(data stored in SCRATCH zone)

SWISSPROT: Q13S77_PARXL

ID   Q13S77_PARXL            Unreviewed;       365 AA.
AC   Q13S77;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   08-MAY-2019, entry version 106.
DE   RecName: Full=Spermidine/putrescine import ATP-binding protein PotA {ECO:0000256|RuleBase:RU364083};
DE            EC=7.6.2.11 {ECO:0000256|RuleBase:RU364083};
GN   Name=potA {ECO:0000256|RuleBase:RU364083};
GN   ORFNames=Bxe_B2933 {ECO:0000313|EMBL:ABE33062.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE33062.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE33062.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE33062.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- FUNCTION: Part of the ABC transporter complex PotABCD involved in
CC       spermidine/putrescine import. Responsible for energy coupling to
CC       the transport system. {ECO:0000256|RuleBase:RU364083,
CC       ECO:0000256|SAAS:SAAS00083152}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H(2)O + polyamine-[polyamine-binding protein](Side
CC         1) = ADP + phosphate + polyamine(Side 2) + [polyamine-binding
CC         protein](Side 1).; EC=7.6.2.11;
CC         Evidence={ECO:0000256|RuleBase:RU364083,
CC         ECO:0000256|SAAS:SAAS01153263};
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins
CC       (PotA), two transmembrane proteins (PotB and PotC) and a solute-
CC       binding protein (PotD). {ECO:0000256|RuleBase:RU364083,
CC       ECO:0000256|SAAS:SAAS00083151}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily.
CC       Spermidine/putrescine importer (TC 3.A.1.11.1) family.
CC       {ECO:0000256|RuleBase:RU364083, ECO:0000256|SAAS:SAAS00569590}.
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DR   EMBL; CP000271; ABE33062.1; -; Genomic_DNA.
DR   RefSeq; WP_011490450.1; NZ_CP008762.1.
DR   STRING; 266265.Bxe_B2933; -.
DR   EnsemblBacteria; ABE33062; ABE33062; Bxe_B2933.
DR   GeneID; 4006819; -.
DR   KEGG; bxb:DR64_5264; -.
DR   KEGG; bxe:Bxe_B2933; -.
DR   PATRIC; fig|266265.5.peg.4754; -.
DR   eggNOG; ENOG4105C53; Bacteria.
DR   eggNOG; COG3842; LUCA.
DR   KO; K02052; -.
DR   OMA; RIAIFSH; -.
DR   OrthoDB; 1200451at2; -.
DR   BioCyc; BXEN266265:BXE_RS22540-MONOMER; -.
DR   Proteomes; UP000001817; Chromosome 2.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0015417; F:polyamine-transporting ATPase activity; IEA:InterPro.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like.
DR   InterPro; IPR017871; ABC_transporter_CS.
DR   InterPro; IPR008995; Mo/tungstate-bd_C_term_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005893; Sp_pt_ABC_ATP-bd.
DR   InterPro; IPR013611; Transp-assoc_OB_typ2.
DR   Pfam; PF00005; ABC_tran; 1.
DR   Pfam; PF08402; TOBE_2; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF50331; SSF50331; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01187; potA; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q13S77.
DR   SWISS-2DPAGE; Q13S77.
KW   ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00434,
KW   ECO:0000256|RuleBase:RU364083, ECO:0000256|SAAS:SAAS00237035};
KW   Cell membrane {ECO:0000256|RuleBase:RU364083,
KW   ECO:0000256|SAAS:SAAS00458580};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001817};
KW   Membrane {ECO:0000256|RuleBase:RU364083,
KW   ECO:0000256|SAAS:SAAS00458555};
KW   Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00434,
KW   ECO:0000256|RuleBase:RU364083, ECO:0000256|SAAS:SAAS00452314};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001817};
KW   Translocase {ECO:0000256|RuleBase:RU364083,
KW   ECO:0000256|SAAS:SAAS01153264};
KW   Transport {ECO:0000256|RuleBase:RU364083,
KW   ECO:0000256|SAAS:SAAS00237071}.
FT   DOMAIN        1    239       ABC transporter. {ECO:0000259|PROSITE:
FT                                PS50893}.
FT   NP_BIND      41     48       ATP. {ECO:0000256|PROSITE-ProRule:
FT                                PRU00434}.
SQ   SEQUENCE   365 AA;  40308 MW;  996F5B069FCBE03B CRC64;
     MKTDDVIVSF RGVRKTYDGE TLVVKQLDLD IYQGEFLTLL GPSGSGKTTC LMMLAGFEFP
     TGGEIWLDGT LLNTVPPHKR NIGMVFQNYA LFPHLTVEQN VAYPLTVRKI SAQERAHRTN
     NALKMVRMES FAKRYPAQLS GGQQQRIALA RALVFEPKLV LMDEPLGALD KQLREHMQYE
     LKSLHEKLGV TFVYVTHDQG EALTMSDRVA VFDKGIVQQL DTVDRLYESP CNEFVANFIG
     DSNRLRGTIA NVDGEYCEFR LSDGTRLTGR NIGGARAGTP AVACIRPERM KLANGLSRPG
     ANALAGEARG LIYFGDHVRM RCGLPQQDEC FVKVPLGTDA LDTFAPGAPV ALEFAPEHLR
     VFAGA
//

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