(data stored in ACNUC10821 zone)

SWISSPROT: TAL2_LISMF

ID   TAL2_LISMF              Reviewed;         218 AA.
AC   Q723W2;
DT   07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   08-MAY-2019, entry version 89.
DE   RecName: Full=Probable transaldolase 2 {ECO:0000255|HAMAP-Rule:MF_00494};
DE            EC=2.2.1.2 {ECO:0000255|HAMAP-Rule:MF_00494};
GN   Name=tal2 {ECO:0000255|HAMAP-Rule:MF_00494};
GN   OrderedLocusNames=LMOf2365_0363;
OS   Listeria monocytogenes serotype 4b (strain F2365).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=265669;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F2365;
RX   PubMed=15115801; DOI=10.1093/nar/gkh562;
RA   Nelson K.E., Fouts D.E., Mongodin E.F., Ravel J., DeBoy R.T.,
RA   Kolonay J.F., Rasko D.A., Angiuoli S.V., Gill S.R., Paulsen I.T.,
RA   Peterson J.D., White O., Nelson W.C., Nierman W.C., Beanan M.J.,
RA   Brinkac L.M., Daugherty S.C., Dodson R.J., Durkin A.S., Madupu R.,
RA   Haft D.H., Selengut J., Van Aken S.E., Khouri H.M., Fedorova N.,
RA   Forberger H.A., Tran B., Kathariou S., Wonderling L.D., Uhlich G.A.,
RA   Bayles D.O., Luchansky J.B., Fraser C.M.;
RT   "Whole genome comparisons of serotype 4b and 1/2a strains of the food-
RT   borne pathogen Listeria monocytogenes reveal new insights into the
RT   core genome components of this species.";
RL   Nucleic Acids Res. 32:2386-2395(2004).
CC   -!- FUNCTION: Transaldolase is important for the balance of
CC       metabolites in the pentose-phosphate pathway. {ECO:0000255|HAMAP-
CC       Rule:MF_00494}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-
CC         phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-
CC         phosphate; Xref=Rhea:RHEA:17053, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:57483, ChEBI:CHEBI:57634, ChEBI:CHEBI:59776;
CC         EC=2.2.1.2; Evidence={ECO:0000255|HAMAP-Rule:MF_00494};
CC   -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-
CC       glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-
CC       ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative
CC       stage): step 2/3. {ECO:0000255|HAMAP-Rule:MF_00494}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00494}.
CC   -!- SIMILARITY: Belongs to the transaldolase family. Type 3B
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_00494}.
DR   EMBL; AE017262; AAT03149.1; -; Genomic_DNA.
DR   RefSeq; WP_003723193.1; NC_002973.6.
DR   SMR; Q723W2; -.
DR   EnsemblBacteria; AAT03149; AAT03149; LMOf2365_0363.
DR   KEGG; lmf:LMOf2365_0363; -.
DR   HOGENOM; HOG000226073; -.
DR   KO; K00616; -.
DR   OMA; APNVVIK; -.
DR   BioCyc; LMON265669:G1G0V-380-MONOMER; -.
DR   UniPathway; UPA00115; UER00414.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016832; F:aldehyde-lyase activity; IEA:InterPro.
DR   GO; GO:0004801; F:sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-UniRule.
DR   CDD; cd00956; Transaldolase_FSA; 1.
DR   Gene3D; 3.20.20.70; -; 1.
DR   HAMAP; MF_00494; Transaldolase_3b; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR001585; TAL/FSA.
DR   InterPro; IPR022999; Transaldolase_3B.
DR   InterPro; IPR004731; Transaldolase_3B/F6P_aldolase.
DR   InterPro; IPR018225; Transaldolase_AS.
DR   InterPro; IPR033919; TSA/FSA_arc/bac.
DR   PANTHER; PTHR10683; PTHR10683; 1.
DR   Pfam; PF00923; TAL_FSA; 1.
DR   TIGRFAMs; TIGR00875; fsa_talC_mipB; 1.
DR   PROSITE; PS01054; TRANSALDOLASE_1; 1.
DR   PROSITE; PS00958; TRANSALDOLASE_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q723W2.
DR   SWISS-2DPAGE; Q723W2.
KW   Cytoplasm; Pentose shunt; Schiff base; Transferase.
FT   CHAIN         1    218       Probable transaldolase 2.
FT                                /FTId=PRO_0000173674.
FT   ACT_SITE     83     83       Schiff-base intermediate with substrate.
FT                                {ECO:0000255|HAMAP-Rule:MF_00494}.
SQ   SEQUENCE   218 AA;  23551 MW;  CFC83FA79509A312 CRC64;
     MKFFLDTASV SEIKRISELG LVDGVTTNPT IIAKEGRPFE EVIKEICSIV DGPVSAEVIG
     LEADKMVEEA RILAKWAPNV VVKIPMTEEG LKAVHTLTAE GIKTNVTLIF TVSQGLMAAK
     AGATYISPFL GRLDDIGTDG MILIKNLKKV LDNYGLKAEI ISASIRHIGH LEEAAEAGAH
     IATIPGSLFP KLWSHPLTDK GIEGFLKDWE AFSQKEGN
//

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