(data stored in ACNUC7421 zone)

SWISSPROT: Q3Z5Q1_SHISS

ID   Q3Z5Q1_SHISS            Unreviewed;       297 AA.
AC   Q3Z5Q1;
DT   27-SEP-2005, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2005, sequence version 1.
DT   08-MAY-2019, entry version 83.
DE   SubName: Full=Quinolinate phosphoribosyltransferase {ECO:0000313|EMBL:AAZ86911.1};
GN   Name=nadC {ECO:0000313|EMBL:AAZ86911.1};
GN   OrderedLocusNames=SSON_0117 {ECO:0000313|EMBL:AAZ86911.1};
OS   Shigella sonnei (strain Ss046).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=300269 {ECO:0000313|EMBL:AAZ86911.1, ECO:0000313|Proteomes:UP000002529};
RN   [1] {ECO:0000313|EMBL:AAZ86911.1, ECO:0000313|Proteomes:UP000002529}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ss046 {ECO:0000313|EMBL:AAZ86911.1,
RC   ECO:0000313|Proteomes:UP000002529};
RX   PubMed=16275786; DOI=10.1093/nar/gki954;
RA   Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X.,
RA   Wang J., Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S.,
RA   Nie H., Peng J., Xu J., Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y.,
RA   Qiang B., Hou Y., Yu J., Jin Q.;
RT   "Genome dynamics and diversity of Shigella species, the etiologic
RT   agents of bacillary dysentery.";
RL   Nucleic Acids Res. 33:6445-6458(2005).
CC   -!- SIMILARITY: Belongs to the NadC/ModD family.
CC       {ECO:0000256|PIRNR:PIRNR006250}.
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DR   EMBL; CP000038; AAZ86911.1; -; Genomic_DNA.
DR   EnsemblBacteria; AAZ86911; AAZ86911; SSON_0117.
DR   KEGG; ssn:SSON_0117; -.
DR   HOGENOM; HOG000224022; -.
DR   KO; K00767; -.
DR   OMA; CGGCHNH; -.
DR   BioCyc; SSON300269:G1GL2-131-MONOMER; -.
DR   Proteomes; UP000002529; Chromosome.
DR   GO; GO:0004514; F:nicotinate-nucleotide diphosphorylase (carboxylating) activity; IEA:InterPro.
DR   GO; GO:0009435; P:NAD biosynthetic process; IEA:InterPro.
DR   CDD; cd01572; QPRTase; 1.
DR   Gene3D; 3.20.20.70; -; 1.
DR   Gene3D; 3.90.1170.20; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR004393; NadC.
DR   InterPro; IPR027277; NadC/ModD.
DR   InterPro; IPR036068; Nicotinate_pribotase-like_C.
DR   InterPro; IPR037128; Quinolinate_PRibosylTase_N_sf.
DR   InterPro; IPR002638; Quinolinate_PRibosylTrfase_C.
DR   InterPro; IPR022412; Quinolinate_PRibosylTrfase_N.
DR   PANTHER; PTHR32179; PTHR32179; 1.
DR   Pfam; PF01729; QRPTase_C; 1.
DR   Pfam; PF02749; QRPTase_N; 1.
DR   PIRSF; PIRSF006250; NadC_ModD; 1.
DR   SUPFAM; SSF51690; SSF51690; 1.
DR   TIGRFAMs; TIGR00078; nadC; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q3Z5Q1.
DR   SWISS-2DPAGE; Q3Z5Q1.
KW   Complete proteome {ECO:0000313|Proteomes:UP000002529};
KW   Glycosyltransferase {ECO:0000256|PIRNR:PIRNR006250,
KW   ECO:0000313|EMBL:AAZ86911.1};
KW   Transferase {ECO:0000256|PIRNR:PIRNR006250,
KW   ECO:0000313|EMBL:AAZ86911.1}.
FT   DOMAIN       43    129       QRPTase_N. {ECO:0000259|Pfam:PF02749}.
FT   DOMAIN      131    295       QRPTase_C. {ECO:0000259|Pfam:PF01729}.
FT   REGION      152    154       Substrate binding. {ECO:0000256|PIRSR:
FT                                PIRSR006250-1}.
FT   REGION      259    261       Substrate binding. {ECO:0000256|PIRSR:
FT                                PIRSR006250-1}.
FT   REGION      280    282       Substrate binding. {ECO:0000256|PIRSR:
FT                                PIRSR006250-1}.
FT   BINDING     119    119       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR006250-1}.
FT   BINDING     176    176       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR006250-1}.
FT   BINDING     186    186       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR006250-1}.
FT   BINDING     215    215       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR006250-1}.
FT   BINDING     236    236       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR006250-1}.
SQ   SEQUENCE   297 AA;  32746 MW;  C8850536963744E2 CRC64;
     MPPRRYNPDT RRDELLERIN LDIPGAVAQA LREDLGGTVD ANNDITAKLL PENSRSHATV
     STRENGVFCG KRWVEEVFIQ LAGDDVTIIW HVDDGDVINA NQPLFELEGP SRVLLTGERT
     ALNFVQTLSG VASKVRHYVE LLEGTNTQLL DTRKTLPGLR SALKYAVLCG GGANHRLGLS
     DAFLIKENHI IASGSVRQAV EKASWLHPDA PVEVEVENLE ELDEALKAGA DIIMLDNFET
     EQMREAVKRT NGKALLEVSG NVTDKTLREF AETGVDFISV GALTKHVQAL DLSMRFR
//

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