(data stored in ACNUC7421 zone)

SWISSPROT: Q47TW2_THEFY

ID   Q47TW2_THEFY            Unreviewed;       696 AA.
AC   Q47TW2;
DT   13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT   13-SEP-2005, sequence version 1.
DT   08-MAY-2019, entry version 94.
DE   RecName: Full=DNA helicase {ECO:0000256|SAAS:SAAS00413339};
DE            EC=3.6.4.12 {ECO:0000256|SAAS:SAAS00413339};
GN   OrderedLocusNames=Tfu_0064 {ECO:0000313|EMBL:AAZ54102.1};
OS   Thermobifida fusca (strain YX).
OC   Bacteria; Actinobacteria; Streptosporangiales; Nocardiopsaceae;
OC   Thermobifida.
OX   NCBI_TaxID=269800 {ECO:0000313|EMBL:AAZ54102.1, ECO:0000313|Proteomes:UP000000434};
RN   [1] {ECO:0000313|Proteomes:UP000000434}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YX {ECO:0000313|Proteomes:UP000000434};
RX   PubMed=17209016; DOI=10.1128/JB.01899-06;
RA   Lykidis A., Mavromatis K., Ivanova N., Anderson I., Land M.,
RA   DiBartolo G., Martinez M., Lapidus A., Lucas S., Copeland A.,
RA   Richardson P., Wilson D.B., Kyrpides N.;
RT   "Genome sequence and analysis of the soil cellulolytic actinomycete
RT   Thermobifida fusca YX.";
RL   J. Bacteriol. 189:2477-2486(2007).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|SAAS:SAAS01129065};
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DR   EMBL; CP000088; AAZ54102.1; -; Genomic_DNA.
DR   RefSeq; WP_011290511.1; NC_007333.1.
DR   STRING; 269800.Tfu_0064; -.
DR   EnsemblBacteria; AAZ54102; AAZ54102; Tfu_0064.
DR   KEGG; tfu:Tfu_0064; -.
DR   eggNOG; ENOG41064YA; Bacteria.
DR   eggNOG; COG0210; LUCA.
DR   HOGENOM; HOG000006338; -.
DR   OMA; SHQRIYG; -.
DR   OrthoDB; 137860at2; -.
DR   BioCyc; TFUS269800:G1G4Q-64-MONOMER; -.
DR   Proteomes; UP000000434; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070; PTHR11070; 2.
DR   Pfam; PF13361; UvrD_C; 2.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
DR   PRODOM; Q47TW2.
DR   SWISS-2DPAGE; Q47TW2.
KW   ATP-binding {ECO:0000256|SAAS:SAAS00146071};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000434};
KW   DNA-binding {ECO:0000256|SAAS:SAAS00745286};
KW   Helicase {ECO:0000256|SAAS:SAAS00553650, ECO:0000313|EMBL:AAZ54102.1};
KW   Hydrolase {ECO:0000256|SAAS:SAAS00146062};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS00145996};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000434}.
FT   DOMAIN      240    509       UvrD-like helicase ATP-binding.
FT                                {ECO:0000259|PROSITE:PS51198}.
SQ   SEQUENCE   696 AA;  77583 MW;  62F4089A71FBE085 CRC64;
     MARLAIDRDF LLDFAKLEKS VQDRVTEVFT KFEHARHTGI HLEKIANARD DRFRTIRIDQ
     FWRGVVLAPE AGDIYTLLKV LPHDDAYAWA QRRTATVNGA TGRIEIRDVE AIDASLPHLE
     QVAQDAPRRL FDHVSDSDLR RLGIDGQTLA FARVLTDEAQ LEAAEGLLPS VQWKVLTALA
     AGYTPEEAWD ELCVDITSEQ IDPDDLDAAV ERSRDRVVFV DGPDELLSVL AYPFALWRVY
     LHPVQRSVVE ASYRGPARIT GGPGTGKTVV ALHRARHLAR TGEGKVLVTT FTSTLAESLR
     AGLMLLDDYD EFVDRIDVAH VDQLAHRIVR EEHGALRMLT GAQERELWST IIRDLGLSFT
     PAFLAEEWRQ VVIAQQVRSA QDYLAAKRTG RGRPLGSQQR AHVWQAIWEF EAALREQGLW
     THETVCVEAA RLLAERDRKP YRHIVVDEAQ DLSPEKWRLL RAAVSEGPND LFFAADTHQR
     IYQHQVTLRD VGITIAGRST RLRINYRTTA EILAWSLGLL HGERIDDMDG GVESITGCRS
     ELHGPPPTVQ GFASKEDELC AVAAAVREWM DSGVAPEEIG VAVRSNRLVK EVAETLNAES
     IPVRELAGGL PEDGAVSVGT MHRMKGLEFR CLVVAGVSEG QLPALKAVVP ESEDKAAHRA
     GLQRERCLLF VACTRAREQL LVTWSCEPSP FLTALS
//

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