(data stored in SCRATCH zone)

SWISSPROT: Q13RR7_PARXL

ID   Q13RR7_PARXL            Unreviewed;       377 AA.
AC   Q13RR7;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   08-MAY-2019, entry version 77.
DE   SubName: Full=4-hydroxyphenylpyruvate dioxygenase {ECO:0000313|EMBL:ABE33222.1};
DE            EC=1.13.11.27 {ECO:0000313|EMBL:ABE33222.1};
GN   ORFNames=Bxe_B2773 {ECO:0000313|EMBL:ABE33222.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE33222.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE33222.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE33222.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- COFACTOR:
CC       Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC         Evidence={ECO:0000256|PIRSR:PIRSR009283-1};
CC       Note=Binds 1 Fe cation per subunit.
CC       {ECO:0000256|PIRSR:PIRSR009283-1};
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DR   EMBL; CP000271; ABE33222.1; -; Genomic_DNA.
DR   RefSeq; WP_011490594.1; NZ_CP008762.1.
DR   STRING; 266265.Bxe_B2773; -.
DR   EnsemblBacteria; ABE33222; ABE33222; Bxe_B2773.
DR   GeneID; 4006511; -.
DR   KEGG; bxb:DR64_5106; -.
DR   KEGG; bxe:Bxe_B2773; -.
DR   PATRIC; fig|266265.5.peg.4917; -.
DR   eggNOG; ENOG4106K5S; Bacteria.
DR   eggNOG; COG3185; LUCA.
DR   HOGENOM; HOG000188688; -.
DR   KO; K00457; -.
DR   OMA; TELMHAY; -.
DR   OrthoDB; 402639at2; -.
DR   BioCyc; BXEN266265:BXE_RS23325-MONOMER; -.
DR   Proteomes; UP000001817; Chromosome 2.
DR   GO; GO:0003868; F:4-hydroxyphenylpyruvate dioxygenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0009072; P:aromatic amino acid family metabolic process; IEA:InterPro.
DR   CDD; cd07250; HPPD_C_like; 1.
DR   CDD; cd08342; HPPD_N_like; 1.
DR   Gene3D; 3.10.180.10; -; 2.
DR   InterPro; IPR005956; 4OHPhenylPyrv_dOase.
DR   InterPro; IPR041735; 4OHPhenylPyrv_dOase_C.
DR   InterPro; IPR041736; 4OHPhenylPyrv_dOase_N.
DR   InterPro; IPR029068; Glyas_Bleomycin-R_OHBP_Dase.
DR   InterPro; IPR004360; Glyas_Fos-R_dOase_dom.
DR   InterPro; IPR037523; VOC.
DR   PANTHER; PTHR11959; PTHR11959; 1.
DR   Pfam; PF00903; Glyoxalase; 1.
DR   PIRSF; PIRSF009283; HPP_dOase; 1.
DR   SUPFAM; SSF54593; SSF54593; 1.
DR   PROSITE; PS51819; VOC; 2.
PE   4: Predicted;
DR   PRODOM; Q13RR7.
DR   SWISS-2DPAGE; Q13RR7.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001817};
KW   Dioxygenase {ECO:0000313|EMBL:ABE33222.1};
KW   Iron {ECO:0000256|PIRSR:PIRSR009283-1};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR009283-1};
KW   Oxidoreductase {ECO:0000313|EMBL:ABE33222.1};
KW   Pyruvate {ECO:0000313|EMBL:ABE33222.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001817}.
FT   DOMAIN       27    145       VOC. {ECO:0000259|PROSITE:PS51819}.
FT   DOMAIN      187    338       VOC. {ECO:0000259|PROSITE:PS51819}.
FT   METAL       190    190       Iron. {ECO:0000256|PIRSR:PIRSR009283-1}.
FT   METAL       268    268       Iron. {ECO:0000256|PIRSR:PIRSR009283-1}.
FT   METAL       350    350       Iron. {ECO:0000256|PIRSR:PIRSR009283-1}.
SQ   SEQUENCE   377 AA;  41633 MW;  DF76CDAF413BED63 CRC64;
     MPSDLPTPDA ALRAVSAPEH NPLGTAGLEF VEFAARDPRA LGETFTKLGF KAIARHISKD
     VTLYRQGEMQ FLINAEPDSF AARYAEEYGA GICAIGIRVA DAQRAFGRAI ELGAWAFEGE
     KIGAGELLIP AIQGIGDSHI YFVDRWRGRG GQRGGLGDIS IFDIDFRPIQ IDTAQADLSH
     VGTGLVAVDH LTQTVGEGRM QEWLDFYRDL LNFREIHELH ANWHVSAESR VMVSPCGAIR
     VPLYEEGTRR TNLMHEYLPD HPGEGVQHIA LATDDIFACV EQLLANGVEF VEPPARYYEQ
     LDARLPGHGL DVERLRRTHL LVDGEIGTDG VPLLFFQTFV RRRAGEIFFE IVQRQGHHGF
     GEGNLSALAQ AREQAGA
//

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