAT      682    704       LRR 24.
FT   REPEAT      705    726       LRR 25.
FT   REPEAT      727    748       LRR 26.
FT   REPEAT      749    770       LRR 27.
FT   DOMAIN      782    869       LRRCT.
FT   DOMAIN     1507   1566       MucBP 1.
FT   DOMAIN     1572   1631       MucBP 2.
FT   DOMAIN     1641   1702       MucBP 3.
FT   MOTIF      1740   1744       LPXTG sorting signal.
FT                                {ECO:0000255|PROSITE-ProRule:PRU00477}.
FT   MOD_RES    1743   1743       Pentaglycyl murein peptidoglycan amidated
FT                                threonine. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00477}.
SQ   SEQUENCE   1775 AA;  191295 MW;  2D8052CF7A4C4443 CRC64;
     MKKKFSIVII SVLLLGYLAP FDTLLVGADE TTVTEDTTVK TAETETATEA TESESGSDNE
     KAEEPKEAEA SKETTEKEEK AKTKEPASNI KTEINTDKSQ LKQTNLKAVV PAGSTYNSLF
     PDDNLAKKLA VIITGNAAAT GNESVDSAAL LAISQLDLSG ETGNDPTDIS NIEGLQYLEN
     LTSLNLSENN ISDLAPIKDL VNLVSLNLSS NRTLVNLSGV EGLVNLQELN VSANKALEDI
     SQVAALPVLK EISAQGCNIK TLELDNPAGA ILPELETFYL QENDLTDLTS LAKLPKLKNL
     YIKGNASLKS LATLKGATKL QLIDASNCTD LETLGDISGL SELEMIQLSG CSKLKEITSL
     KDLPNLVNIT ADSCAIEDLG TLNNLPKLQT LILSDNKDLT NINAITDMPQ LKTLALDGCG
     ITSIGTLDNL PKLEKLDLKE NQLTSISEIN DLPRLSYLDV SVNYLTTIGE LKKLPLLEWL
     NVSSNRLSDV STLTNFPSLN YINVSNNVIR TVGKMTELPS LKEFYAQNNN VSDISMIHDM
     PNLRKVDASN NLITNIGTFD NLPKLQNLDV HSNRITNTSV IHDLPSLETF YAQNNLITNI
     GTMDNLPELT YVDLSFNRIP SLAPIGDLPK LEILKVTDNY SYLRSLGTMD GVSKLRNLEL
     QNNYLNYTGT EGNLSALSDL TNLTELNLRD NGYISDISGL STLSRLIYLN LDSNKIKDIS
     ALSNLTTLQE LTLENNQIED ISALSDLDNL NKLALSKNKI IDISPAANMV NRGASVTASN
     QTYTLPTVLS YQSSFTIDNP VVWYDGTPLA PSSIAHSGTY KDGEITWTNM TAASSSTEFN
     FNRLKDGLTF SGTITQPYKS AVKVTANAEQ TYTIGDTISE EQFLKDVNAK SSDGAPVTSD
     FATVVDLNTF GEYEVTLTSE KDGIQGDSCK VIVKVLHGAP VISADQTINY DKHATITEKQ
     FLEDVHASTD LNTAITTNFS TAVNLNKGGD YTVALNSENE DGVKAETVYV TVTVDKDPAP
     IISAKTDITY DKFSKKTEAA FLDDIDADTN DGSIITSNFA TAVNLDKAGD YTVTLNSINS
     DGVASTPTAI IVHVEKEKIA TISANTAQQY EKYAEINETQ FLKDVHASIN ASPTTAVLES
     DFETVVKLDV PGTYTVTITA TNEDGGVSAP KEVSVIVKKL PAPEITADKE ITYPKFDEVS
     EAEFLSDIHA TINEKNVTIT SNFSADVNLN KAGDYTVTLN ATNEDGVKAT PVEVIVHVQQ
     GERPVITADA TISYDKFANI TEAKFLEDIH ATSSDGQSST VITSNFETAT NFKTAMSYTV
     TLNAVNEDGI SAEPVAVTVT INKEPAATLK ADAEVSYAKN EAVTESDFFK DVHLEGAEAP
     STAKATSNFD SVVDRSKTGD YTVTINATNE DGAVSTPIEV IVHIGAESAP VITANAEVKY
     NKHEQTDERR FLYDSDAKID EANVEIKTDF AEKVDINKVG TYTVTLTATN EDGQAANPVE
     VSVIVSDAAA EKVNVKYVDE NGAEISAAET LTGNLDDAFS IDAKSIAGYK CDATLSGVFS
     TVEQTVVFHY KAIEPGVVTI KYEDANGKAV AEDKQITGEV GDDFEAEAQT VSGYSCRAIA
     SGKITEEPQT ITFTYTTATP SKKSGEITVQ YVDESGKKLA DSKKVTGDID DSYSVEAKAI
     DGYSVVGDDS AKGVFTEKSQ TVTFKYKKNT QVSKDEPKVK GKTNQPPSAD TKLKVDNNTL
     PATGDTENMA LAVLIGFNML LVASIFLFRK PKTNQ
//

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