(data stored in ACNUC7421 zone)

SWISSPROT: Q13R52_PARXL

ID   Q13R52_PARXL            Unreviewed;       355 AA.
AC   Q13R52;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   07-JUN-2017, entry version 81.
DE   RecName: Full=tRNA 2-selenouridine synthase {ECO:0000256|SAAS:SAAS00356057};
DE            EC=2.9.1.- {ECO:0000256|SAAS:SAAS00356069};
GN   ORFNames=Bxe_B2556 {ECO:0000313|EMBL:ABE33437.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE33437.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE33437.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE33437.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S.G., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- FUNCTION: Catalyzes the transfer of selenium from selenophosphate
CC       for conversion of 2-thiouridine to 2-selenouridine at the wobble
CC       position in tRNA. {ECO:0000256|SAAS:SAAS00356073}.
CC   -!- CATALYTIC ACTIVITY: 5-methylaminomethyl-2-thiouridine +
CC       selenophosphate = 5-methylaminomethyl-2-selenouridine + phosphate.
CC       {ECO:0000256|SAAS:SAAS00356074}.
CC   -!- SUBUNIT: Monomer. {ECO:0000256|SAAS:SAAS00356061}.
CC   -!- SIMILARITY: Belongs to the 2-selenouridine synthase family.
CC       {ECO:0000256|SAAS:SAAS00548790}.
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DR   EMBL; CP000271; ABE33437.1; -; Genomic_DNA.
DR   RefSeq; WP_011490805.1; NZ_CP008762.1.
DR   ProteinModelPortal; Q13R52; -.
DR   STRING; 266265.Bxe_B2556; -.
DR   EnsemblBacteria; ABE33437; ABE33437; Bxe_B2556.
DR   GeneID; 4006948; -.
DR   KEGG; bxb:DR64_4883; -.
DR   KEGG; bxe:Bxe_B2556; -.
DR   PATRIC; fig|266265.5.peg.5147; -.
DR   eggNOG; ENOG4105CR7; Bacteria.
DR   eggNOG; COG2603; LUCA.
DR   HOGENOM; HOG000260001; -.
DR   KO; K06917; -.
DR   OMA; YCWRGGM; -.
DR   OrthoDB; POG091H04EX; -.
DR   Proteomes; UP000001817; Chromosome 2.
DR   GO; GO:0043828; F:tRNA 2-selenouridine synthase activity; IEA:InterPro.
DR   GO; GO:0070329; P:tRNA seleno-modification; IEA:InterPro.
DR   Gene3D; 3.40.250.10; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR001763; Rhodanese-like_dom.
DR   InterPro; IPR017582; tRNA_2-selenouridine_synthase.
DR   Pfam; PF00581; Rhodanese; 1.
DR   SMART; SM00450; RHOD; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF52821; SSF52821; 2.
DR   TIGRFAMs; TIGR03167; tRNA_sel_U_synt; 1.
DR   PROSITE; PS50206; RHODANESE_3; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q13R52.
DR   SWISS-2DPAGE; Q13R52.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001817};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001817};
KW   Selenium {ECO:0000256|SAAS:SAAS00035452};
KW   Transferase {ECO:0000256|SAAS:SAAS00035467}.
FT   DOMAIN       11    133       Rhodanese. {ECO:0000259|PROSITE:PS50206}.
SQ   SEQUENCE   355 AA;  39402 MW;  CABCADAE0232B66F CRC64;
     MKNLLVSLEK AGDFDEIIDV RTPLEFAEDH IPGALNAPVL SNEERVLVGT TYKQVSPFEA
     TRIGAALVAR NIAHHLETTF ADRPRNWRPL IYCWRGGKRS GSVTTLFNMI GWQARQLEGG
     YKTYRRATLD TLDSLPATFS YIALVGPTGS GKTRLLTALN AAGAQTLDLE ALASHRGSLL
     GAWAGVPQPS QKRFDTLLVT ALRTLDAARP VFVEAESRRI GSVALPLALL DTFHRGRCVE
     VLSSREDRAA FLLHDYAHLF DDPQSLKAQL QRLIGLHSRE RVTGWQRLVD DNRRAELARE
     LIERHYDPAY ARSSHEHFVQ LPHALQFNFR PNDADAVDQA SALLAQVEGS ALAVI
//

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