(data stored in SCRATCH zone)

SWISSPROT: Q13GN0_PARXL

ID   Q13GN0_PARXL            Unreviewed;       298 AA.
AC   Q13GN0;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   08-MAY-2019, entry version 82.
DE   SubName: Full=Heavy metal efflux pump, CDF family {ECO:0000313|EMBL:ABE31828.1};
DE   SubName: Full=Heavy metal/H+ antiporter, CDF family {ECO:0000313|EMBL:ABE36759.1};
GN   ORFNames=Bxe_A1104 {ECO:0000313|EMBL:ABE31842.1}, Bxe_A1118
GN   {ECO:0000313|EMBL:ABE31828.1}, Bxe_A2903
GN   {ECO:0000313|EMBL:ABE30073.1}, Bxe_B1605
GN   {ECO:0000313|EMBL:ABE34359.1}, Bxe_B2911
GN   {ECO:0000313|EMBL:ABE33084.1}, Bxe_C0391
GN   {ECO:0000313|EMBL:ABE36298.1}, Bxe_C0883
GN   {ECO:0000313|EMBL:ABE36759.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE36759.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE36759.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE36759.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
RN   [2] {ECO:0000313|EMBL:ABE30073.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE30073.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P.,
RA   Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Lykidis A., Richardson P.;
RT   "Complete sequence of Chromosome 1 of Burkholderia xenovorans LB400.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:ABE33084.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE33084.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P.,
RA   Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Lykidis A., Richardson P.;
RT   "Complete sequence of Chromosome 2 of Burkholderia xenovorans LB400.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|EMBL:ABE36759.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE36759.1};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Chain P.,
RA   Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA   Kyrpides N., Lykidis A., Richardson P.;
RT   "Complete sequence of Chromosome 3 of Burkholderia xenovorans LB400.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00280}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000270; ABE30073.1; -; Genomic_DNA.
DR   EMBL; CP000270; ABE31828.1; -; Genomic_DNA.
DR   EMBL; CP000270; ABE31842.1; -; Genomic_DNA.
DR   EMBL; CP000271; ABE33084.1; -; Genomic_DNA.
DR   EMBL; CP000271; ABE34359.1; -; Genomic_DNA.
DR   EMBL; CP000272; ABE36298.1; -; Genomic_DNA.
DR   EMBL; CP000272; ABE36759.1; -; Genomic_DNA.
DR   RefSeq; WP_004574643.1; NZ_CP008762.1.
DR   STRING; 266265.Bxe_C0883; -.
DR   EnsemblBacteria; ABE30073; ABE30073; Bxe_A2903.
DR   EnsemblBacteria; ABE31828; ABE31828; Bxe_A1118.
DR   EnsemblBacteria; ABE31842; ABE31842; Bxe_A1104.
DR   EnsemblBacteria; ABE33084; ABE33084; Bxe_B2911.
DR   EnsemblBacteria; ABE34359; ABE34359; Bxe_B1605.
DR   EnsemblBacteria; ABE36298; ABE36298; Bxe_C0391.
DR   EnsemblBacteria; ABE36759; ABE36759; Bxe_C0883.
DR   GeneID; 4010396; -.
DR   KEGG; bxb:DR64_3268; -.
DR   KEGG; bxb:DR64_3282; -.
DR   KEGG; bxb:DR64_585; -.
DR   KEGG; bxb:DR64_6908; -.
DR   KEGG; bxb:DR64_7566; -.
DR   KEGG; bxb:DR64_8051; -.
DR   KEGG; bxb:DR64_853; -.
DR   KEGG; bxe:Bxe_A1104; -.
DR   KEGG; bxe:Bxe_A1118; -.
DR   KEGG; bxe:Bxe_A2903; -.
DR   KEGG; bxe:Bxe_B1605; -.
DR   KEGG; bxe:Bxe_B2911; -.
DR   KEGG; bxe:Bxe_C0391; -.
DR   KEGG; bxe:Bxe_C0883; -.
DR   eggNOG; ENOG4105D04; Bacteria.
DR   eggNOG; COG1230; LUCA.
DR   HOGENOM; HOG000002625; -.
DR   OMA; EPESLMM; -.
DR   OrthoDB; 948593at2; -.
DR   BioCyc; BXEN266265:BXE_RS07610-MONOMER; -.
DR   BioCyc; BXEN266265:BXE_RS16365-MONOMER; -.
DR   BioCyc; BXEN266265:BXE_RS16430-MONOMER; -.
DR   BioCyc; BXEN266265:BXE_RS22645-MONOMER; -.
DR   BioCyc; BXEN266265:BXE_RS29080-MONOMER; -.
DR   BioCyc; BXEN266265:BXE_RS38535-MONOMER; -.
DR   BioCyc; BXEN266265:BXE_RS40855-MONOMER; -.
DR   Proteomes; UP000001817; Chromosome 3.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0030001; P:metal ion transport; IEA:InterPro.
DR   CDD; cd00371; HMA; 1.
DR   Gene3D; 1.20.1510.10; -; 1.
DR   InterPro; IPR002524; Cation_efflux.
DR   InterPro; IPR027469; Cation_efflux_TMD_sf.
DR   InterPro; IPR006121; HMA_dom.
DR   InterPro; IPR036163; HMA_dom_sf.
DR   Pfam; PF01545; Cation_efflux; 1.
DR   SUPFAM; SSF161111; SSF161111; 1.
DR   SUPFAM; SSF55008; SSF55008; 1.
DR   PROSITE; PS50846; HMA_2; 1.
PE   4: Predicted;
DR   PRODOM; Q13GN0.
DR   SWISS-2DPAGE; Q13GN0.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001817};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001817};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    125    144       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    156    174       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    181    200       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    212    232       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    253    270       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    276    294       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       32     95       HMA. {ECO:0000259|PROSITE:PS50846}.
SQ   SEQUENCE   298 AA;  31194 MW;  42FC9444CDF07538 CRC64;
     MSKSCGGACG GDATSAADTD IQASSEAPGR WVSVYAVPKM DCPSEERMIR LALNGFEEIR
     ALSFDLSNRR LKVVHDGEVE PVTSKLKTLG LGASLQETVA ANPETIKAAE FSAASAKQES
     GTLRWLLGIN ALLFVVEMTA GLIAQSTGLI GESLDNFADA AVYGLALYAV GHSVKMQVRA
     AHLAGVLQLI LAVGVLVEVV RRFVFGSEPE SLVMMAIAFV ALIANTSCLL LISKHREGGA
     HMKASWIFSA NDVVINLGVI TAGALVAWTG SNYPDLIIGT IAGGIVLNGA RRILALKG
//

If you have problems or comments...

PBIL Back to PBIL home page