(data stored in ACNUC7421 zone)

SWISSPROT: Q5LVR8_RUEPO

ID   Q5LVR8_RUEPO            Unreviewed;       328 AA.
AC   Q5LVR8;
DT   01-FEB-2005, integrated into UniProtKB/TrEMBL.
DT   01-FEB-2005, sequence version 1.
DT   08-MAY-2019, entry version 91.
DE   SubName: Full=D-isomer specific 2-hydroxyacid dehydrogenase family protein {ECO:0000313|EMBL:AAV93940.1};
GN   OrderedLocusNames=SPO0632 {ECO:0000313|EMBL:AAV93940.1};
OS   Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3)
OS   (Silicibacter pomeroyi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Ruegeria.
OX   NCBI_TaxID=246200 {ECO:0000313|EMBL:AAV93940.1, ECO:0000313|Proteomes:UP000001023};
RN   [1] {ECO:0000313|EMBL:AAV93940.1, ECO:0000313|Proteomes:UP000001023}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700808 / DSM 15171 / DSS-3
RC   {ECO:0000313|Proteomes:UP000001023};
RX   PubMed=15602564; DOI=10.1038/nature03170;
RA   Moran M.A., Buchan A., Gonzalez J.M., Heidelberg J.F., Whitman W.B.,
RA   Kiene R.P., Henriksen J.R., King G.M., Belas R., Fuqua C., Brinkac L.,
RA   Lewis M., Johri S., Weaver B., Pai G., Eisen J.A., Rahe E.,
RA   Sheldon W.M., Ye W., Miller T.R., Carlton J., Rasko D.A.,
RA   Paulsen I.T., Ren Q., Daugherty S.C., Deboy R.T., Dodson R.J.,
RA   Durkin A.S., Madupu R., Nelson W.C., Sullivan S.A., Rosovitz M.J.,
RA   Haft D.H., Selengut J., Ward N.;
RT   "Genome sequence of Silicibacter pomeroyi reveals adaptations to the
RT   marine environment.";
RL   Nature 432:910-913(2004).
RN   [2] {ECO:0000313|EMBL:AAV93940.1, ECO:0000313|Proteomes:UP000001023}
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 700808 / DSM 15171 / DSS-3
RC   {ECO:0000313|Proteomes:UP000001023};
RX   PubMed=25780504; DOI=10.1186/1944-3277-9-11;
RA   Rivers A.R., Smith C.B., Moran M.A.;
RT   "An updated genome annotation for the model marine bacterium Ruegeria
RT   pomeroyi DSS-3.";
RL   Stand. Genomic Sci. 9:11-11(2014).
CC   -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC       dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
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DR   EMBL; CP000031; AAV93940.1; -; Genomic_DNA.
DR   RefSeq; WP_011046383.1; NC_003911.12.
DR   STRING; 246200.SPO0632; -.
DR   EnsemblBacteria; AAV93940; AAV93940; SPO0632.
DR   KEGG; sil:SPO0632; -.
DR   eggNOG; ENOG4105C5I; Bacteria.
DR   eggNOG; COG1052; LUCA.
DR   HOGENOM; HOG000136700; -.
DR   KO; K00015; -.
DR   OMA; YGAGVDH; -.
DR   OrthoDB; 1638924at2; -.
DR   BioCyc; RPOM246200:G1G48-643-MONOMER; -.
DR   Proteomes; UP000001023; Chromosome.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR   InterPro; IPR029753; D-isomer_DH_CS.
DR   InterPro; IPR029752; D-isomer_DH_CS1.
DR   InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF00389; 2-Hacid_dh; 1.
DR   Pfam; PF02826; 2-Hacid_dh_C; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00065; D_2_HYDROXYACID_DH_1; 1.
DR   PROSITE; PS00671; D_2_HYDROXYACID_DH_3; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q5LVR8.
DR   SWISS-2DPAGE; Q5LVR8.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001023};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU003719};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001023}.
FT   DOMAIN        8    323       2-Hacid_dh. {ECO:0000259|Pfam:PF00389}.
FT   DOMAIN      113    292       2-Hacid_dh_C. {ECO:0000259|Pfam:PF02826}.
SQ   SEQUENCE   328 AA;  36222 MW;  301877FE612F0748 CRC64;
     MPRERLSVVV TRRLPEVVET RLSELFNVRL RDDDTPMSRD ELAAALREAD VLVPTLNDRI
     DAGLLAQAGE RMRLIANYGA GVDHIDVATA RQRGILVSNT PGVLTDDTAD MTMALILAVT
     RRIPEGLAVM QKNEWTGWAP TALLGGRVGG RRLGILGMGR IGQAVARRAS AFGMQIHYHN
     RRRLRPEVED ALEATWWDSL DQMIARMDVI SVNCPSTPST FHLMNARRLK LMKPTGVIVN
     TSRGEVIDEN ALTRMIRTGE IAGAGLDVYE HGTQVNPRLR ELPNVVLLPH MGSATLEGRI
     EMGEKVIINI KTFADGHRPP DQVVPAML
//

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