(data stored in ACNUC7421 zone)

SWISSPROT: Q13EP7_RHOPS

ID   Q13EP7_RHOPS            Unreviewed;      1159 AA.
AC   Q13EP7;
DT   31-OCT-2006, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2006, sequence version 1.
DT   08-MAY-2019, entry version 93.
DE   SubName: Full=DNA helicase/exodeoxyribonuclease V, subunit A {ECO:0000313|EMBL:ABE37442.1};
DE            EC=3.1.11.5 {ECO:0000313|EMBL:ABE37442.1};
GN   OrderedLocusNames=RPD_0202 {ECO:0000313|EMBL:ABE37442.1};
OS   Rhodopseudomonas palustris (strain BisB5).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Bradyrhizobiaceae; Rhodopseudomonas.
OX   NCBI_TaxID=316057 {ECO:0000313|EMBL:ABE37442.1, ECO:0000313|Proteomes:UP000001818};
RN   [1] {ECO:0000313|EMBL:ABE37442.1, ECO:0000313|Proteomes:UP000001818}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BisB5 {ECO:0000313|EMBL:ABE37442.1,
RC   ECO:0000313|Proteomes:UP000001818};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Pelletier D.A., Kyrpides N.,
RA   Lykidis A., Oda Y., Harwood C.S., Richardson P.;
RT   "Complete sequence of Rhodopseudomonas palustris BisB5.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000256|SAAS:SAAS01129065};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|SAAS:SAAS01099290};
CC   -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC       {ECO:0000256|SAAS:SAAS00709641}.
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DR   EMBL; CP000283; ABE37442.1; -; Genomic_DNA.
DR   STRING; 316057.RPD_0202; -.
DR   EnsemblBacteria; ABE37442; ABE37442; RPD_0202.
DR   KEGG; rpd:RPD_0202; -.
DR   eggNOG; ENOG4107QKA; Bacteria.
DR   eggNOG; COG1074; LUCA.
DR   HOGENOM; HOG000143994; -.
DR   KO; K16898; -.
DR   OMA; KQSIYRW; -.
DR   Proteomes; UP000001818; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0008854; F:exodeoxyribonuclease V activity; IEA:UniProtKB-EC.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.320.10; -; 1.
DR   InterPro; IPR014151; DNA_helicase_AddA.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR011604; Exonuc_phg/RecB_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038726; PDDEXK_AddAB-type.
DR   InterPro; IPR011335; Restrct_endonuc-II-like.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   InterPro; IPR034739; UvrD/AddA_N.
DR   PANTHER; PTHR11070; PTHR11070; 1.
DR   Pfam; PF12705; PDDEXK_1; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF52980; SSF52980; 1.
DR   TIGRFAMs; TIGR02784; addA_alphas; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
DR   PROSITE; PS51217; UVRD_HELICASE_CTER; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q13EP7.
DR   SWISS-2DPAGE; Q13EP7.
KW   ATP-binding {ECO:0000256|SAAS:SAAS00146071};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001818};
KW   DNA damage {ECO:0000256|SAAS:SAAS01099294};
KW   DNA repair {ECO:0000256|SAAS:SAAS01099287};
KW   DNA-binding {ECO:0000256|SAAS:SAAS00745286};
KW   Exonuclease {ECO:0000256|SAAS:SAAS01033115};
KW   Helicase {ECO:0000256|SAAS:SAAS00553650, ECO:0000313|EMBL:ABE37442.1};
KW   Hydrolase {ECO:0000256|SAAS:SAAS00146062,
KW   ECO:0000313|EMBL:ABE37442.1};
KW   Nuclease {ECO:0000256|SAAS:SAAS01033141};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS00145996}.
FT   DOMAIN        8    489       UvrD-like helicase ATP-binding.
FT                                {ECO:0000259|PROSITE:PS51198}.
FT   DOMAIN      519    794       UvrD-like helicase C-terminal.
FT                                {ECO:0000259|PROSITE:PS51217}.
FT   COILED      319    339       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1159 AA;  127205 MW;  E1D845C177C2C021 CRC64;
     MSAPRSIPDQ ARERQILASD PSASVFVSAN AGSGKTHVLV QRVIRLLLDG VPPERILCIT
     FTKAAAANMA ERVFTTLGRW VTLDDEALTA AIKATGIKSV GPSLLAQARK LFACALETPG
     GLKVQTIHAL CTRLLQQFPF EANVPARFSV LDDRDQAELM QRASLAVLLQ AAAAPDSAAG
     RALTLAMTSA ADVTFREVVQ EACTRRDRFL AWITQAGGVD GAMAQLSATL GVAPQDRCED
     VERDILDGPN LPRAQWSTAA AMFESGSAND QAQAKRLRAA LALSDVAQLD KYCEVFFTKD
     GPRKSLATKK IADAAPGFVE DLKREGARLE DLLERRRALL MRERTRALLV IAADVAERIR
     REKQERGLLD YDDLIDKTLA MLDSGASSWV HFKLDRGVDH VLIDEAQDTS PKQWDIVAHL
     IAEFTAGEGA RDGVRRTVFA VGDEKQSIFS FQGAVPKEFA ERRDLLQRRF HGAGLNFEKV
     SFNYSFRSGA TILQSVDHVF RDPDIYRSIH ADAAYPLHQS LADAGPSVID LWPLELPDDK
     QNIEGWRAPF DAVSETSPEV RLAQKVQAEI ASLIAGGTMT GSLGDRRRLR FGDVLVLVRR
     RGSAFDAVIQ ALKRGGIPVA GADRLKLTEH IAIIDLMNLA DALLLPQDDL ALAVALKSPL
     FGLDDDDLFR LAWRRKGSLR HALREKAAGD AKLATALQRL DACAERSQTD TPFGFYAWLL
     GGVGGRARIL RRLGPEANDA LDEFLELALS YEQKAAPSLQ GFMAWLRAAD TEIKRDMEIS
     RDEVRVMTVH GAKGLEAPVV FLVDTTSSPS DTQRLNLIRL PGGNAQPGSV GAMVWAGRKS
     NDPRVVEQAR AEMVSETEDE YRRLLYVAMT RAADRLIVGG CMPGNRNEVR ALSWYDLISK
     GLENSGLTMR TAPPDGAVKR YCRPEDEVTE IAPSEQAPAA PPLVMPDWLH KAAPALRRPD
     NLLRPSDPDD ADHRRIRRGE TEAQRQRALQ RGTLVHRLLQ SLPDLPADIR ANAADRFLLR
     NADDWSPQER DALAARVLEV ISDDRFAAVF APGSRAEVPI VGRLQRHGEP VLISGQIDRL
     VVTDAEVLIV DYKTNHAPPR SLAETPPAYV RQLALYRAVL SLLYPQRIVR AALLWTEAPE
     IMEISAPALD AEQAALTVA
//

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