(data stored in SCRATCH zone)

SWISSPROT: Q13S21_PARXL

ID   Q13S21_PARXL            Unreviewed;       436 AA.
AC   Q13S21;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   16-JAN-2019, entry version 81.
DE   SubName: Full=Folylpolyglutamate synthetase {ECO:0000313|EMBL:ABE33118.1};
DE            EC=6.3.2.17 {ECO:0000313|EMBL:ABE33118.1};
GN   ORFNames=Bxe_B2877 {ECO:0000313|EMBL:ABE33118.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE33118.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE33118.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE33118.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- SIMILARITY: Belongs to the folylpolyglutamate synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001563}.
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DR   EMBL; CP000271; ABE33118.1; -; Genomic_DNA.
DR   RefSeq; WP_011490501.1; NZ_CP008762.1.
DR   STRING; 266265.Bxe_B2877; -.
DR   EnsemblBacteria; ABE33118; ABE33118; Bxe_B2877.
DR   GeneID; 4006758; -.
DR   KEGG; bxb:DR64_5207; -.
DR   KEGG; bxe:Bxe_B2877; -.
DR   PATRIC; fig|266265.5.peg.4812; -.
DR   eggNOG; ENOG4105DPM; Bacteria.
DR   eggNOG; COG0285; LUCA.
DR   HOGENOM; HOG000019982; -.
DR   KO; K11754; -.
DR   OMA; YFEMGTL; -.
DR   OrthoDB; 1232874at2; -.
DR   BioCyc; BXEN266265:BXE_RS22810-MONOMER; -.
DR   Proteomes; UP000001817; Chromosome 2.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004326; F:tetrahydrofolylpolyglutamate synthase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.1190.10; -; 1.
DR   Gene3D; 3.90.190.20; -; 1.
DR   InterPro; IPR001645; Folylpolyglutamate_synth.
DR   InterPro; IPR018109; Folylpolyglutamate_synth_CS.
DR   InterPro; IPR036565; Mur-like_cat_sf.
DR   InterPro; IPR036615; Mur_ligase_C_dom_sf.
DR   InterPro; IPR013221; Mur_ligase_cen.
DR   PANTHER; PTHR11136; PTHR11136; 1.
DR   Pfam; PF08245; Mur_ligase_M; 1.
DR   PIRSF; PIRSF001563; Folylpolyglu_synth; 1.
DR   SUPFAM; SSF53244; SSF53244; 1.
DR   SUPFAM; SSF53623; SSF53623; 1.
DR   TIGRFAMs; TIGR01499; folC; 1.
DR   PROSITE; PS01011; FOLYLPOLYGLU_SYNT_1; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q13S21.
DR   SWISS-2DPAGE; Q13S21.
KW   ATP-binding {ECO:0000256|PIRNR:PIRNR001563};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001817};
KW   Ligase {ECO:0000256|PIRNR:PIRNR001563, ECO:0000313|EMBL:ABE33118.1};
KW   Nucleotide-binding {ECO:0000256|PIRNR:PIRNR001563};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001817}.
FT   DOMAIN       47    268       Mur_ligase_M. {ECO:0000259|Pfam:PF08245}.
SQ   SEQUENCE   436 AA;  47138 MW;  963412E544E66DCB CRC64;
     MTTFPTLDAW LTHLESAHPV GIDMGLARIA QVRDAMQLSF ACPVITVGGT NGKGSTCAIL
     ESILLRAGYT VGCHTSPHLL SFNERARVNG EMASDADLLP HFEAVEAARL SLAEPVTLTY
     FEFTTLAIMS LFASRGLDAV IFEVGLGGRL DAVNILDTDC AIITSIDIDH TDYLGDTREK
     IAFEKAGIFR PGKPAICADP VPPQSLIDYA EKIGAQLWLF GRDFRYEGQA GSERQQWSYV
     GPTMRRSALA YPALRGANQL INTSAALAGL EALRDRLPVS AQDIRLGLAN VELPGRFQVL
     PGKPAIVLDV GHNPHAAAVL TQNLGNMGFF PYTYAVFGAM RDKDIAGLLT HLKGEIDHWC
     VTDLPTPRAA SAEQLEAALR EQGVGESADS SVTRYATPAE AFQDALKRAS ENDRIVVFGS
     FYTVAGVMAY RKSQQH
//

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