(data stored in ACNUC7421 zone)

SWISSPROT: THIQ_SHISS

ID   THIQ_SHISS              Reviewed;         232 AA.
AC   Q3Z5U5;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   27-SEP-2005, sequence version 1.
DT   08-MAY-2019, entry version 97.
DE   RecName: Full=Thiamine import ATP-binding protein ThiQ {ECO:0000255|HAMAP-Rule:MF_01723};
DE            EC=3.6.3.- {ECO:0000255|HAMAP-Rule:MF_01723};
GN   Name=thiQ {ECO:0000255|HAMAP-Rule:MF_01723};
GN   OrderedLocusNames=SSON_0072;
OS   Shigella sonnei (strain Ss046).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=300269;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ss046;
RX   PubMed=16275786; DOI=10.1093/nar/gki954;
RA   Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X.,
RA   Wang J., Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S.,
RA   Nie H., Peng J., Xu J., Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y.,
RA   Qiang B., Hou Y., Yu J., Jin Q.;
RT   "Genome dynamics and diversity of Shigella species, the etiologic
RT   agents of bacillary dysentery.";
RL   Nucleic Acids Res. 33:6445-6458(2005).
CC   -!- FUNCTION: Part of the ABC transporter complex ThiBPQ involved in
CC       thiamine import. Responsible for energy coupling to the transport
CC       system. {ECO:0000255|HAMAP-Rule:MF_01723}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins
CC       (ThiQ), two transmembrane proteins (ThiP) and a solute-binding
CC       protein (ThiB). {ECO:0000255|HAMAP-Rule:MF_01723}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01723}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01723}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Thiamine
CC       importer (TC 3.A.1.19.1) family. {ECO:0000255|HAMAP-
CC       Rule:MF_01723}.
DR   EMBL; CP000038; AAZ86867.1; -; Genomic_DNA.
DR   SMR; Q3Z5U5; -.
DR   EnsemblBacteria; AAZ86867; AAZ86867; SSON_0072.
DR   KEGG; ssn:SSON_0072; -.
DR   KO; K02062; -.
DR   OMA; TSHYPSE; -.
DR   BioCyc; SSON300269:G1GL2-82-MONOMER; -.
DR   Proteomes; UP000002529; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0048502; F:thiamine-transporting ATPase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0071934; P:thiamine transmembrane transport; IEA:InterPro.
DR   GO; GO:0015888; P:thiamine transport; IEA:UniProtKB-UniRule.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like.
DR   InterPro; IPR017871; ABC_transporter_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005968; Thiamine_ABC_ThiQ.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01277; thiQ; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51288; THIQ; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q3Z5U5.
DR   SWISS-2DPAGE; Q3Z5U5.
KW   ATP-binding; Cell inner membrane; Cell membrane; Complete proteome;
KW   Hydrolase; Membrane; Nucleotide-binding; Transport.
FT   CHAIN         1    232       Thiamine import ATP-binding protein ThiQ.
FT                                /FTId=PRO_0000274462.
FT   DOMAIN        2    230       ABC transporter. {ECO:0000255|HAMAP-
FT                                Rule:MF_01723}.
FT   NP_BIND      32     39       ATP. {ECO:0000255|HAMAP-Rule:MF_01723}.
SQ   SEQUENCE   232 AA;  25041 MW;  82AD24A7E1BA1423 CRC64;
     MLKLTDITWL YHHLPMRFSL TVERGEQVAI LGPSGAGKST LLNLIAGFLT PASGSLTIDS
     VDHTTTPPSR RPVSMLFQEN NLFSHLTVAQ NIGLGLNPGL KLNAAQQEKM HAIARQMGID
     NLMARLPGEL SGGQRQRVAL ARCLVREQPI LLLDEPFSAL DPALRQEMLT LVSTSCQQQK
     MTLLMVSHSV EDAARIATRS VVVADGRIAW QGKTDELLSG KASASALLGI TG
//

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