(data stored in ACNUC7421 zone)

SWISSPROT: UBIB_PARXL

ID   UBIB_PARXL              Reviewed;         525 AA.
AC   Q145N7;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   08-MAY-2019, entry version 88.
DE   RecName: Full=Probable protein kinase UbiB {ECO:0000255|HAMAP-Rule:MF_00414};
DE            EC=2.7.-.- {ECO:0000255|HAMAP-Rule:MF_00414};
DE   AltName: Full=Ubiquinone biosynthesis protein UbiB {ECO:0000255|HAMAP-Rule:MF_00414};
GN   Name=ubiB {ECO:0000255|HAMAP-Rule:MF_00414};
GN   OrderedLocusNames=Bxeno_A0414; ORFNames=Bxe_A4047;
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400;
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S.G., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- FUNCTION: Is probably a protein kinase regulator of UbiI activity
CC       which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00414}.
CC   -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis
CC       [regulation].
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00414}; Single-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00414}.
CC   -!- SIMILARITY: Belongs to the ABC1 family. UbiB subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_00414}.
DR   EMBL; CP000270; ABE28952.1; -; Genomic_DNA.
DR   RefSeq; WP_011486778.1; NZ_CP008760.1.
DR   SMR; Q145N7; -.
DR   STRING; 266265.Bxe_A4047; -.
DR   EnsemblBacteria; ABE28952; ABE28952; Bxe_A4047.
DR   GeneID; 4002222; -.
DR   KEGG; bxb:DR64_1724; -.
DR   KEGG; bxe:Bxe_A4047; -.
DR   PATRIC; fig|266265.5.peg.437; -.
DR   eggNOG; ENOG4105CNK; Bacteria.
DR   eggNOG; COG0661; LUCA.
DR   HOGENOM; HOG000264440; -.
DR   KO; K03688; -.
DR   OMA; DFGMMDQ; -.
DR   OrthoDB; 678616at2; -.
DR   BioCyc; BXEN266265:BXE_RS02075-MONOMER; -.
DR   UniPathway; UPA00232; -.
DR   Proteomes; UP000001817; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004672; F:protein kinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0010795; P:regulation of ubiquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd13972; UbiB; 1.
DR   HAMAP; MF_00414; UbiB; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR010232; UbiB.
DR   InterPro; IPR004147; UbiB_dom.
DR   Pfam; PF03109; ABC1; 1.
DR   SUPFAM; SSF56112; SSF56112; 1.
DR   TIGRFAMs; TIGR01982; UbiB; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q145N7.
DR   SWISS-2DPAGE; Q145N7.
KW   ATP-binding; Cell inner membrane; Cell membrane; Complete proteome;
KW   Kinase; Membrane; Nucleotide-binding; Reference proteome; Transferase;
KW   Transmembrane; Transmembrane helix; Ubiquinone biosynthesis.
FT   CHAIN         1    525       Probable protein kinase UbiB.
FT                                /FTId=PRO_1000123899.
FT   TRANSMEM    501    521       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_00414}.
FT   DOMAIN      118    500       Protein kinase. {ECO:0000255|HAMAP-
FT                                Rule:MF_00414}.
FT   NP_BIND     124    132       ATP. {ECO:0000255|HAMAP-Rule:MF_00414}.
FT   ACT_SITE    285    285       Proton acceptor. {ECO:0000255|HAMAP-
FT                                Rule:MF_00414}.
FT   BINDING     150    150       ATP. {ECO:0000255|HAMAP-Rule:MF_00414}.
SQ   SEQUENCE   525 AA;  59590 MW;  500A1023FF62A250 CRC64;
     MRFLRFLKIF FTVIRFGLDE MMLSRVNDRR VRLLLRITTI GRKFDAPPGV RLRLALESLG
     PIFVKFGQVL STRRDLLPVD IANELAKLQD QVPPFDSAVA IGLVEKSLGA PVDVLFDDFE
     RVPVASASIA QVHFATVKAG QHAGKAVAVK VLRPNMLPVI DSDLALLRDI AVWAERLWAD
     GKRLKPREVV AEFDKYLHDE LDLMREAANG SQLRRNFAGL DLLLVPEMYW EFCTPTVLVM
     ERMVGVPISQ VETLRAAGVD IPKLAREGVE IFFTQVFRDG FFHADMHPGN IQVSLDPAHF
     GRYIALDFGI IGALSDFDKN YLAQNFLAFF KRDYHRVATL HLESGWVPPT TRVEELESAI
     RAVCEPYFDR ALKDISLGQV LMRLFSTSRR FNVEIQPQLV LLQKTMLNVE GLGRSLDPEL
     DLWKTAKPYL ERWMNEQIGL RGWYERLKIE APQWSKTLPQ LPRLIHHALA ERHDHTRGAN
     DEMIRQILLE QKRTNRLLQG LLLFGVAVGV GAALARVFLA LAYGG
//

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