(data stored in ACNUC7421 zone)

SWISSPROT: Q2IM45_ANADE

ID   Q2IM45_ANADE            Unreviewed;       797 AA.
AC   Q2IM45;
DT   07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   07-MAR-2006, sequence version 1.
DT   08-MAY-2019, entry version 93.
DE   RecName: Full=DNA helicase {ECO:0000256|SAAS:SAAS00413339};
DE            EC=3.6.4.12 {ECO:0000256|SAAS:SAAS00413339};
GN   OrderedLocusNames=Adeh_0097 {ECO:0000313|EMBL:ABC79874.1};
OS   Anaeromyxobacter dehalogenans (strain 2CP-C).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Anaeromyxobacteraceae; Anaeromyxobacter.
OX   NCBI_TaxID=290397 {ECO:0000313|EMBL:ABC79874.1, ECO:0000313|Proteomes:UP000001935};
RN   [1] {ECO:0000313|EMBL:ABC79874.1, ECO:0000313|Proteomes:UP000001935}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2CP-C {ECO:0000313|EMBL:ABC79874.1,
RC   ECO:0000313|Proteomes:UP000001935};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C.,
RA   Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Anderson I., Sanford R.A., Ritalahti K.M., Thomas H.S.,
RA   Kirby J.R., Zhulin I.B., Loeffler F.E., Richardson P.;
RT   "Complete sequence of Anaeromyxobacter dehalogenans 2CP-C.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000001935}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2CP-C {ECO:0000313|Proteomes:UP000001935};
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C.,
RA   Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Anderson I., Sanford R.A., Ritalahti K.M., Thomas H.S.,
RA   Kirby J.R., Zhulin I.B., Loeffler F.E., Richardson P.;
RT   "Complete sequence of Anaeromyxobacter dehalogenans 2CP-C.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|SAAS:SAAS01129065};
CC   -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC       {ECO:0000256|SAAS:SAAS00709641}.
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DR   EMBL; CP000251; ABC79874.1; -; Genomic_DNA.
DR   RefSeq; WP_011419157.1; NC_007760.1.
DR   STRING; 290397.Adeh_0097; -.
DR   EnsemblBacteria; ABC79874; ABC79874; Adeh_0097.
DR   KEGG; ade:Adeh_0097; -.
DR   eggNOG; ENOG4105C4R; Bacteria.
DR   eggNOG; COG0210; LUCA.
DR   HOGENOM; HOG000033016; -.
DR   KO; K03657; -.
DR   OMA; APIQTFH; -.
DR   BioCyc; ADEH290397:G1G5W-101-MONOMER; -.
DR   Proteomes; UP000001935; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.10.160; -; 1.
DR   InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   InterPro; IPR034739; UvrD/AddA_N.
DR   PANTHER; PTHR11070; PTHR11070; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR   PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q2IM45.
DR   SWISS-2DPAGE; Q2IM45.
KW   ATP-binding {ECO:0000256|SAAS:SAAS00146071};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001935};
KW   DNA-binding {ECO:0000256|SAAS:SAAS00745286};
KW   Helicase {ECO:0000256|SAAS:SAAS00553650, ECO:0000313|EMBL:ABC79874.1};
KW   Hydrolase {ECO:0000256|SAAS:SAAS00146062};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS00145996};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001935}.
FT   DOMAIN       14    294       UvrD-like helicase ATP-binding.
FT                                {ECO:0000259|PROSITE:PS51198}.
FT   DOMAIN      295    580       UvrD-like helicase C-terminal.
FT                                {ECO:0000259|PROSITE:PS51217}.
SQ   SEQUENCE   797 AA;  87447 MW;  0C38870C4E1641B3 CRC64;
     MGYLPAPVAE DLLQDLNDAQ REAVLHDDGP LLVLAGAGSG KTRVIVHRIA RLVRDRGVVP
     WHVLAVTFTN KAAGEMRERL ERLLGPLARE LWVQTFHAFG ARFLRREAAR AGLPPSFAIY
     DDDDQLRLVK RILAEVGLDE AEGLTPRRVL SQIDRWKNQA LRAAEVKVAG LDPDAARSKE
     VYHRYEQALS RAGAVDFGDL LLRPVRLLEE DAALRARWAG RFRYLLVDEF QDTNPVQYRL
     LQLLTGPRRN VCVVGDDDQA IYRWRGADVS NILGFDGDFP GAKVVKLEQN YRSTRTILDA
     AHAVISRARR RREKRLWTES GAGAPLALLV GEDEGAEAER IARAVAAERG RGTSGDEIAV
     LYRTNAQSRP LEAAMRAARI PYVIVRGTSF YERAEVRDAA AYLRLALSPA SDLDLERVVN
     RPPRGIGEKT VERLRAHAAA RGVPLVEAVA ERDAVAELKP AARRALAEFH DLVTGLAADV
     PALDAGVAVQ EVLKRSGMLS RLEEEHTDEA VERAENLAEL VAAAREFDES IAGEPPPGDP
     DEVRPPPLAR FLEQIALLGE ADAATPEGRV ALMTLHAAKG LEFEAVFLAG MEDGTLPYER
     PWADQTASER DESLDEERRL CYVGMTRAKR RLTLSLARRR IGYGESGPSY RNMEPSRFLR
     DLPPELFGDA VAREVRAREA AQAAAVARPP TIRRLPGALE GEPHIELDGD DLPRAPASAP
     RARPAAPRGE PTVDYSFDQR GDAGAAAFSR GERVAHASLG EGVVLACEAG GADAKATVRF
     ASVGDKRVLA RFLRRAF
//

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