(data stored in ACNUC9543 zone)

SWISSPROT: UGPA_YERPA

ID   UGPA_YERPA              Reviewed;         295 AA.
AC   Q1CBH4;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2006, sequence version 1.
DT   11-DEC-2019, entry version 74.
DE   RecName: Full=sn-glycerol-3-phosphate transport system permease protein UgpA;
GN   Name=ugpA; OrderedLocusNames=YPA_0229;
OS   Yersinia pestis bv. Antiqua (strain Antiqua).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=360102;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Antiqua;
RX   PubMed=16740952; DOI=10.1128/jb.00124-06;
RA   Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M.,
RA   Worsham P., Chu M.C., Andersen G.L.;
RT   "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516:
RT   evidence of gene reduction in an emerging pathogen.";
RL   J. Bacteriol. 188:4453-4463(2006).
CC   -!- FUNCTION: Part of the binding-protein-dependent transport system for
CC       sn-glycerol-3-phosphate; probably responsible for the translocation of
CC       the substrate across the membrane. {ECO:0000250}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (UgpC),
CC       two transmembrane proteins (UgpA and UgpE) and a solute-binding protein
CC       (UgpB). {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. UgpAE subfamily. {ECO:0000305}.
DR   EMBL; CP000308; ABG12198.1; -; Genomic_DNA.
DR   RefSeq; WP_002211521.1; NZ_CP009906.1.
DR   SMR; Q1CBH4; -.
DR   EnsemblBacteria; ABG12198; ABG12198; YPA_0229.
DR   KEGG; ypa:YPA_0229; -.
DR   HOGENOM; HOG000220406; -.
DR   KO; K05814; -.
DR   OMA; LWYSVQS; -.
DR   Proteomes; UP000001971; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q1CBH4.
DR   SWISS-2DPAGE; Q1CBH4.
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..295
FT                   /note="sn-glycerol-3-phosphate transport system permease
FT                   protein UgpA"
FT                   /id="PRO_0000292835"
FT   TOPO_DOM        1..11
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TOPO_DOM        33..80
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TOPO_DOM        102..109
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        110..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TOPO_DOM        131..157
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        158..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TOPO_DOM        179..207
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        208..228
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TOPO_DOM        229..262
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        263..283
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TOPO_DOM        284..295
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          72..284
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   295 AA;  32503 MW;  98635DF35C16CAC5 CRC64;
     MSPSRPGFSC SWLPYLLVLP QLAITAIFFL WPAGEALWYS VQTLDPFGLS SEFVGLSNFI
     QLFQDEYYLA SFYTTLIFSA LVAGIGLIVS LFLAAMVNYV LRGSRLYQTL LILPYAVAPA
     VAAVLWIFLF DPGLGLITHA LAKLGYSWNH AQNSGQAMFL VVLASVWKQI SYNFLFFLAA
     LQSIPKSLVE AAAIDGAGPV RRFFNLVLPL ISPVSFFLLV VNLVYAFFDT FPVIDAATGG
     GPVQATTTLI YKIYREGFAG LDLSSSAAQS VILMLLVIGL TVIQFRFVER KVRYQ
//

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