(data stored in ACNUC7421 zone)

SWISSPROT: Q145M2_PARXL

ID   Q145M2_PARXL            Unreviewed;      1036 AA.
AC   Q145M2;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   08-MAY-2019, entry version 81.
DE   SubName: Full=Putative diguanylate cyclase/phosphodiesterase(GGDEF & EAL domains) with PAS/PAC sensor(S) {ECO:0000313|EMBL:ABE28967.1};
GN   ORFNames=Bxe_A4032 {ECO:0000313|EMBL:ABE28967.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE28967.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE28967.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE28967.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000270; ABE28967.1; -; Genomic_DNA.
DR   RefSeq; WP_011486793.1; NZ_CP008760.1.
DR   STRING; 266265.Bxe_A4032; -.
DR   EnsemblBacteria; ABE28967; ABE28967; Bxe_A4032.
DR   GeneID; 4004330; -.
DR   KEGG; bxb:DR64_1709; -.
DR   KEGG; bxe:Bxe_A4032; -.
DR   PATRIC; fig|266265.5.peg.452; -.
DR   eggNOG; ENOG4105BZU; Bacteria.
DR   eggNOG; ENOG410XNMH; LUCA.
DR   HOGENOM; HOG000136246; -.
DR   OMA; ERACDEM; -.
DR   OrthoDB; 1635706at2; -.
DR   BioCyc; BXEN266265:BXE_RS02150-MONOMER; -.
DR   Proteomes; UP000001817; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 2.
DR   Gene3D; 3.20.20.450; -; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   Pfam; PF13188; PAS_8; 1.
DR   Pfam; PF13426; PAS_9; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00086; PAC; 3.
DR   SMART; SM00091; PAS; 3.
DR   SUPFAM; SSF141868; SSF141868; 1.
DR   SUPFAM; SSF55073; SSF55073; 1.
DR   SUPFAM; SSF55785; SSF55785; 3.
DR   TIGRFAMs; TIGR00254; GGDEF; 1.
DR   TIGRFAMs; TIGR00229; sensory_box; 3.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 2.
DR   PROSITE; PS50112; PAS; 2.
PE   4: Predicted;
DR   PRODOM; Q145M2.
DR   SWISS-2DPAGE; Q145M2.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001817};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001817};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     29       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        30   1036       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5004182904.
FT   TRANSMEM    184    205       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      223    268       PAS. {ECO:0000259|PROSITE:PS50112}.
FT   DOMAIN      423    476       PAC. {ECO:0000259|PROSITE:PS50113}.
FT   DOMAIN      473    546       PAS. {ECO:0000259|PROSITE:PS50112}.
FT   DOMAIN      547    601       PAC. {ECO:0000259|PROSITE:PS50113}.
FT   DOMAIN      633    766       GGDEF. {ECO:0000259|PROSITE:PS50887}.
FT   DOMAIN      775   1029       EAL. {ECO:0000259|PROSITE:PS50883}.
SQ   SEQUENCE   1036 AA;  114329 MW;  590359BC5CECE276 CRC64;
     MTPFLSKRLL INLAVVAAAV GANAFVAYAQ ICGQRDADAR MLRSTSVRQN LDAYQSALDG
     GLAALGRFET SGESAPAGAA TSMAATLTRL ESDLRGELAG DPAMLDALAR LSADSHALQH
     DIDDALLRSA DSGASASRPW AASTYTHLGL GMHRVEAALA ALRGEENRAL RASLAASASE
     TQRAMFLLIV TMLAGSVLLI YTFGARESSA REKLRTVRAL GRNDERFRGL FDDHPVPMYI
     VDRETLRFLA VNAAAIQQYG YSESEFLGMT IRAIRPKAEI SRLESHLQRS DATHHGRTMA
     GIWHHRRKDG STISADISYH ALNFMGRAAF FVLADDVTDQ INAEAEAQRS NQMLEAVIDN
     IPQRIFWKDL ESRYLGCNMA FARDAGLAYP EQVVGKSDAD MPWRDFSSLL NDHDREVAST
     GVPKMNFEVD LMIDGVHRTT VTSKLPFTDG DGRVIGVLGS YTDITERKRA DLALRLQSRA
     LDASVNAILI TAPSPAGNLI EYVNPAFMRI TGYDAAEAIG HDCRLLQRDD RDQEGVALIR
     QALAANREVS AVVRNYRKDG ALFWNQLFIA PVPDQDGVIT HHIGVINDVT DLMRYQEQLE
     YQANYDSLTR LPNRNLLRDR LQHALIVAQR HHKGVAVVFI DLDGFKNVND SLGHSVGDRL
     LSVVAERLAR CTRTSDTVAR HGGDEFVIVM TDTVDEKSLI AWMERVRVSI SEPVWLDGTE
     LYVGCSMGAS LFPQDGEDAE TLMKKADLAM YRAKDMGRNT FQFYQPEMNA SAGTRLNLER
     RLRRALRDNQ FLLHYQPQVD IVSGQIVGTE ALVRWRDPEV GLVPPSSFIP VAEESGLIGP
     LSEWVLREAC RQNKAWQDEG LPPARVSVNL SARVFQQRDI AKLVMQVLDE TGLEPQYLEL
     ELTESTIMRN AEEAVSMLNE LHALGIGLAI DDFGTGYSSL SYLKRFPVDR LKIDRSFVSD
     IGISGDDETI TSAIIALAHS LKLQVIAEGV ETSAQLDFLK ERACDEMQGF YFAKPLSTDA
     ISELLQGGVG RELATV
//

If you have problems or comments...

PBIL Back to PBIL home page