(data stored in ACNUC7421 zone)

SWISSPROT: YIDC_RUEPO

ID   YIDC_RUEPO              Reviewed;         609 AA.
AC   Q5LW11;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   08-MAY-2019, entry version 87.
DE   RecName: Full=Membrane protein insertase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE   AltName: Full=Foldase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE   AltName: Full=Membrane integrase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE   AltName: Full=Membrane protein YidC {ECO:0000255|HAMAP-Rule:MF_01810};
GN   Name=yidC {ECO:0000255|HAMAP-Rule:MF_01810};
GN   OrderedLocusNames=SPO0532;
OS   Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)
OS   (Silicibacter pomeroyi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Ruegeria.
OX   NCBI_TaxID=246200;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700808 / DSM 15171 / DSS-3;
RX   PubMed=15602564; DOI=10.1038/nature03170;
RA   Moran M.A., Buchan A., Gonzalez J.M., Heidelberg J.F., Whitman W.B.,
RA   Kiene R.P., Henriksen J.R., King G.M., Belas R., Fuqua C.,
RA   Brinkac L.M., Lewis M., Johri S., Weaver B., Pai G., Eisen J.A.,
RA   Rahe E., Sheldon W.M., Ye W., Miller T.R., Carlton J., Rasko D.A.,
RA   Paulsen I.T., Ren Q., Daugherty S.C., DeBoy R.T., Dodson R.J.,
RA   Durkin A.S., Madupu R., Nelson W.C., Sullivan S.A., Rosovitz M.J.,
RA   Haft D.H., Selengut J., Ward N.;
RT   "Genome sequence of Silicibacter pomeroyi reveals adaptations to the
RT   marine environment.";
RL   Nature 432:910-913(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 700808 / DSM 15171 / DSS-3;
RX   PubMed=25780504; DOI=10.1186/1944-3277-9-11;
RA   Rivers A.R., Smith C.B., Moran M.A.;
RT   "An updated genome annotation for the model marine bacterium Ruegeria
RT   pomeroyi DSS-3.";
RL   Stand. Genomic Sci. 9:11-11(2014).
CC   -!- FUNCTION: Required for the insertion and/or proper folding and/or
CC       complex formation of integral membrane proteins into the membrane.
CC       Involved in integration of membrane proteins that insert both
CC       dependently and independently of the Sec translocase complex, as
CC       well as at least some lipoproteins. Aids folding of multispanning
CC       membrane proteins. {ECO:0000255|HAMAP-Rule:MF_01810}.
CC   -!- SUBUNIT: Interacts with the Sec translocase complex via SecD.
CC       Specifically interacts with transmembrane segments of nascent
CC       integral membrane proteins during membrane integration.
CC       {ECO:0000255|HAMAP-Rule:MF_01810}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01810}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01810}.
CC   -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family. Type 1
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01810}.
DR   EMBL; CP000031; AAV93849.1; -; Genomic_DNA.
DR   RefSeq; WP_011046291.1; NC_003911.12.
DR   STRING; 246200.SPO0532; -.
DR   EnsemblBacteria; AAV93849; AAV93849; SPO0532.
DR   KEGG; sil:SPO0532; -.
DR   eggNOG; ENOG4105DHW; Bacteria.
DR   eggNOG; COG0706; LUCA.
DR   HOGENOM; HOG000101821; -.
DR   KO; K03217; -.
DR   OMA; INPVAGC; -.
DR   OrthoDB; 524437at2; -.
DR   BioCyc; RPOM246200:G1G48-539-MONOMER; -.
DR   Proteomes; UP000001023; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; ISS:TIGR.
DR   GO; GO:0032977; F:membrane insertase activity; IEA:InterPro.
DR   GO; GO:0008565; F:protein transporter activity; ISS:TIGR.
DR   GO; GO:0009306; P:protein secretion; ISS:TIGR.
DR   Gene3D; 2.70.98.90; -; 1.
DR   HAMAP; MF_01810; YidC_type1; 1.
DR   InterPro; IPR019998; Membr_insert_YidC.
DR   InterPro; IPR028055; Membr_insert_YidC/Oxa1_C.
DR   InterPro; IPR028053; Membr_insert_YidC_N.
DR   InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR   InterPro; IPR038210; YidC_periplasmic.
DR   InterPro; IPR038221; YidC_periplasmic_sf.
DR   PANTHER; PTHR12428; PTHR12428; 1.
DR   Pfam; PF02096; 60KD_IMP; 1.
DR   Pfam; PF14849; YidC_periplas; 1.
DR   PRINTS; PR00701; 60KDINNERMP.
DR   PRINTS; PR01900; YIDCPROTEIN.
DR   TIGRFAMs; TIGR03593; yidC_nterm; 1.
DR   TIGRFAMs; TIGR03592; yidC_oxa1_cterm; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q5LW11.
DR   SWISS-2DPAGE; Q5LW11.
KW   Cell inner membrane; Cell membrane; Chaperone; Complete proteome;
KW   Membrane; Protein transport; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN         1    609       Membrane protein insertase YidC.
FT                                /FTId=PRO_1000070179.
FT   TRANSMEM      8     28       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01810}.
FT   TRANSMEM    381    401       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01810}.
FT   TRANSMEM    451    471       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01810}.
FT   TRANSMEM    509    529       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01810}.
FT   TRANSMEM    545    565       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01810}.
SQ   SEQUENCE   609 AA;  66782 MW;  B88BAE40936AE27A CRC64;
     MDDQNKNLIL ATALSFLVIL VWFILFPPPE QTEAPATEIA TTNGTAVQTP TAAATEGGAG
     EVPALDSAAP TQAEAPRVQI DTPRLKGSVS LLGGRIDELS LKDYRVSLDE DAEIVEMLTP
     AGSTSAYYAL YGWAPGAGLN AADVPGPLTE WSLESGDTLS VGTPVTLSWS NGSGVTFRRT
     LAVDEDYMFT VTQSVENGSA APIGAAPYGI LARHGIGEDA DLPGLKNFFI LHEGVVAMND
     GTLSEIDYKD VRKFDIDPNE GAQAEVFQNK SDGWIGFTDH YWMATLIPGS GTAFKSAAKY
     DARRKIYQAE TVLPTMSVAP GESAEVTTRL FAGAKEWESI RAYQQDGVQK FLDSIDWGWF
     FFLTKPIFWL LHQINGLIGN MGWSIIGLTL IIKAIVFPLA LKSYVSMAKM KELQPQMEAL
     KEAAGDDRQK MQQGMMELYK KEKVNPAAGC LPILLQIPIF FSLYKVIFVT IELRQAPWFG
     PFRDLSMPDP TSIMNFFGWL PWAGPEAGSL TATILIGILP LLLGISMWLQ QKLNPAPTDP
     TQAMIFAWMP WVFMFMLGSF ASGLVVYWIA NNTITFTQQY IIMRSHGYKP DVFGNIKSGF
     ARRAKADKK
//

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