(data stored in ACNUC7421 zone)

SWISSPROT: Q13DT4_RHOPS

ID   Q13DT4_RHOPS            Unreviewed;       315 AA.
AC   Q13DT4;
DT   31-OCT-2006, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2006, sequence version 1.
DT   08-MAY-2019, entry version 82.
DE   RecName: Full=Signal recognition particle receptor FtsY {ECO:0000256|HAMAP-Rule:MF_00920};
DE            Short=SRP receptor {ECO:0000256|HAMAP-Rule:MF_00920};
GN   Name=ftsY {ECO:0000256|HAMAP-Rule:MF_00920};
GN   OrderedLocusNames=RPD_0517 {ECO:0000313|EMBL:ABE37755.1};
OS   Rhodopseudomonas palustris (strain BisB5).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Bradyrhizobiaceae; Rhodopseudomonas.
OX   NCBI_TaxID=316057 {ECO:0000313|EMBL:ABE37755.1, ECO:0000313|Proteomes:UP000001818};
RN   [1] {ECO:0000313|EMBL:ABE37755.1, ECO:0000313|Proteomes:UP000001818}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BisB5 {ECO:0000313|EMBL:ABE37755.1,
RC   ECO:0000313|Proteomes:UP000001818};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Pelletier D.A., Kyrpides N.,
RA   Lykidis A., Oda Y., Harwood C.S., Richardson P.;
RT   "Complete sequence of Rhodopseudomonas palustris BisB5.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in targeting and insertion of nascent membrane
CC       proteins into the cytoplasmic membrane. Acts as a receptor for the
CC       complex formed by the signal recognition particle (SRP) and the
CC       ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to
CC       the transfer of the RNC complex to the Sec translocase for
CC       insertion into the membrane, the hydrolysis of GTP by both Ffh and
CC       FtsY, and the dissociation of the SRP-FtsY complex into the
CC       individual components. {ECO:0000256|HAMAP-Rule:MF_00920}.
CC   -!- SUBUNIT: Part of the signal recognition particle protein
CC       translocation system, which is composed of SRP and FtsY. SRP is a
CC       ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.
CC       {ECO:0000256|HAMAP-Rule:MF_00920}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC       Rule:MF_00920}; Peripheral membrane protein {ECO:0000256|HAMAP-
CC       Rule:MF_00920}; Cytoplasmic side {ECO:0000256|HAMAP-
CC       Rule:MF_00920}. Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00920}.
CC   -!- SIMILARITY: Belongs to the GTP-binding SRP family. FtsY subfamily.
CC       {ECO:0000256|HAMAP-Rule:MF_00920}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000283; ABE37755.1; -; Genomic_DNA.
DR   RefSeq; WP_011500942.1; NC_007958.1.
DR   STRING; 316057.RPD_0517; -.
DR   EnsemblBacteria; ABE37755; ABE37755; RPD_0517.
DR   KEGG; rpd:RPD_0517; -.
DR   eggNOG; ENOG4105CCP; Bacteria.
DR   eggNOG; COG0552; LUCA.
DR   HOGENOM; HOG000036278; -.
DR   KO; K03110; -.
DR   OMA; GISDQFQ; -.
DR   OrthoDB; 656414at2; -.
DR   BioCyc; RPAL316057:RPD_RS02650-MONOMER; -.
DR   Proteomes; UP000001818; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0031226; C:intrinsic component of plasma membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003924; F:GTPase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; IEA:InterPro.
DR   Gene3D; 1.20.120.140; -; 1.
DR   HAMAP; MF_00920; FtsY; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR013822; Signal_recog_particl_SRP54_hlx.
DR   InterPro; IPR004390; SR_rcpt_FtsY.
DR   InterPro; IPR036225; SRP/SRP_N.
DR   InterPro; IPR000897; SRP54_GTPase_dom.
DR   InterPro; IPR042101; SRP54_N_sf.
DR   PANTHER; PTHR43134:SF7; PTHR43134:SF7; 1.
DR   Pfam; PF00448; SRP54; 1.
DR   Pfam; PF02881; SRP54_N; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00962; SRP54; 1.
DR   SMART; SM00963; SRP54_N; 1.
DR   SUPFAM; SSF47364; SSF47364; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00064; ftsY; 1.
DR   PROSITE; PS00300; SRP54; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q13DT4.
DR   SWISS-2DPAGE; Q13DT4.
KW   Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_00920};
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_00920};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001818};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00920};
KW   GTP-binding {ECO:0000256|HAMAP-Rule:MF_00920};
KW   Membrane {ECO:0000256|HAMAP-Rule:MF_00920};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00920};
KW   Receptor {ECO:0000256|HAMAP-Rule:MF_00920}.
FT   DOMAIN      284    297       SRP54. {ECO:0000259|PROSITE:PS00300}.
FT   NP_BIND     117    124       GTP. {ECO:0000256|HAMAP-Rule:MF_00920}.
FT   NP_BIND     199    203       GTP. {ECO:0000256|HAMAP-Rule:MF_00920}.
FT   NP_BIND     263    266       GTP. {ECO:0000256|HAMAP-Rule:MF_00920}.
SQ   SEQUENCE   315 AA;  33496 MW;  9DBBA6F98DD851F2 CRC64;
     MSDTPETQKP SWWRRLSSGL KRTSSSIGTA LSEFISKRKL DRAMLDEIED VLLRADLGTE
     VASRISDAVG EGRYDKMISA SDVKEIVASE VEKVLAPVAK PLVIDDAKKP FVVLVVGVNG
     SGKTTTIGKL SARFAAEGRK VMMAAGDTFR AAAIEQLKVW GERTGTPVIA GAQGSDSASL
     AFNALTAAKE QGRDVLLIDT AGRLQNRKEL MSELEKVVRV IKKVDDTAPH AVLLVLDATV
     GQNALSQVEA FTRTAGVTGL VMTKLDGTAR GGILVAIAEK HKLPVHFIGV GEGVEDLSPF
     TARDFAQAIA GTETQ
//

If you have problems or comments...

PBIL Back to PBIL home page