(data stored in SCRATCH3701 zone)

SWISSPROT: NTRXL_RICTY

ID   NTRXL_RICTY             Reviewed;         475 AA.
AC   Q68WH4;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   11-DEC-2019, entry version 96.
DE   RecName: Full=Putative response regulator NtrX-like;
GN   OrderedLocusNames=RT0550;
OS   Rickettsia typhi (strain ATCC VR-144 / Wilmington).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX   NCBI_TaxID=257363;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-144 / Wilmington;
RX   PubMed=15317790; DOI=10.1128/jb.186.17.5842-5855.2004;
RA   McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E.,
RA   McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E.,
RA   Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A., Hong C.,
RA   Yu X.-J., Walker D.H., Weinstock G.M.;
RT   "Complete genome sequence of Rickettsia typhi and comparison with sequences
RT   of other Rickettsiae.";
RL   J. Bacteriol. 186:5842-5855(2004).
CC   -!- FUNCTION: Member of the two-component regulatory system RT0550/RT0603.
CC       {ECO:0000250}.
DR   EMBL; AE017197; AAU04018.1; -; Genomic_DNA.
DR   RefSeq; WP_011190999.1; NC_006142.1.
DR   SMR; Q68WH4; -.
DR   STRING; 257363.RT0550; -.
DR   EnsemblBacteria; AAU04018; AAU04018; RT0550.
DR   KEGG; rty:RT0550; -.
DR   eggNOG; ENOG4105C1W; Bacteria.
DR   eggNOG; COG2204; LUCA.
DR   HOGENOM; HOG000058489; -.
DR   KO; K13599; -.
DR   OMA; PTNSRVM; -.
DR   OrthoDB; 123059at2; -.
DR   BioCyc; RTYP257363:G1G0L-556-MONOMER; -.
DR   Proteomes; UP000000604; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00156; REC; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR002197; HTH_Fis.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   InterPro; IPR002078; Sigma_54_int.
DR   InterPro; IPR025944; Sigma_54_int_dom_CS.
DR   Pfam; PF02954; HTH_8; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   Pfam; PF00158; Sigma54_activat; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
DR   PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR   PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q68WH4.
DR   SWISS-2DPAGE; Q68WH4.
KW   ATP-binding; Nucleotide-binding; Phosphoprotein; Transcription;
KW   Transcription regulation; Two-component regulatory system.
FT   CHAIN           1..475
FT                   /note="Putative response regulator NtrX-like"
FT                   /id="PRO_0000282385"
FT   DOMAIN          5..121
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DOMAIN          143..369
FT                   /note="Sigma-54 factor interaction"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
FT   NP_BIND         171..178
FT                   /note="ATP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
FT   NP_BIND         232..241
FT                   /note="ATP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
FT   MOD_RES         54
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   475 AA;  53894 MW;  DE4BD0677D9C9E61 CRC64;
     MSQLDVLILD DEESIRNLIA ANLKDEGFNP KVAANSTQAL KIISEKPVSA VILDIWLQGS
     EIDGLGVLEI IKKRYPLIPV IIISGHGTIE TAVNAIKMGA YDYIEKPFNN DKLIILLKRA
     CEVTKLKREN IDLKSKVIDK TELVGGCSVT LKYKMEIEKA ASSSSRIMIH GKVGSGKELA
     ARLIHKQSKR VNNPFIIFSP TCMTTEKINQ ELFGESEKQE NNNKRPTILE FANNGTLYID
     EVSNIPIPIQ VKLLKFLKDQ TITKPCGKKT KVDIKIITST SKNIQDEVNN GKFLEDLYYR
     LNVFSLKVPS LYERKEDIPL LVKYFVKQLS KFSGLKERHF SDEAITALQS YEWPGNIRQL
     RNVVEWTLIM NPLTTGNNEI IKPYMIPSEI LANSANLTKL EDSFDMLSMP LREAREVFER
     QYLSAQMSRF NNNISKTSSF VGMERSALHR KLKLLSLHIP PTNKINEEEY EKANA
//

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