(data stored in ACNUC7421 zone)

SWISSPROT: CH601_THEFY

ID   CH601_THEFY             Reviewed;         541 AA.
AC   Q47TE8;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   08-MAY-2019, entry version 96.
DE   RecName: Full=60 kDa chaperonin 1 {ECO:0000255|HAMAP-Rule:MF_00600};
DE   AltName: Full=GroEL protein 1 {ECO:0000255|HAMAP-Rule:MF_00600};
DE   AltName: Full=Protein Cpn60 1 {ECO:0000255|HAMAP-Rule:MF_00600};
GN   Name=groL1 {ECO:0000255|HAMAP-Rule:MF_00600};
GN   Synonyms=groEL1 {ECO:0000255|HAMAP-Rule:MF_00600};
GN   OrderedLocusNames=Tfu_0228;
OS   Thermobifida fusca (strain YX).
OC   Bacteria; Actinobacteria; Streptosporangiales; Nocardiopsaceae;
OC   Thermobifida.
OX   NCBI_TaxID=269800;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YX;
RX   PubMed=17209016; DOI=10.1128/JB.01899-06;
RA   Lykidis A., Mavromatis K., Ivanova N., Anderson I., Land M.,
RA   DiBartolo G., Martinez M., Lapidus A., Lucas S., Copeland A.,
RA   Richardson P., Wilson D.B., Kyrpides N.;
RT   "Genome sequence and analysis of the soil cellulolytic actinomycete
RT   Thermobifida fusca YX.";
RL   J. Bacteriol. 189:2477-2486(2007).
CC   -!- FUNCTION: Prevents misfolding and promotes the refolding and
CC       proper assembly of unfolded polypeptides generated under stress
CC       conditions. {ECO:0000255|HAMAP-Rule:MF_00600}.
CC   -!- SUBUNIT: Oligomer of 14 subunits composed of two stacked rings of
CC       7 subunits. {ECO:0000255|HAMAP-Rule:MF_00600}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00600}.
CC   -!- SIMILARITY: Belongs to the chaperonin (HSP60) family.
CC       {ECO:0000255|HAMAP-Rule:MF_00600}.
DR   EMBL; CP000088; AAZ54266.1; -; Genomic_DNA.
DR   RefSeq; WP_011290675.1; NC_007333.1.
DR   SMR; Q47TE8; -.
DR   STRING; 269800.Tfu_0228; -.
DR   PRIDE; Q47TE8; -.
DR   EnsemblBacteria; AAZ54266; AAZ54266; Tfu_0228.
DR   KEGG; tfu:Tfu_0228; -.
DR   eggNOG; ENOG4105CJ9; Bacteria.
DR   eggNOG; COG0459; LUCA.
DR   HOGENOM; HOG000076290; -.
DR   KO; K04077; -.
DR   OMA; TDTDKME; -.
DR   OrthoDB; 265347at2; -.
DR   BioCyc; TFUS269800:G1G4Q-234-MONOMER; -.
DR   Proteomes; UP000000434; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0042026; P:protein refolding; IEA:UniProtKB-UniRule.
DR   CDD; cd03344; GroEL; 1.
DR   Gene3D; 1.10.560.10; -; 1.
DR   Gene3D; 3.30.260.10; -; 1.
DR   Gene3D; 3.50.7.10; -; 1.
DR   HAMAP; MF_00600; CH60; 1.
DR   InterPro; IPR018370; Chaperonin_Cpn60_CS.
DR   InterPro; IPR001844; Chaprnin_Cpn60.
DR   InterPro; IPR002423; Cpn60/TCP-1.
DR   InterPro; IPR027409; GroEL-like_apical_dom_sf.
DR   InterPro; IPR027413; GROEL-like_equatorial_sf.
DR   InterPro; IPR027410; TCP-1-like_intermed_sf.
DR   Pfam; PF00118; Cpn60_TCP1; 1.
DR   PRINTS; PR00298; CHAPERONIN60.
DR   SUPFAM; SSF48592; SSF48592; 1.
DR   SUPFAM; SSF52029; SSF52029; 1.
DR   SUPFAM; SSF54849; SSF54849; 1.
DR   TIGRFAMs; TIGR02348; GroEL; 1.
DR   PROSITE; PS00296; CHAPERONINS_CPN60; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q47TE8.
DR   SWISS-2DPAGE; Q47TE8.
KW   ATP-binding; Chaperone; Complete proteome; Cytoplasm;
KW   Nucleotide-binding; Reference proteome.
FT   CHAIN         1    541       60 kDa chaperonin 1.
FT                                /FTId=PRO_0000257013.
SQ   SEQUENCE   541 AA;  57523 MW;  4DB3DE47EC7AACF2 CRC64;
     MAAKLIAFDE EARRGLERGM NQLADAVKVT LGPKGRNVVL EKKWGAPTIT NDGVSIAKEI
     ELEDPYEKIG AELVKEVAKK TDDVAGDGTT TATVLAQALV REGLRNVAAG ANPIGLKRGI
     DAAVARISEE LANLSKEVET KEQIASTASI SAGDPQIGEY IAEAMDKVGK EGVITVEEGQ
     TFGLELELAE GMRFDKGYIS PYFATDLERM ETVLEDPYIL IANQKISNNN EFLPVIEKVL
     QAGRPLVVIA EDVEGTALQT LVVNKIRGTF KSVAIKAPGF GDRRKAMLQD IAILTGGQVI
     TEEVGLKLEN TELDMLGRAR KVVVTKDETT IVDGAGDASA IAGRVNEIRA EIERTDSDYD
     REKLQERLAR LAGGVAVIKA GAATEVELKE RKHRIEDAVR NAKAAVEEGI LPGGGVALLQ
     ASIAAFEKLE LEGDEAIGAS IVRRAVEEPL KQIAINAGYE GGVVVEKVKS LEPGIGLNAA
     TGEYTDLFKD GVIDPTKVTR SALQNAASIA GLFLTTEAVI AEKPEKPAAN NAGGDMGGMD
     F
//

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