(data stored in ACNUC7421 zone)

SWISSPROT: Q145V5_PARXL

ID   Q145V5_PARXL            Unreviewed;       666 AA.
AC   Q145V5;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   08-MAY-2019, entry version 100.
DE   SubName: Full=Kef-type potassium/proton antiporter, CPA2 family {ECO:0000313|EMBL:ABE28884.1};
GN   ORFNames=Bxe_A4116 {ECO:0000313|EMBL:ABE28884.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE28884.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE28884.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE28884.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2
CC       (CPA2) transporter (TC 2.A.37) family.
CC       {ECO:0000256|SAAS:SAAS01092086}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000270; ABE28884.1; -; Genomic_DNA.
DR   RefSeq; WP_011486713.1; NZ_CP008760.1.
DR   STRING; 266265.Bxe_A4116; -.
DR   EnsemblBacteria; ABE28884; ABE28884; Bxe_A4116.
DR   GeneID; 4005036; -.
DR   KEGG; bxb:DR64_1792; -.
DR   KEGG; bxe:Bxe_A4116; -.
DR   PATRIC; fig|266265.5.peg.366; -.
DR   eggNOG; ENOG4105CKD; Bacteria.
DR   eggNOG; COG0475; LUCA.
DR   eggNOG; COG1226; LUCA.
DR   HOGENOM; HOG000179077; -.
DR   KO; K03455; -.
DR   OMA; DIRPFHD; -.
DR   OrthoDB; 941006at2; -.
DR   BioCyc; BXEN266265:BXE_RS01735-MONOMER; -.
DR   Proteomes; UP000001817; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015299; F:solute:proton antiporter activity; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   Gene3D; 1.20.1530.20; -; 1.
DR   Gene3D; 3.30.70.1450; -; 1.
DR   InterPro; IPR006153; Cation/H_exchanger.
DR   InterPro; IPR038770; Na+/solute_symporter_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   InterPro; IPR003148; RCK_N.
DR   Pfam; PF00999; Na_H_Exchanger; 1.
DR   Pfam; PF02080; TrkA_C; 1.
DR   Pfam; PF02254; TrkA_N; 1.
DR   SUPFAM; SSF116726; SSF116726; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS51202; RCK_C; 1.
DR   PROSITE; PS51201; RCK_N; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q145V5.
DR   SWISS-2DPAGE; Q145V5.
KW   Antiport {ECO:0000256|SAAS:SAAS01092098};
KW   Cell membrane {ECO:0000256|SAAS:SAAS00457490};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001817};
KW   Ion transport {ECO:0000256|SAAS:SAAS01092081};
KW   Membrane {ECO:0000256|SAAS:SAAS01092093, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001817};
KW   Transmembrane {ECO:0000256|SAAS:SAAS01092090,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS01092105,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|SAAS:SAAS01092095}.
FT   TRANSMEM      6     25       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     60     78       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     85    107       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    113    138       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    150    173       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    179    200       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    220    236       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    273    291       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    297    320       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    332    349       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    361    377       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      412    534       RCK N-terminal. {ECO:0000259|PROSITE:
FT                                PS51201}.
FT   DOMAIN      574    658       RCK C-terminal. {ECO:0000259|PROSITE:
FT                                PS51202}.
FT   COILED      642    666       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   666 AA;  71979 MW;  02AA4319CD82220E CRC64;
     MISPLEMTLF LLLASVAGVV TFRFLNLPPM LGYLTVGIVV GPHAFGLIPD SAGAQNLAEF
     GVVFLMFSIG LEFSLAKLRS MRRLVFGLGL LQVLGTIAVA VTLGFVLERW VHITWQASVA
     LGGALAMSST AIVSKMLAER LEIETEHGRN IFGVLLFQDL AVVPLLIVIA ALGGSSKDLV
     SSLGVAAIKI VVALSLLLIV GQRFMTRWFN VVARRRSQEL FILNLLLVTL GCAFITDKFG
     LSLALGAFIA GMLIAETPYR HQVEEDIKPF RDVLLGLFFI TTGMLLNPRV IWEHPLIVLG
     FLVGPILLKA VMITGLSRLF GASPGVAMRT GIGLAQAGEF GFVLLNLILD KHLVDATLLQ
     AILAAMLLSM LAAPFLIQNA DRIVLRLSST EWMMQSLQMT RIATQSLKQS GHVIICGYGR
     AGQNLARMLE HEGLSYVALD LDPDRVAAAA AAGESVVFGD AGRRESLLAA GIHRAAAIAI
     TYANTPSALR VLHNIHELEP TLPVIVRTVD DADLEKLLAA GATEVIPEIV EGSLMLASHT
     LVVMGVPMRR VVRRVEEMRD ERYALLRGYF HGADDVDDDD GHEQVRLQSV PVDENSDAVG
     RTLAELGLFE VGVEVTAIRR HGIRGVEPDP STKLRSSDIV VLRGLPEQLA EAEERLSKHR
     RAGAAA
//

If you have problems or comments...

PBIL Back to PBIL home page