(data stored in ACNUC7421 zone)

SWISSPROT: Q13I66_PARXL

ID   Q13I66_PARXL            Unreviewed;       486 AA.
AC   Q13I66;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   08-MAY-2019, entry version 90.
DE   SubName: Full=Succinate semialdehyde dehydrogenase {ECO:0000313|EMBL:ABE36223.1};
DE            EC=1.2.1.16 {ECO:0000313|EMBL:ABE36223.1};
GN   ORFNames=Bxe_C0300 {ECO:0000313|EMBL:ABE36223.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE36223.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE36223.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE36223.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003345}.
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DR   EMBL; CP000272; ABE36223.1; -; Genomic_DNA.
DR   RefSeq; WP_011493483.1; NZ_CP008761.1.
DR   STRING; 266265.Bxe_C0300; -.
DR   EnsemblBacteria; ABE36223; ABE36223; Bxe_C0300.
DR   GeneID; 4009671; -.
DR   KEGG; bxb:DR64_8133; -.
DR   KEGG; bxe:Bxe_C0300; -.
DR   PATRIC; fig|266265.5.peg.8080; -.
DR   eggNOG; ENOG4105C26; Bacteria.
DR   eggNOG; COG1012; LUCA.
DR   HOGENOM; HOG000271509; -.
DR   KO; K00135; -.
DR   OMA; NSFVEWF; -.
DR   OrthoDB; 384611at2; -.
DR   BioCyc; BXEN266265:BXE_RS38180-MONOMER; -.
DR   Proteomes; UP000001817; Chromosome 3.
DR   GO; GO:0009013; F:succinate-semialdehyde dehydrogenase [NAD(P)+] activity; IEA:UniProtKB-EC.
DR   GO; GO:0009450; P:gamma-aminobutyric acid catabolic process; IEA:InterPro.
DR   Gene3D; 3.40.309.10; -; 1.
DR   Gene3D; 3.40.605.10; -; 1.
DR   InterPro; IPR016161; Ald_DH/histidinol_DH.
DR   InterPro; IPR016163; Ald_DH_C.
DR   InterPro; IPR016160; Ald_DH_CS_CYS.
DR   InterPro; IPR029510; Ald_DH_CS_GLU.
DR   InterPro; IPR016162; Ald_DH_N.
DR   InterPro; IPR015590; Aldehyde_DH_dom.
DR   InterPro; IPR010102; Succ_semiAld_DH.
DR   Pfam; PF00171; Aldedh; 1.
DR   SUPFAM; SSF53720; SSF53720; 1.
DR   TIGRFAMs; TIGR01780; SSADH; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q13I66.
DR   SWISS-2DPAGE; Q13I66.
KW   Complete proteome {ECO:0000313|Proteomes:UP000001817};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU003345,
KW   ECO:0000313|EMBL:ABE36223.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001817}.
FT   DOMAIN       23    480       Aldedh. {ECO:0000259|Pfam:PF00171}.
FT   ACT_SITE    259    259       {ECO:0000256|PROSITE-ProRule:PRU10007}.
FT   ACT_SITE    293    293       {ECO:0000256|PROSITE-ProRule:PRU10008}.
SQ   SEQUENCE   486 AA;  52127 MW;  AB6FED2B48100958 CRC64;
     MRYSIKLNDQ ALLRQHAYIN GEWQTADNGS TFTITDPSSG DLLAQVPMMG AAEARRAIHA
     ACIAWSVWRK KTAKDRAIVM RRWFNLVLEN ADDLATILTA EQGKPLAEAK GEIAYAASFI
     EWFAEEGKRV SGDTPATPDA DKRIIVTKEP IGVCAAITPW NFPAAMITRK VAPALAAGCT
     IVVKPAEATP LTALALAVLA ERAGIPSGVL NVITGDPRAI GAELTANPGV RKLSFTGSTA
     IGRMLMAQSA PTIKKVTLEL GGNAPFIVFD DADIDNAVEG AVVSKYRNSG QTCVCPNRFY
     VHDAVYDAFV EKLSKAVFEL KVGSGRDPGV SIGPLISEAA VKKVEAHIAD ALQKGAKLEV
     GGARHELGHS FFQPTVLSDV TPDMMLSREE TFGPLAAVSR FSSEDEVVRL ANDTEYGLAA
     YFYSRNIARV WRLAEALEYG MVGINTGLIS NEVAPFGGVK ESGIGREGSR YGIEDYLVIK
     YLCLAS
//

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