(data stored in ACNUC7421 zone)

SWISSPROT: Q145U7_PARXL

ID   Q145U7_PARXL            Unreviewed;       385 AA.
AC   Q145U7;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   16-JAN-2019, entry version 62.
DE   SubName: Full=Major facilitator superfamily (MFS) multidrug efflux pump {ECO:0000313|EMBL:ABE28892.1};
GN   ORFNames=Bxe_A4107 {ECO:0000313|EMBL:ABE28892.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE28892.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE28892.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE28892.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
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DR   EMBL; CP000270; ABE28892.1; -; Genomic_DNA.
DR   RefSeq; WP_007179394.1; NZ_CP008760.1.
DR   STRING; 266265.Bxe_A4107; -.
DR   EnsemblBacteria; ABE28892; ABE28892; Bxe_A4107.
DR   GeneID; 4005045; -.
DR   KEGG; bxe:Bxe_A4107; -.
DR   eggNOG; ENOG4107RDB; Bacteria.
DR   eggNOG; COG0477; LUCA.
DR   HOGENOM; HOG000264695; -.
DR   OMA; YADSFHS; -.
DR   OrthoDB; 626204at2; -.
DR   BioCyc; BXEN266265:BXE_RS01780-MONOMER; -.
DR   Proteomes; UP000001817; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   4: Predicted;
DR   PRODOM; Q145U7.
DR   SWISS-2DPAGE; Q145U7.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001817};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001817};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     12     33       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     45     64       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     76     95       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    101    121       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    133    155       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    161    183       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    204    228       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    240    261       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    268    285       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    291    309       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    330    352       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    358    376       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN        8    383       MFS. {ECO:0000259|PROSITE:PS50850}.
SQ   SEQUENCE   385 AA;  40482 MW;  CE116BD7ECA28A7D CRC64;
     MSAPELRATV SLAAIFALRM LGLFMIMPVF SIYAKTIPGG DNVLLVGIAL GAYGVTQSML
     YIFYGWVSDK VGRKPVIATG LLIFALGSFV AAGAHDMTWI IVGRVIQGMG AVSSAVIAFI
     ADLTAEENRT KAMAMVGGSI GVSFAVAIVG APIVFQWVGM SGLFTLVGIF SILAVGVVLW
     IVPDAPKPVH VRAPFAEVLH NVELLRLNFG VLVLHATQTA LFLVVPRILE AGGLPVASHW
     KVYLPVMGLS FVMMVPAIIA AEKRGKMKIV LLSAIALILI GQLLLGVAPH TILSVAAILF
     VYFLGFNILE ASQPSLVSKL APGTRKGAAA GVYNTTQSIG LALGGVVGGW LLKADGQSAV
     FFTCSGLVFC WLIIAAKMKQ PPRKA
//

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