(data stored in ACNUC7421 zone)

SWISSPROT: Q13S37_PARXL

ID   Q13S37_PARXL            Unreviewed;       591 AA.
AC   Q13S37;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   07-JUN-2017, entry version 74.
DE   RecName: Full=Succinate dehydrogenase flavoprotein subunit {ECO:0000256|RuleBase:RU362051};
DE            EC=1.3.5.1 {ECO:0000256|RuleBase:RU362051};
GN   ORFNames=Bxe_B2893 {ECO:0000313|EMBL:ABE33102.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE33102.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE33102.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE33102.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S.G., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- CATALYTIC ACTIVITY: Succinate + a quinone = fumarate + a quinol.
CC       {ECO:0000256|RuleBase:RU362051}.
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000256|RuleBase:RU362051};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       fumarate from succinate (bacterial route): step 1/1.
CC       {ECO:0000256|RuleBase:RU362051}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|RuleBase:RU362051}; Peripheral membrane protein
CC       {ECO:0000256|RuleBase:RU362051}; Cytoplasmic side
CC       {ECO:0000256|RuleBase:RU362051}.
CC   -!- SIMILARITY: Belongs to the FAD-dependent oxidoreductase 2 family.
CC       FRD/SDH subfamily. {ECO:0000256|RuleBase:RU362051}.
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DR   EMBL; CP000271; ABE33102.1; -; Genomic_DNA.
DR   RefSeq; WP_011490485.1; NZ_CP008762.1.
DR   ProteinModelPortal; Q13S37; -.
DR   STRING; 266265.Bxe_B2893; -.
DR   EnsemblBacteria; ABE33102; ABE33102; Bxe_B2893.
DR   GeneID; 4006742; -.
DR   KEGG; bxb:DR64_5223; -.
DR   KEGG; bxe:Bxe_B2893; -.
DR   PATRIC; fig|266265.5.peg.4794; -.
DR   eggNOG; ENOG4105C00; Bacteria.
DR   eggNOG; COG1053; LUCA.
DR   HOGENOM; HOG000160475; -.
DR   KO; K00239; -.
DR   OMA; GDSPWEH; -.
DR   OrthoDB; POG091H02TE; -.
DR   UniPathway; UPA00223; UER01005.
DR   Proteomes; UP000001817; Chromosome 2.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0008177; F:succinate dehydrogenase (ubiquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0022900; P:electron transport chain; IEA:InterPro.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway.
DR   Gene3D; 1.20.58.100; -; 1.
DR   Gene3D; 3.50.50.60; -; 2.
DR   InterPro; IPR003953; FAD-binding_2.
DR   InterPro; IPR023753; FAD/NAD-binding_dom.
DR   InterPro; IPR003952; FRD_SDH_FAD_BS.
DR   InterPro; IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
DR   InterPro; IPR027477; Succ_DH/fumarate_Rdtase_cat.
DR   InterPro; IPR011281; Succ_DH_flav_su_fwd.
DR   InterPro; IPR014006; Succ_Dhase_FrdA_Gneg.
DR   Pfam; PF00890; FAD_binding_2; 1.
DR   Pfam; PF02910; Succ_DH_flav_C; 1.
DR   SUPFAM; SSF46977; SSF46977; 1.
DR   SUPFAM; SSF51905; SSF51905; 2.
DR   SUPFAM; SSF56425; SSF56425; 1.
DR   TIGRFAMs; TIGR01816; sdhA_forward; 1.
DR   TIGRFAMs; TIGR01812; sdhA_frdA_Gneg; 1.
DR   PROSITE; PS00504; FRD_SDH_FAD_BINDING; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q13S37.
DR   SWISS-2DPAGE; Q13S37.
KW   Cell inner membrane {ECO:0000256|RuleBase:RU362051};
KW   Cell membrane {ECO:0000256|RuleBase:RU362051};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001817};
KW   Electron transport {ECO:0000256|RuleBase:RU362051};
KW   FAD {ECO:0000256|RuleBase:RU362051};
KW   Flavoprotein {ECO:0000256|RuleBase:RU362051};
KW   Membrane {ECO:0000256|RuleBase:RU362051};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU362051,
KW   ECO:0000313|EMBL:ABE33102.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001817};
KW   Transport {ECO:0000256|RuleBase:RU362051};
KW   Tricarboxylic acid cycle {ECO:0000256|RuleBase:RU362051}.
FT   DOMAIN       14    408       FAD_binding_2. {ECO:0000259|Pfam:
FT                                PF00890}.
FT   DOMAIN      465    590       Succ_DH_flav_C. {ECO:0000259|Pfam:
FT                                PF02910}.
SQ   SEQUENCE   591 AA;  64419 MW;  3F81BF64C40D5760 CRC64;
     MAAIKNSLPR RKFDVVIVGA GGSGMRASLQ LARAGLSVCV LSKVFPTRSH TVAAQGGIGA
     SLGNMSEDNW HYHFYDTIKG SDWLGDQDAI EYMCREAPNA VYELEHFGMP FDRNADGTIY
     QRPFGGHTAN YGEKPVQRAC AAADRTGHAL LHTLYQQNVA AKTQFFVEWM ALDLIRDAEG
     DVLGVTALEM ETGDVYILEG KTTLFATGGA GRIFAASTNA FINTGDGLGM AARSGIALQD
     MEFWQFHPTG VAGAGVLITE GVRGEGGILR NSNGERFMER YAPTLKDLAP RDFVSRSMDQ
     EIKEGRGVGP NKDHVLLDLS HIGAETIMKR LPSIREIALK FANVDCIKEP IPVVPTIHYQ
     MGGIPTNIHG QVVGTSKGAE DPVNGFYAVG ECSCVSVHGA NRLGTNSLLD LVVFGRAAGN
     HIVKHVKEIK EHKPLPADAA DFALSRLAKL DSSSSGEYAQ SVANDIRGTM QKHAGVFRTS
     ALLAEGVERI REVADRVDNI HLKDKSKVFN TARIEALEVA NLIEVARATM VSAEARKESR
     GAHAQDDFEH RDDENWLRHT LWFSKGDRLD YKPVHMQPLT VESVPPKART F
//

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