(data stored in ACNUC7421 zone)

SWISSPROT: Q13HX0_PARXL

ID   Q13HX0_PARXL            Unreviewed;       249 AA.
AC   Q13HX0;
DT   22-AUG-2006, integrated into UniProtKB/TrEMBL.
DT   22-AUG-2006, sequence version 1.
DT   08-MAY-2019, entry version 69.
DE   RecName: Full=Acyl-homoserine-lactone synthase {ECO:0000256|RuleBase:RU361135};
DE            EC=2.3.1.184 {ECO:0000256|RuleBase:RU361135};
DE   AltName: Full=Autoinducer synthesis protein {ECO:0000256|RuleBase:RU361135};
GN   ORFNames=Bxe_C0415 {ECO:0000313|EMBL:ABE36319.1};
OS   Paraburkholderia xenovorans (strain LB400).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Paraburkholderia.
OX   NCBI_TaxID=266265 {ECO:0000313|EMBL:ABE36319.1, ECO:0000313|Proteomes:UP000001817};
RN   [1] {ECO:0000313|EMBL:ABE36319.1, ECO:0000313|Proteomes:UP000001817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LB400 {ECO:0000313|EMBL:ABE36319.1,
RC   ECO:0000313|Proteomes:UP000001817};
RX   PubMed=17030797; DOI=10.1073/pnas.0606924103;
RA   Chain P.S., Denef V.J., Konstantinidis K.T., Vergez L.M., Agullo L.,
RA   Reyes V.L., Hauser L., Cordova M., Gomez L., Gonzalez M., Land M.,
RA   Lao V., Larimer F., LiPuma J.J., Mahenthiralingam E., Malfatti S.A.,
RA   Marx C.J., Parnell J.J., Ramette A., Richardson P., Seeger M.,
RA   Smith D., Spilker T., Sul W.J., Tsoi T.V., Ulrich L.E., Zhulin I.B.,
RA   Tiedje J.M.;
RT   "Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73-Mbp
RT   genome shaped for versatility.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15280-15287(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a fatty acyl-[ACP] + S-adenosyl-L-methionine = an N-acyl-
CC         L-homoserine lactone + H(+) + holo-[ACP] + S-methyl-5'-
CC         thioadenosine; Xref=Rhea:RHEA:10096, Rhea:RHEA-COMP:9685,
CC         Rhea:RHEA-COMP:14125, ChEBI:CHEBI:15378, ChEBI:CHEBI:17509,
CC         ChEBI:CHEBI:55474, ChEBI:CHEBI:59789, ChEBI:CHEBI:64479,
CC         ChEBI:CHEBI:138651; EC=2.3.1.184;
CC         Evidence={ECO:0000256|RuleBase:RU361135};
CC   -!- SIMILARITY: Belongs to the autoinducer synthase family.
CC       {ECO:0000256|PROSITE-ProRule:PRU00533,
CC       ECO:0000256|RuleBase:RU361135}.
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DR   EMBL; CP000272; ABE36319.1; -; Genomic_DNA.
DR   STRING; 266265.Bxe_C0415; -.
DR   EnsemblBacteria; ABE36319; ABE36319; Bxe_C0415.
DR   KEGG; bxb:DR64_8028; -.
DR   KEGG; bxe:Bxe_C0415; -.
DR   eggNOG; COG3916; LUCA.
DR   HOGENOM; HOG000207772; -.
DR   KO; K20250; -.
DR   OMA; GQEYDRY; -.
DR   Proteomes; UP000001817; Chromosome 3.
DR   GO; GO:0061579; F:N-acyl homoserine lactone synthase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0009372; P:quorum sensing; IEA:UniProtKB-UniRule.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR018311; Autoind_synth_CS.
DR   InterPro; IPR001690; Autoind_synthase.
DR   PANTHER; PTHR39322; PTHR39322; 1.
DR   Pfam; PF00765; Autoind_synth; 1.
DR   PRINTS; PR01549; AUTOINDCRSYN.
DR   SUPFAM; SSF55729; SSF55729; 1.
DR   PROSITE; PS00949; AUTOINDUCER_SYNTH_1; 1.
DR   PROSITE; PS51187; AUTOINDUCER_SYNTH_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q13HX0.
DR   SWISS-2DPAGE; Q13HX0.
KW   Autoinducer synthesis {ECO:0000256|PROSITE-ProRule:PRU00533,
KW   ECO:0000256|RuleBase:RU361135};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001817};
KW   Quorum sensing {ECO:0000256|PROSITE-ProRule:PRU00533,
KW   ECO:0000256|RuleBase:RU361135};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001817};
KW   S-adenosyl-L-methionine {ECO:0000256|RuleBase:RU361135};
KW   Transferase {ECO:0000256|RuleBase:RU361135}.
SQ   SEQUENCE   249 AA;  26858 MW;  22CA2D7372F46D70 CRC64;
     MSFVVAGRLD DLPSHIRHDL GTFRHQVFIQ RLHWEIPGVP RDAISEWDEF DGGSTVHLVA
     LSANDRVCGC ARLMPTTGPY LLRDVFPELT GAGSPPSSPS VWEMSRFAGS GLTDHRTGSA
     SGMSLFPYAM SLARSFGATR LIGVVTRPVA RLYRRFGLDL RHIGASSSPG HADIVACAID
     LTTATFDKLQ CDADSLLRSI SCLGHLPRPQ QSLCAPLKAK EEGLHSAVSR DETSFPACGS
     GTARTERAI
//

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