(data stored in ACNUC7421 zone)

SWISSPROT: Q4ZZN3_PSEU2

ID   Q4ZZN3_PSEU2            Unreviewed;       203 AA.
AC   Q4ZZN3;
DT   07-JUN-2005, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2005, sequence version 1.
DT   08-MAY-2019, entry version 78.
DE   RecName: Full=5-formyltetrahydrofolate cyclo-ligase {ECO:0000256|RuleBase:RU361279};
DE            EC=6.3.3.2 {ECO:0000256|RuleBase:RU361279};
GN   OrderedLocusNames=Psyr_0317 {ECO:0000313|EMBL:AAY35389.1};
OS   Pseudomonas syringae pv. syringae (strain B728a).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas; Pseudomonas syringae.
OX   NCBI_TaxID=205918 {ECO:0000313|EMBL:AAY35389.1, ECO:0000313|Proteomes:UP000000426};
RN   [1] {ECO:0000313|EMBL:AAY35389.1, ECO:0000313|Proteomes:UP000000426}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B728a {ECO:0000313|EMBL:AAY35389.1,
RC   ECO:0000313|Proteomes:UP000000426};
RX   PubMed=16043691; DOI=10.1073/pnas.0504930102;
RA   Feil H., Feil W.S., Chain P., Larimer F., Dibartolo G., Copeland A.,
RA   Lykidis A., Trong S., Nolan M., Goltsman E., Thiel J., Malfatti S.,
RA   Loper J.E., Lapidus A., Detter J.C., Land M., Richardson P.M.,
RA   Kyrpides N.C., Ivanova N., Lindow S.E.;
RT   "Comparison of the complete genome sequences of Pseudomonas syringae
RT   pv. syringae B728a and pv. tomato DC3000.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:11064-11069(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=5-formyltetrahydrofolate + ATP = 5,10-
CC         methenyltetrahydrofolate + ADP + phosphate;
CC         Xref=Rhea:RHEA:10488, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:57455, ChEBI:CHEBI:57457, ChEBI:CHEBI:456216;
CC         EC=6.3.3.2; Evidence={ECO:0000256|RuleBase:RU361279};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|RuleBase:RU361279};
CC   -!- SIMILARITY: Belongs to the 5-formyltetrahydrofolate cyclo-ligase
CC       family. {ECO:0000256|RuleBase:RU361279}.
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DR   EMBL; CP000075; AAY35389.1; -; Genomic_DNA.
DR   RefSeq; WP_011266316.1; NC_007005.1.
DR   RefSeq; YP_233427.1; NC_007005.1.
DR   STRING; 205918.Psyr_0317; -.
DR   EnsemblBacteria; AAY35389; AAY35389; Psyr_0317.
DR   GeneID; 3365793; -.
DR   KEGG; psb:Psyr_0317; -.
DR   PATRIC; fig|205918.7.peg.319; -.
DR   eggNOG; ENOG4105MK2; Bacteria.
DR   eggNOG; COG0212; LUCA.
DR   HOGENOM; HOG000007300; -.
DR   KO; K01934; -.
DR   OMA; STIYPCQ; -.
DR   BioCyc; PSYR205918:G1G4J-318-MONOMER; -.
DR   Proteomes; UP000000426; Chromosome.
DR   GO; GO:0030272; F:5-formyltetrahydrofolate cyclo-ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.10420; -; 1.
DR   InterPro; IPR002698; FTHF_cligase.
DR   InterPro; IPR024185; FTHF_cligase-like_sf.
DR   InterPro; IPR037171; NagB/RpiA_transferase-like.
DR   PANTHER; PTHR23407:SF1; PTHR23407:SF1; 1.
DR   Pfam; PF01812; 5-FTHF_cyc-lig; 1.
DR   PIRSF; PIRSF006806; FTHF_cligase; 1.
DR   SUPFAM; SSF100950; SSF100950; 1.
DR   TIGRFAMs; TIGR02727; MTHFS_bact; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q4ZZN3.
DR   SWISS-2DPAGE; Q4ZZN3.
KW   ATP-binding {ECO:0000256|PIRSR:PIRSR006806-1,
KW   ECO:0000256|RuleBase:RU361279}; Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000426};
KW   Ligase {ECO:0000313|EMBL:AAY35389.1};
KW   Magnesium {ECO:0000256|RuleBase:RU361279};
KW   Metal-binding {ECO:0000256|RuleBase:RU361279};
KW   Nucleotide-binding {ECO:0000256|PIRSR:PIRSR006806-1,
KW   ECO:0000256|RuleBase:RU361279}.
FT   NP_BIND     140    148       ATP. {ECO:0000256|PIRSR:PIRSR006806-1}.
FT   COILED        9     29       {ECO:0000256|SAM:Coils}.
FT   BINDING      55     55       Substrate; via carbonyl oxygen.
FT                                {ECO:0000256|PIRSR:PIRSR006806-1}.
FT   BINDING      60     60       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR006806-1}.
SQ   SEQUENCE   203 AA;  23660 MW;  E1A86330605D9E75 CRC64;
     MISAQSLTRP QLRRQLRKAR KALSQSQQRA AARDIYRQLA QHPLFRRARH VSLYLPMDGE
     IDPRLLLREA QRRGKATYLP VLNAWPRTRM VFQRVRPGET FIPNRFRIPE PRIDRARQRP
     VWALDLILMP LVGFDDEGGR LGMGGGFYDR SLAYLARRKT WRKPLLLGLA HECQKVDRLA
     QASWDVPLHG TLSDKGWYVT QTL
//

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