(data stored in ACNUC7421 zone)

SWISSPROT: Q5LWC5_RUEPO

ID   Q5LWC5_RUEPO            Unreviewed;       648 AA.
AC   Q5LWC5;
DT   01-FEB-2005, integrated into UniProtKB/TrEMBL.
DT   01-FEB-2005, sequence version 1.
DT   08-MAY-2019, entry version 77.
DE   SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:AAV93735.1};
GN   Name=pbpA {ECO:0000313|EMBL:AAV93735.1};
GN   OrderedLocusNames=SPO0417 {ECO:0000313|EMBL:AAV93735.1};
OS   Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)
OS   (Silicibacter pomeroyi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Ruegeria.
OX   NCBI_TaxID=246200 {ECO:0000313|EMBL:AAV93735.1, ECO:0000313|Proteomes:UP000001023};
RN   [1] {ECO:0000313|EMBL:AAV93735.1, ECO:0000313|Proteomes:UP000001023}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700808 / DSM 15171 / DSS-3
RC   {ECO:0000313|Proteomes:UP000001023};
RX   PubMed=15602564; DOI=10.1038/nature03170;
RA   Moran M.A., Buchan A., Gonzalez J.M., Heidelberg J.F., Whitman W.B.,
RA   Kiene R.P., Henriksen J.R., King G.M., Belas R., Fuqua C., Brinkac L.,
RA   Lewis M., Johri S., Weaver B., Pai G., Eisen J.A., Rahe E.,
RA   Sheldon W.M., Ye W., Miller T.R., Carlton J., Rasko D.A.,
RA   Paulsen I.T., Ren Q., Daugherty S.C., Deboy R.T., Dodson R.J.,
RA   Durkin A.S., Madupu R., Nelson W.C., Sullivan S.A., Rosovitz M.J.,
RA   Haft D.H., Selengut J., Ward N.;
RT   "Genome sequence of Silicibacter pomeroyi reveals adaptations to the
RT   marine environment.";
RL   Nature 432:910-913(2004).
RN   [2] {ECO:0000313|EMBL:AAV93735.1, ECO:0000313|Proteomes:UP000001023}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 700808 / DSM 15171 / DSS-3
RC   {ECO:0000313|Proteomes:UP000001023};
RX   PubMed=25780504; DOI=10.1186/1944-3277-9-11;
RA   Rivers A.R., Smith C.B., Moran M.A.;
RT   "An updated genome annotation for the model marine bacterium Ruegeria
RT   pomeroyi DSS-3.";
RL   Stand. Genomic Sci. 9:11-11(2014).
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000031; AAV93735.1; -; Genomic_DNA.
DR   RefSeq; WP_011046178.1; NC_003911.12.
DR   STRING; 246200.SPO0417; -.
DR   EnsemblBacteria; AAV93735; AAV93735; SPO0417.
DR   KEGG; sil:SPO0417; -.
DR   eggNOG; ENOG4105CJN; Bacteria.
DR   eggNOG; COG0768; LUCA.
DR   HOGENOM; HOG000266119; -.
DR   KO; K05515; -.
DR   OMA; SCDTYYY; -.
DR   OrthoDB; 423699at2; -.
DR   BioCyc; RPOM246200:G1G48-424-MONOMER; -.
DR   Proteomes; UP000001023; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR   GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR005311; PBP_dimer.
DR   InterPro; IPR036138; PBP_dimer_sf.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   InterPro; IPR017790; Penicillin-binding_protein_2.
DR   Pfam; PF03717; PBP_dimer; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56519; SSF56519; 1.
DR   SUPFAM; SSF56601; SSF56601; 1.
DR   TIGRFAMs; TIGR03423; pbp2_mrdA; 1.
PE   4: Predicted;
DR   PRODOM; Q5LWC5.
DR   SWISS-2DPAGE; Q5LWC5.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001023};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001023};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     20     39       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       62    236       PBP_dimer. {ECO:0000259|Pfam:PF03717}.
FT   DOMAIN      269    603       Transpeptidase. {ECO:0000259|Pfam:
FT                                PF00905}.
SQ   SEQUENCE   648 AA;  71412 MW;  40438B07C7529E61 CRC64;
     MRRSARDMDK VQRVLTRRTL LLGGIQAAFI GGLAMRMRYM QVDQADQFRL LAEENRINIR
     LIPPSRGELF DRNGAIIAQN TPSYRIVMVR EDAGDVDAVV ANLQRLIPLD PEELDRALAE
     MRRSPPFLPV TLADQISWEH ISKVAVNAPA LPGITPEVGL TRVYPQASDF AHVVGYVGPV
     SDYDLSQIQD PEPVLRIPRF QIGKVGLEAK QEDLLRGKAG AKRVEVNANG RVMRELDRRE
     GKPGADLQLT VDSALQSYVQ ARLGQESAAA VVIDCETGDL RAIASAPSFD PNLFVRGISV
     ADYRGLTEDP YRPLANKSVQ GAYPPGSTFK MITAMAALEA GITNPEETVY CPGFLEVSNR
     RFHCWKRGGH GHMNLEESLE QSCDVYYYDV ALKVGIDRIS AMAEEFGLGV RHDIPMSAVA
     RGLAPNRDWK ARVHGQDWLV GDTANASIGQ GFMLASPLQL AVMTARIATG RKVAPRLVKS
     IDGVEQPSGA GEPLAVNQAN LRRLRKGMYA VSNNRRGTAY RSRILADDNR MAGKTGTSQV
     RNITAAERAA GVIRNEDLPW ERRDHALFVC FAPFDNPRFA VSVVVEHGGG GSTAAAPIAR
     DILLQALYDG FPPLESYPAK DRSRIEAQQE RLRRELRPVT RPEDKDRA
//

If you have problems or comments...

PBIL Back to PBIL home page