(data stored in ACNUC7421 zone)

SWISSPROT: Q2IMK2_ANADE

ID   Q2IMK2_ANADE            Unreviewed;       244 AA.
AC   Q2IMK2;
DT   07-MAR-2006, integrated into UniProtKB/TrEMBL.
DT   07-MAR-2006, sequence version 1.
DT   08-MAY-2019, entry version 70.
DE   RecName: Full=1-acyl-sn-glycerol-3-phosphate acyltransferase {ECO:0000256|RuleBase:RU361267};
DE            EC=2.3.1.51 {ECO:0000256|RuleBase:RU361267};
GN   OrderedLocusNames=Adeh_0255 {ECO:0000313|EMBL:ABC80031.1};
OS   Anaeromyxobacter dehalogenans (strain 2CP-C).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Anaeromyxobacteraceae; Anaeromyxobacter.
OX   NCBI_TaxID=290397 {ECO:0000313|EMBL:ABC80031.1, ECO:0000313|Proteomes:UP000001935};
RN   [1] {ECO:0000313|Proteomes:UP000001935}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2CP-C {ECO:0000313|Proteomes:UP000001935};
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C.,
RA   Tapia R., Gilna P., Kiss H., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Anderson I., Sanford R.A., Ritalahti K.M., Thomas H.S.,
RA   Kirby J.R., Zhulin I.B., Loeffler F.E., Richardson P.;
RT   "Complete sequence of Anaeromyxobacter dehalogenans 2CP-C.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-
CC         diacyl-sn-glycero-3-phosphate + CoA; Xref=Rhea:RHEA:19709,
CC         ChEBI:CHEBI:57287, ChEBI:CHEBI:57970, ChEBI:CHEBI:58342,
CC         ChEBI:CHEBI:58608; EC=2.3.1.51;
CC         Evidence={ECO:0000256|RuleBase:RU361267};
CC   -!- DOMAIN: The HXXXXD motif is essential for acyltransferase activity
CC       and may constitute the binding site for the phosphate moiety of
CC       the glycerol-3-phosphate. {ECO:0000256|RuleBase:RU361267}.
CC   -!- SIMILARITY: Belongs to the 1-acyl-sn-glycerol-3-phosphate
CC       acyltransferase family. {ECO:0000256|RuleBase:RU361267}.
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DR   EMBL; CP000251; ABC80031.1; -; Genomic_DNA.
DR   RefSeq; WP_011419314.1; NC_007760.1.
DR   STRING; 290397.Adeh_0255; -.
DR   EnsemblBacteria; ABC80031; ABC80031; Adeh_0255.
DR   KEGG; ade:Adeh_0255; -.
DR   eggNOG; ENOG4108UEZ; Bacteria.
DR   eggNOG; COG0204; LUCA.
DR   HOGENOM; HOG000026379; -.
DR   KO; K00655; -.
DR   OMA; FKWVSKA; -.
DR   BioCyc; ADEH290397:G1G5W-261-MONOMER; -.
DR   Proteomes; UP000001935; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003841; F:1-acylglycerol-3-phosphate O-acyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR004552; AGP_acyltrans.
DR   InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR   Pfam; PF01553; Acyltransferase; 1.
DR   SMART; SM00563; PlsC; 1.
DR   TIGRFAMs; TIGR00530; AGP_acyltrn; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q2IMK2.
DR   SWISS-2DPAGE; Q2IMK2.
KW   Acyltransferase {ECO:0000256|RuleBase:RU361267,
KW   ECO:0000313|EMBL:ABC80031.1};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001935};
KW   Lipid biosynthesis {ECO:0000256|RuleBase:RU361267};
KW   Lipid metabolism {ECO:0000256|RuleBase:RU361267};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Phospholipid biosynthesis {ECO:0000256|RuleBase:RU361267};
KW   Phospholipid metabolism {ECO:0000256|RuleBase:RU361267};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001935};
KW   Transferase {ECO:0000256|RuleBase:RU361267,
KW   ECO:0000313|EMBL:ABC80031.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM      6     32       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     39     59       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     71     94       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       75    188       PlsC. {ECO:0000259|SMART:SM00563}.
SQ   SEQUENCE   244 AA;  27396 MW;  CA93FE016A8AE1A0 CRC64;
     MLAVFSFVYW IFFVLTLPFL FAVALVVFVL TAPFDPRRVA LQLWSCAWAS FYVVVNPLWR
     SRVVGREKLP WNGAAVLVAN HLSMLDILVL YGVFRPFKWV SKAELFRVPF VGWNMWLNDC
     VPVWRGDRES VRKMMAHCRA HLARGAPVMI FPEGTRSPDG RLQAFKDGAF RLAVDANVPV
     IPIAVSGTSE ALPKHGVVLR QRMRAEVRVL DPIHPSSFES PAALRDAVRE AIAAALPPEH
     RPGA
//

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