(data stored in ACNUC7421 zone)

SWISSPROT: Q13IV2_PARXL

ID   Q13IV2_PARXL            Unreviewed;       507 AA.
AC   Q13IV2;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   08-MAY-2019, entry version 86.
DE   SubName: Full=Succinate semialdehyde dehydrogenase {ECO:0000313|EMBL:ABE35987.1};
DE            EC=1.2.1.16 {ECO:0000313|EMBL:ABE35987.1};
GN   ORFNames=Bxe_C0060 {ECO:0000313|EMBL:ABE35987.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE35987.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE35987.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE35987.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; CP000272; ABE35987.1; -; Genomic_DNA.
DR   RefSeq; WP_011493247.1; NZ_CP008761.1.
DR   STRING; 266265.Bxe_C0060; -.
DR   EnsemblBacteria; ABE35987; ABE35987; Bxe_C0060.
DR   GeneID; 4009607; -.
DR   KEGG; bxb:DR64_8365; -.
DR   KEGG; bxe:Bxe_C0060; -.
DR   PATRIC; fig|266265.5.peg.7839; -.
DR   eggNOG; ENOG4105C26; Bacteria.
DR   eggNOG; COG1012; LUCA.
DR   HOGENOM; HOG000271509; -.
DR   KO; K15786; -.
DR   OMA; TMKRLVM; -.
DR   OrthoDB; 384611at2; -.
DR   BioCyc; BXEN266265:BXE_RS37055-MONOMER; -.
DR   Proteomes; UP000001817; Chromosome 3.
DR   GO; GO:0009013; F:succinate-semialdehyde dehydrogenase [NAD(P)+] activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.309.10; -; 1.
DR   Gene3D; 3.40.605.10; -; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016160; Ald_DH_CS_CYS.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; SSF53720; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q13IV2.
DR   SWISS-2DPAGE; Q13IV2.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001817};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU003345,
KW   ECO:0000313|EMBL:ABE35987.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001817}.
FT   DOMAIN       19    477       Aldedh. {ECO:0000259|Pfam:PF00171}.
FT   ACT_SITE    256    256       {ECO:0000256|PROSITE-ProRule:PRU10007}.
FT   ACT_SITE    290    290       {ECO:0000256|PROSITE-ProRule:PRU10008}.
SQ   SEQUENCE   507 AA;  53681 MW;  7A93F3D352DD9E85 CRC64;
     MLLGHPVLFK SLCYVDGRWV HSASAASVAV HNPADQQVLG HVPMLDAAQI TEAVGAAQRA
     FSTWRWLPVS QRSALLLRWH ELILRHQHDL AAILSLEQGK PLAEARGEIA YGASFVEWFA
     HEVRRLNGRT IPTHIDGAHL GTMIEPVGVA ALITPWNFPC AMITRKAAAA LAAGCTVVVK
     PAHETPFSAL ALAQLAEEAG FPAGVFNVVL GEPQMAMERL VGDSRVRSVS FTGSTRVGAL
     VMQAAARAGI KKTALELGGN APFIVTGDAD LDQAVRVAVA AKFQTSGQDC CAANRIFVAR
     PLYEAFVAQY SDAVKALKVG AAFEANVDVG PLMHQAAFDS TAQRVADAKA RGARITAGGG
     AHERGGWFFE PTVVADAAPG MRIYDEENFA PISAVSPFDS LDEVVERAND TEYGLAAYVC
     ARDLNTVFQL IRRLDFAMVS VNGAKFTGAP IPFGGIKSSG LGREGGAEGF EPFVETRYFC
     LGQLGLPVTE SLPAHRLAAA TGAAATA
//

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