(data stored in ACNUC10821 zone)

SWISSPROT: MOGR_LISMF

ID   MOGR_LISMF              Reviewed;         306 AA.
AC   Q722M0;
DT   25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   05-DEC-2018, entry version 64.
DE   RecName: Full=Motility gene repressor MogR;
GN   Name=mogR; OrderedLocusNames=LMOf2365_0710;
OS   Listeria monocytogenes serotype 4b (strain F2365).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Listeriaceae; Listeria.
OX   NCBI_TaxID=265669;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=F2365;
RX   PubMed=15115801; DOI=10.1093/nar/gkh562;
RA   Nelson K.E., Fouts D.E., Mongodin E.F., Ravel J., DeBoy R.T.,
RA   Kolonay J.F., Rasko D.A., Angiuoli S.V., Gill S.R., Paulsen I.T.,
RA   Peterson J.D., White O., Nelson W.C., Nierman W.C., Beanan M.J.,
RA   Brinkac L.M., Daugherty S.C., Dodson R.J., Durkin A.S., Madupu R.,
RA   Haft D.H., Selengut J., Van Aken S.E., Khouri H.M., Fedorova N.,
RA   Forberger H.A., Tran B., Kathariou S., Wonderling L.D., Uhlich G.A.,
RA   Bayles D.O., Luchansky J.B., Fraser C.M.;
RT   "Whole genome comparisons of serotype 4b and 1/2a strains of the food-
RT   borne pathogen Listeria monocytogenes reveal new insights into the
RT   core genome components of this species.";
RL   Nucleic Acids Res. 32:2386-2395(2004).
CC   -!- FUNCTION: Transcriptional repressor of flagellar motility genes,
CC       such as flaA, during extracellular growth at 37 degrees Celsius
CC       and during intracellular infection. Binds directly to gene
CC       promoter region and probably prevents RNA polymerase binding. At
CC       low temperatures, MogR repression activity is modulated by the
CC       DegU response regulator in an unknown mechanism. Required for full
CC       virulence (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
DR   EMBL; AE017262; AAT03491.1; -; Genomic_DNA.
DR   RefSeq; WP_003724414.1; NC_002973.6.
DR   SMR; Q722M0; -.
DR   EnsemblBacteria; AAT03491; AAT03491; LMOf2365_0710.
DR   KEGG; lmf:LMOf2365_0710; -.
DR   HOGENOM; HOG000253222; -.
DR   OMA; VYQFCQR; -.
DR   BioCyc; LMON265669:G1G0V-727-MONOMER; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.120.1030; -; 1.
DR   InterPro; IPR021009; MogR_DNA-bd.
DR   InterPro; IPR038245; MogR_N_sf.
DR   Pfam; PF12181; MogR_DNAbind; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q722M0.
DR   SWISS-2DPAGE; Q722M0.
KW   Cytoplasm; DNA-binding; Repressor; Transcription;
KW   Transcription regulation; Virulence.
FT   CHAIN         1    306       Motility gene repressor MogR.
FT                                /FTId=PRO_0000247905.
SQ   SEQUENCE   306 AA;  35284 MW;  0E7576A3A3BF51A6 CRC64;
     MPKSEIRKLL QEIKKQVDNP GNSSTTEIKK MASEAGIDEK TAEEIYHLLT EFYQAVEEHG
     GIEKYMHSNI SWLKIELELL SACYQIAILE DMKVLDISEM LSLNDLRIFP KTPSQLQNTY
     YKLKKELIQV EDIPKNKPGR KRKTQKNTKK EKTNIFGKVV PAEFKAPTSI KEQISYDKSR
     EKNLVDLLSG VKSNVQLLSE NQGEENNVYD LLKSIYSLSS LAVQKEELDK KYQDLQTKCQ
     ELEQENSYLK QQNETMTDSF HTLVLQVADF AYASDLDQIQ ALPLFSQQLV VTLNQLGVFK
     ENYKQM
//

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