SWISSPROT: Q47SH4_THEFY

ID   Q47SH4_THEFY            Unreviewed;       521 AA.
AC   Q47SH4;
DT   13-SEP-2005, integrated into UniProtKB/TrEMBL.
DT   13-SEP-2005, sequence version 1.
DT   08-MAY-2019, entry version 107.
DE   SubName: Full=Signal transduction histidine kinase {ECO:0000313|EMBL:AAZ54593.1};
DE            EC=2.7.3.- {ECO:0000313|EMBL:AAZ54593.1};
GN   OrderedLocusNames=Tfu_0555 {ECO:0000313|EMBL:AAZ54593.1};
OS   Thermobifida fusca (strain YX).
OC   Bacteria; Actinobacteria; Streptosporangiales; Nocardiopsaceae;
OC   Thermobifida.
OX   NCBI_TaxID=269800 {ECO:0000313|EMBL:AAZ54593.1, ECO:0000313|Proteomes:UP000000434};
RN   [1] {ECO:0000313|Proteomes:UP000000434}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YX {ECO:0000313|Proteomes:UP000000434};
RX   PubMed=17209016; DOI=10.1128/JB.01899-06;
RA   Lykidis A., Mavromatis K., Ivanova N., Anderson I., Land M.,
RA   DiBartolo G., Martinez M., Lapidus A., Lucas S., Copeland A.,
RA   Richardson P., Wilson D.B., Kyrpides N.;
RT   "Genome sequence and analysis of the soil cellulolytic actinomycete
RT   Thermobifida fusca YX.";
RL   J. Bacteriol. 189:2477-2486(2007).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3;
CC         Evidence={ECO:0000256|SAAS:SAAS01118672};
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DR   EMBL; CP000088; AAZ54593.1; -; Genomic_DNA.
DR   RefSeq; WP_011291002.1; NC_007333.1.
DR   STRING; 269800.Tfu_0555; -.
DR   EnsemblBacteria; AAZ54593; AAZ54593; Tfu_0555.
DR   KEGG; tfu:Tfu_0555; -.
DR   eggNOG; ENOG4105RAK; Bacteria.
DR   eggNOG; COG3920; LUCA.
DR   HOGENOM; HOG000247643; -.
DR   KO; K00936; -.
DR   OMA; GSIAIVH; -.
DR   OrthoDB; 1755994at2; -.
DR   BioCyc; TFUS269800:G1G4Q-566-MONOMER; -.
DR   Proteomes; UP000000434; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR   CDD; cd00075; HATPase_c; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.450.280; -; 1.
DR   Gene3D; 3.30.565.10; -; 1.
DR   InterPro; IPR022066; H_kinase_N.
DR   InterPro; IPR038424; H_kinase_N_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   InterPro; IPR011495; Sig_transdc_His_kin_sub2_dim/P.
DR   InterPro; IPR011102; Sig_transdc_His_kinase_HWE.
DR   Pfam; PF12282; H_kinase_N; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF07568; HisKA_2; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00911; HWE_HK; 1.
DR   SUPFAM; SSF55785; SSF55785; 1.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
PE   4: Predicted;
DR   PRODOM; Q47SH4.
DR   SWISS-2DPAGE; Q47SH4.
KW   ATP-binding {ECO:0000256|SAAS:SAAS00925949};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000434};
KW   Kinase {ECO:0000256|SAAS:SAAS01003914, ECO:0000313|EMBL:AAZ54593.1};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS00925310};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000434};
KW   Transferase {ECO:0000256|SAAS:SAAS01003669,
KW   ECO:0000313|EMBL:AAZ54593.1}.
FT   DOMAIN      309    515       Histidine kinase. {ECO:0000259|PROSITE:
FT                                PS50109}.
SQ   SEQUENCE   521 AA;  57292 MW;  E16ECD56C9EECA30 CRC64;
     MPHLSDLIRR YTALSTADLE WLHALVSDWQ LLADLSFADL LLWTRLREDN GWIAVAQMRP
     TTGPTAYQDD LVETILYDAP ATPGEEDPVP PPMRSKRALI DRAWREGRVC REGDPDWSGG
     VPVREETIPV RREGTMVAVI QRSTNLSAAR TPSRLELTYL QSASDLAQMI AEGSFPFSDQ
     GPLMVRSPRV GDGLLRLDRE GRVIYASPNA LSAYRRLGLA TDLVGTSLAR TTVELADDPD
     PRDESLSWTA GGRVPLEAEV EARGTTVQLR AIPLIVGGER IGALVMVRDV TELRRREREL
     MTKDATIREI HHRVKNNLQT VAALLRLQAR RLQNPEGRAA LEEAVRRVGS IAIVHEMLSH
     TPDETVDFDD IADRVIEMAA EVSSTDKAVV GLRRVGNFGM LSALVATPLS MVLAELVQNA
     VEHGLEYGPG TIEVRVRRQA PAPGPDDGRR STGRLIIEVV DNGTGLPADF DLETSSSLGL
     QIVRTLVTGE LAGRMEMTPQ EGGGTKVLLD LPVDHEVQYY N
//