(data stored in ACNUC7421 zone)

SWISSPROT: MRAZ_SHISS

ID   MRAZ_SHISS              Reviewed;         152 AA.
AC   Q3Z5S8;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   27-SEP-2005, sequence version 1.
DT   08-MAY-2019, entry version 83.
DE   RecName: Full=Transcriptional regulator MraZ;
GN   Name=mraZ {ECO:0000255|HAMAP-Rule:MF_01008};
GN   OrderedLocusNames=SSON_0089;
OS   Shigella sonnei (strain Ss046).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=300269;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ss046;
RX   PubMed=16275786; DOI=10.1093/nar/gki954;
RA   Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X.,
RA   Wang J., Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S.,
RA   Nie H., Peng J., Xu J., Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y.,
RA   Qiang B., Hou Y., Yu J., Jin Q.;
RT   "Genome dynamics and diversity of Shigella species, the etiologic
RT   agents of bacillary dysentery.";
RL   Nucleic Acids Res. 33:6445-6458(2005).
CC   -!- FUNCTION: Negatively regulates its own expression and that of the
CC       subsequent genes in the proximal part of the division and cell
CC       wall (dcw) gene cluster. Acts by binding directly to DNA. May also
CC       regulate the expression of genes outside the dcw cluster.
CC       {ECO:0000255|HAMAP-Rule:MF_01008}.
CC   -!- SUBUNIT: Forms oligomers. {ECO:0000255|HAMAP-Rule:MF_01008}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC       Rule:MF_01008}.
CC   -!- SIMILARITY: Belongs to the MraZ family. {ECO:0000255|HAMAP-
CC       Rule:MF_01008}.
DR   EMBL; CP000038; AAZ86884.1; -; Genomic_DNA.
DR   EnsemblBacteria; AAZ86884; AAZ86884; SSON_0089.
DR   KEGG; ssn:SSON_0089; -.
DR   HOGENOM; HOG000283907; -.
DR   KO; K03925; -.
DR   OMA; RGQERCL; -.
DR   BioCyc; SSON300269:G1GL2-103-MONOMER; -.
DR   Proteomes; UP000002529; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR   GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   CDD; cd16321; MraZ_C; 1.
DR   CDD; cd16320; MraZ_N; 1.
DR   Gene3D; 2.40.330.20; -; 1.
DR   HAMAP; MF_01008; MraZ; 1.
DR   InterPro; IPR003444; MraZ.
DR   InterPro; IPR035644; MraZ_C.
DR   InterPro; IPR020603; MraZ_dom.
DR   InterPro; IPR035642; MraZ_N.
DR   InterPro; IPR038619; MraZ_sf.
DR   InterPro; IPR007159; SpoVT-AbrB_dom.
DR   InterPro; IPR037914; SpoVT-AbrB_sf.
DR   PANTHER; PTHR34701; PTHR34701; 1.
DR   Pfam; PF02381; MraZ; 2.
DR   ProDom; PD006745; MraZ; 1.
DR   SUPFAM; SSF89447; SSF89447; 1.
DR   TIGRFAMs; TIGR00242; TIGR00242; 1.
DR   PROSITE; PS51740; SPOVT_ABRB; 2.
PE   3: Inferred from homology;
DR   PRODOM; Q3Z5S8.
DR   SWISS-2DPAGE; Q3Z5S8.
KW   Complete proteome; Cytoplasm; DNA-binding; Repeat; Repressor;
KW   Transcription; Transcription regulation.
FT   CHAIN         1    152       Transcriptional regulator MraZ.
FT                                /FTId=PRO_0000230110.
FT   DOMAIN        5     52       SpoVT-AbrB 1. {ECO:0000255|PROSITE-
FT                                ProRule:PRU01076}.
FT   DOMAIN       81    124       SpoVT-AbrB 2. {ECO:0000255|PROSITE-
FT                                ProRule:PRU01076}.
SQ   SEQUENCE   152 AA;  17388 MW;  482F6D802BEDC772 CRC64;
     MFRGATLVNL DSKGRLSVPT RYREQLLENA VGQMVCTIDI HHPCLLLYPL PEWEIIEQKL
     SRLSSMNPVE RRVQRLLLGH ASECQMDGAG RLLIAPVLRQ HAGLTKEVML VGQFNKFELW
     DETTWHQQVK EDIDAEQLAT GDLSERLQDL SL
//

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