(data stored in ACNUC7421 zone)

SWISSPROT: Q5LXF4_RUEPO

ID   Q5LXF4_RUEPO            Unreviewed;       212 AA.
AC   Q5LXF4;
DT   01-FEB-2005, integrated into UniProtKB/TrEMBL.
DT   01-FEB-2005, sequence version 1.
DT   08-MAY-2019, entry version 70.
DE   RecName: Full=Acyl-homoserine-lactone synthase {ECO:0000256|RuleBase:RU361135};
DE            EC=2.3.1.184 {ECO:0000256|RuleBase:RU361135};
DE   AltName: Full=Autoinducer synthesis protein {ECO:0000256|RuleBase:RU361135};
GN   OrderedLocusNames=SPO0372 {ECO:0000313|EMBL:AAV93690.1};
OS   Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)
OS   (Silicibacter pomeroyi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Ruegeria.
OX   NCBI_TaxID=246200 {ECO:0000313|EMBL:AAV93690.1, ECO:0000313|Proteomes:UP000001023};
RN   [1] {ECO:0000313|EMBL:AAV93690.1, ECO:0000313|Proteomes:UP000001023}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700808 / DSM 15171 / DSS-3
RC   {ECO:0000313|Proteomes:UP000001023};
RX   PubMed=15602564; DOI=10.1038/nature03170;
RA   Moran M.A., Buchan A., Gonzalez J.M., Heidelberg J.F., Whitman W.B.,
RA   Kiene R.P., Henriksen J.R., King G.M., Belas R., Fuqua C., Brinkac L.,
RA   Lewis M., Johri S., Weaver B., Pai G., Eisen J.A., Rahe E.,
RA   Sheldon W.M., Ye W., Miller T.R., Carlton J., Rasko D.A.,
RA   Paulsen I.T., Ren Q., Daugherty S.C., Deboy R.T., Dodson R.J.,
RA   Durkin A.S., Madupu R., Nelson W.C., Sullivan S.A., Rosovitz M.J.,
RA   Haft D.H., Selengut J., Ward N.;
RT   "Genome sequence of Silicibacter pomeroyi reveals adaptations to the
RT   marine environment.";
RL   Nature 432:910-913(2004).
RN   [2] {ECO:0000313|EMBL:AAV93690.1, ECO:0000313|Proteomes:UP000001023}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 700808 / DSM 15171 / DSS-3
RC   {ECO:0000313|Proteomes:UP000001023};
RX   PubMed=25780504; DOI=10.1186/1944-3277-9-11;
RA   Rivers A.R., Smith C.B., Moran M.A.;
RT   "An updated genome annotation for the model marine bacterium Ruegeria
RT   pomeroyi DSS-3.";
RL   Stand. Genomic Sci. 9:11-11(2014).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a fatty acyl-[ACP] + S-adenosyl-L-methionine = an N-acyl-
CC         L-homoserine lactone + H(+) + holo-[ACP] + S-methyl-5'-
CC         thioadenosine; Xref=Rhea:RHEA:10096, Rhea:RHEA-COMP:9685,
CC         Rhea:RHEA-COMP:14125, ChEBI:CHEBI:15378, ChEBI:CHEBI:17509,
CC         ChEBI:CHEBI:55474, ChEBI:CHEBI:59789, ChEBI:CHEBI:64479,
CC         ChEBI:CHEBI:138651; EC=2.3.1.184;
CC         Evidence={ECO:0000256|RuleBase:RU361135};
CC   -!- SIMILARITY: Belongs to the autoinducer synthase family.
CC       {ECO:0000256|PROSITE-ProRule:PRU00533,
CC       ECO:0000256|RuleBase:RU361135}.
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DR   EMBL; CP000031; AAV93690.1; -; Genomic_DNA.
DR   RefSeq; WP_011046133.1; NC_003911.12.
DR   STRING; 246200.SPO0372; -.
DR   EnsemblBacteria; AAV93690; AAV93690; SPO0372.
DR   KEGG; sil:SPO0372; -.
DR   eggNOG; ENOG4105NNS; Bacteria.
DR   eggNOG; COG3916; LUCA.
DR   HOGENOM; HOG000207772; -.
DR   KO; K20249; -.
DR   OMA; ECTRFCL; -.
DR   OrthoDB; 1725271at2; -.
DR   BioCyc; RPOM246200:G1G48-379-MONOMER; -.
DR   Proteomes; UP000001023; Chromosome.
DR   GO; GO:0061579; F:N-acyl homoserine lactone synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009372; P:quorum sensing; IEA:UniProtKB-UniRule.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR001690; Autoind_synthase.
DR   PANTHER; PTHR39322; PTHR39322; 1.
DR   Pfam; PF00765; Autoind_synth; 1.
DR   PRINTS; PR01549; AUTOINDCRSYN.
DR   SUPFAM; SSF55729; SSF55729; 1.
DR   PROSITE; PS51187; AUTOINDUCER_SYNTH_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q5LXF4.
DR   SWISS-2DPAGE; Q5LXF4.
KW   Autoinducer synthesis {ECO:0000256|PROSITE-ProRule:PRU00533,
KW   ECO:0000256|RuleBase:RU361135};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001023};
KW   Quorum sensing {ECO:0000256|PROSITE-ProRule:PRU00533,
KW   ECO:0000256|RuleBase:RU361135};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001023};
KW   S-adenosyl-L-methionine {ECO:0000256|RuleBase:RU361135};
KW   Transferase {ECO:0000256|RuleBase:RU361135}.
SQ   SEQUENCE   212 AA;  23935 MW;  9349AEA2A513A2FB CRC64;
     MLRYLYADEL HQYPKLARSM FLDRADQFKT RLGWDVHVNE DGEERDQYDA LNPLYVIWEE
     PDGSHGGSMR FLPTTGPVMI NDVFGHLTGG SPICSPLIWE VTRFCMSRRA SSRVAGAIML
     SGGEVMEGFG LTHIAGVFDE RMIRIYRLIG SSPEVLGSEG EGRDRISVGL WPFSPADCAR
     VSERAGISRE LSRLWFNRAF GKVNRRRFAQ TG
//

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