(data stored in ACNUC7421 zone)

SWISSPROT: Q13DG8_RHOPS

ID   Q13DG8_RHOPS            Unreviewed;       323 AA.
AC   Q13DG8;
DT   31-OCT-2006, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2006, sequence version 1.
DT   16-JAN-2019, entry version 73.
DE   RecName: Full=Cobalamin biosynthesis protein CobD {ECO:0000256|HAMAP-Rule:MF_00024};
GN   Name=cobD {ECO:0000256|HAMAP-Rule:MF_00024};
GN   OrderedLocusNames=RPD_0633 {ECO:0000313|EMBL:ABE37871.1};
OS   Rhodopseudomonas palustris (strain BisB5).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Bradyrhizobiaceae; Rhodopseudomonas.
OX   NCBI_TaxID=316057 {ECO:0000313|EMBL:ABE37871.1, ECO:0000313|Proteomes:UP000001818};
RN   [1] {ECO:0000313|EMBL:ABE37871.1, ECO:0000313|Proteomes:UP000001818}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BisB5 {ECO:0000313|EMBL:ABE37871.1,
RC   ECO:0000313|Proteomes:UP000001818};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Pelletier D.A., Kyrpides N.,
RA   Lykidis A., Oda Y., Harwood C.S., Richardson P.;
RT   "Complete sequence of Rhodopseudomonas palustris BisB5.";
RL   Submitted (MAR-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Converts cobyric acid to cobinamide by the addition of
CC       aminopropanol on the F carboxylic group. {ECO:0000256|HAMAP-
CC       Rule:MF_00024}.
CC   -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC       {ECO:0000256|HAMAP-Rule:MF_00024}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-
CC       Rule:MF_00024}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC       Rule:MF_00024}.
CC   -!- SIMILARITY: Belongs to the CobD/CbiB family. {ECO:0000256|HAMAP-
CC       Rule:MF_00024}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|HAMAP-Rule:MF_00024}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000283; ABE37871.1; -; Genomic_DNA.
DR   RefSeq; WP_011501058.1; NC_007958.1.
DR   STRING; 316057.RPD_0633; -.
DR   EnsemblBacteria; ABE37871; ABE37871; RPD_0633.
DR   KEGG; rpd:RPD_0633; -.
DR   eggNOG; ENOG4105DH2; Bacteria.
DR   eggNOG; COG1270; LUCA.
DR   HOGENOM; HOG000290070; -.
DR   KO; K02227; -.
DR   OMA; DAMVGHR; -.
DR   OrthoDB; 2029688at2; -.
DR   BioCyc; RPAL316057:RPD_RS03245-MONOMER; -.
DR   UniPathway; UPA00148; -.
DR   Proteomes; UP000001818; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015420; F:cobalamin-transporting ATPase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0048472; F:threonine-phosphate decarboxylase activity; IEA:InterPro.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR   HAMAP; MF_00024; CobD_CbiB; 1.
DR   InterPro; IPR004485; Cobalamin_biosynth_CobD/CbiB.
DR   PANTHER; PTHR34308; PTHR34308; 1.
DR   Pfam; PF03186; CobD_Cbib; 1.
DR   TIGRFAMs; TIGR00380; cobD; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q13DG8.
DR   SWISS-2DPAGE; Q13DG8.
KW   Cell membrane {ECO:0000256|HAMAP-Rule:MF_00024};
KW   Cobalamin biosynthesis {ECO:0000256|HAMAP-Rule:MF_00024};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001818};
KW   Ligase {ECO:0000313|EMBL:ABE37871.1};
KW   Membrane {ECO:0000256|HAMAP-Rule:MF_00024};
KW   Transmembrane {ECO:0000256|HAMAP-Rule:MF_00024};
KW   Transmembrane helix {ECO:0000256|HAMAP-Rule:MF_00024}.
FT   TRANSMEM     32     49       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_00024}.
FT   TRANSMEM     61     81       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_00024}.
FT   TRANSMEM    163    181       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_00024}.
FT   TRANSMEM    304    322       Helical. {ECO:0000256|HAMAP-Rule:
FT                                MF_00024}.
SQ   SEQUENCE   323 AA;  34273 MW;  696BF79EC5DEC57F CRC64;
     MLLDSNALLI VVAALLIDAV IGDPDWLWKR LAHPVVLIGA LIGWLDGVLN RESWSDGRRK
     SAGILAILAV IAVTGSIGFF IEAPLRQGWG GWGAIAAVAA TLIAQRSLYD HVARVRDAFA
     AGGLEAAREK VALIVGRDPQ TLDEAGVSRA AIESCAENFS DGVVAPVFWL AVLGLPGLLI
     YKGINTADSM IGHLNPRYRA FGWAAARLDD LVNWIPARLS GVLIALAAPV VRGSIKQSFA
     VMRRDARKHR SPNAGWPEAA MAGALGIALA GPRIYGGQLT DDPFLNDGAR AAATPDDIRR
     ATRVLIAVCV LQAAIYAALW FVL
//

If you have problems or comments...

PBIL Back to PBIL home page