(data stored in ACNUC30630 zone)

SWISSPROT: IF3_MYXXD

ID   IF3_MYXXD               Reviewed;         247 AA.
AC   Q1DES4;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2006, sequence version 1.
DT   11-DEC-2019, entry version 92.
DE   RecName: Full=Translation initiation factor IF-3 {ECO:0000255|HAMAP-Rule:MF_00080};
GN   Name=infC {ECO:0000255|HAMAP-Rule:MF_00080}; OrderedLocusNames=MXAN_0581;
OS   Myxococcus xanthus (strain DK 1622).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Myxococcaceae; Myxococcus.
OX   NCBI_TaxID=246197;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DK 1622;
RX   PubMed=17015832; DOI=10.1073/pnas.0607335103;
RA   Goldman B.S., Nierman W.C., Kaiser D., Slater S.C., Durkin A.S., Eisen J.,
RA   Ronning C.M., Barbazuk W.B., Blanchard M., Field C., Halling C., Hinkle G.,
RA   Iartchuk O., Kim H.S., Mackenzie C., Madupu R., Miller N., Shvartsbeyn A.,
RA   Sullivan S.A., Vaudin M., Wiegand R., Kaplan H.B.;
RT   "Evolution of sensory complexity recorded in a myxobacterial genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15200-15205(2006).
CC   -!- FUNCTION: IF-3 binds to the 30S ribosomal subunit and shifts the
CC       equilibrum between 70S ribosomes and their 50S and 30S subunits in
CC       favor of the free subunits, thus enhancing the availability of 30S
CC       subunits on which protein synthesis initiation begins.
CC       {ECO:0000255|HAMAP-Rule:MF_00080}.
CC   -!- SUBUNIT: Monomer. {ECO:0000255|HAMAP-Rule:MF_00080}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00080}.
CC   -!- SIMILARITY: Belongs to the IF-3 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00080}.
DR   EMBL; CP000113; ABF88845.1; -; Genomic_DNA.
DR   RefSeq; WP_011550712.1; NC_008095.1.
DR   SMR; Q1DES4; -.
DR   STRING; 246197.MXAN_0581; -.
DR   EnsemblBacteria; ABF88845; ABF88845; MXAN_0581.
DR   GeneID; 41358060; -.
DR   KEGG; mxa:MXAN_0581; -.
DR   eggNOG; ENOG4108UUX; Bacteria.
DR   eggNOG; COG0290; LUCA.
DR   HOGENOM; HOG000035157; -.
DR   KO; K02520; -.
DR   OMA; PNKEMIK; -.
DR   BioCyc; MXAN246197:G1G53-570-MONOMER; -.
DR   Proteomes; UP000002402; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.10.20.80; -; 1.
DR   Gene3D; 3.30.110.10; -; 1.
DR   HAMAP; MF_00080; IF_3; 1.
DR   InterPro; IPR036788; T_IF-3_C_sf.
DR   InterPro; IPR036787; T_IF-3_N_sf.
DR   InterPro; IPR019813; Translation_initiation_fac3_CS.
DR   InterPro; IPR001288; Translation_initiation_fac_3.
DR   InterPro; IPR019815; Translation_initiation_fac_3_C.
DR   InterPro; IPR019814; Translation_initiation_fac_3_N.
DR   PANTHER; PTHR10938; PTHR10938; 1.
DR   Pfam; PF00707; IF3_C; 1.
DR   Pfam; PF05198; IF3_N; 1.
DR   SUPFAM; SSF54364; SSF54364; 1.
DR   SUPFAM; SSF55200; SSF55200; 1.
DR   TIGRFAMs; TIGR00168; infC; 1.
DR   PROSITE; PS00938; IF3; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q1DES4.
DR   SWISS-2DPAGE; Q1DES4.
KW   Cytoplasm; Initiation factor; Protein biosynthesis.
FT   CHAIN           1..247
FT                   /note="Translation initiation factor IF-3"
FT                   /id="PRO_1000004545"
SQ   SEQUENCE   247 AA;  27145 MW;  6052DAC6407FAEA7 CRC64;
     MIREQRSSRG GSRDQRTNRR IRAREVRVVG SDGSQLGVMP LEAALDRART EGLDLVEISP
     MASPPVCKIM DYGKFKYEEK KKASEAKRAQ VTVLLKEVKL RPKTEEHDYE FKVRNTRRFI
     EDGNKAKVVI QFRGREITHR EQGTAILDDV AKDLKDVAVV EQMPRMEGRL MFMILAPTPK
     VAQKARELVR QAATAAKRPP PPGAPGAGKS AAGASSGAEE KAEETAEEKK EAQAAPAAAE
     AQSPTAS
//

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