(data stored in SCRATCH zone)

SWISSPROT: Q13RP4_PARXL

ID   Q13RP4_PARXL            Unreviewed;       349 AA.
AC   Q13RP4;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   08-MAY-2019, entry version 87.
DE   SubName: Full=4-hydroxythreonine-4-phosphate dehydrogenase {ECO:0000313|EMBL:ABE33245.1};
DE            EC=1.1.1.262 {ECO:0000313|EMBL:ABE33245.1};
GN   ORFNames=Bxe_B2750 {ECO:0000313|EMBL:ABE33245.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE33245.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE33245.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE33245.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
RN   [2] {ECO:0000213|PDB:4ATY}
RP   X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS) IN COMPLEX WITH ZINC.
RX   PubMed=22889862; DOI=10.1016/j.jmb.2012.07.022;
RA   Bains J., Wulff J.E., Boulanger M.J.;
RT   "Investigating terephthalate biodegradation: structural
RT   characterization of a putative decarboxylating cis-dihydrodiol
RT   dehydrogenase.";
RL   J. Mol. Biol. 423:284-293(2012).
CC   -!- SIMILARITY: Belongs to the PdxA family.
CC       {ECO:0000256|SAAS:SAAS00701249}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000271; ABE33245.1; -; Genomic_DNA.
DR   RefSeq; WP_011490615.1; NZ_CP008762.1.
DR   PDB; 4ATY; X-ray; 1.85 A; A=1-349.
DR   PDBsum; 4ATY; -.
DR   SMR; Q13RP4; -.
DR   STRING; 266265.Bxe_B2750; -.
DR   EnsemblBacteria; ABE33245; ABE33245; Bxe_B2750.
DR   GeneID; 4006534; -.
DR   KEGG; bxb:DR64_5083; -.
DR   KEGG; bxe:Bxe_B2750; -.
DR   PATRIC; fig|266265.5.peg.4944; -.
DR   eggNOG; ENOG4108U57; Bacteria.
DR   eggNOG; COG1995; LUCA.
DR   HOGENOM; HOG000221593; -.
DR   KO; K00097; -.
DR   OMA; YERPRIA; -.
DR   OrthoDB; 1414545at2; -.
DR   BioCyc; BXEN266265:BXE_RS23440-MONOMER; -.
DR   Proteomes; UP000001817; Chromosome 2.
DR   GO; GO:0050570; F:4-hydroxythreonine-4-phosphate dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   InterPro; IPR005255; PdxA_fam.
DR   PANTHER; PTHR30004; PTHR30004; 1.
DR   Pfam; PF04166; PdxA; 1.
PE   1: Evidence at protein level;
DR   PRODOM; Q13RP4.
DR   SWISS-2DPAGE; Q13RP4.
KW   3D-structure {ECO:0000213|PDB:4ATY};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001817};
KW   Metal-binding {ECO:0000213|PDB:4ATY, ECO:0000256|SAAS:SAAS00701256};
KW   NAD {ECO:0000256|SAAS:SAAS00701266};
KW   Oxidoreductase {ECO:0000256|SAAS:SAAS00701261,
KW   ECO:0000313|EMBL:ABE33245.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001817};
KW   Zinc {ECO:0000213|PDB:4ATY}.
FT   METAL       187    187       Zinc; via tele nitrogen.
FT                                {ECO:0000213|PDB:4ATY}.
FT   METAL       231    231       Zinc; via tele nitrogen.
FT                                {ECO:0000213|PDB:4ATY}.
FT   METAL       283    283       Zinc; via tele nitrogen.
FT                                {ECO:0000213|PDB:4ATY}.
SQ   SEQUENCE   349 AA;  36305 MW;  5990100E0CF6D906 CRC64;
     MSRTRDRAMT VALAIGDPNG IGPEIAVKAA AQMARDERSE HGGHAVHSQP RIVLFGDAFV
     IRRYARQCCP ELMLRLVQLD DLPSAEPNAI DMVDVASLPA EAFVPGEVAA AAGTATLAYV
     SAALRAARAG QVDAVIACPH SETAINASGV RFAGYPGFVA HEMGMPAEDV YLLLIGGGLR
     IVHATLHEGI ASALARLDQR HVERAARAAV QALQLMGIAH PVVGLMGINP HAGEGGLFGR
     DDIDITEPVA RKLRDDGMTV IGPQGADLLL TNPDIDVFVA MYHDQGHIPV KLRAGRHSAA
     LSIGAGVLFS SVGHGSGFDI AGTLLADPAP LLGAIRLVTT GTVLAPLAE
//

If you have problems or comments...

PBIL Back to PBIL home page