(data stored in ACNUC9543 zone)

SWISSPROT: A0A0E1NTF1_YERPA

ID   A0A0E1NTF1_YERPA        Unreviewed;       388 AA.
AC   A0A0E1NTF1;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   07-NOV-2018, entry version 25.
DE   SubName: Full=N-acetylglucosamine 6-phosphate deacetylase {ECO:0000313|EMBL:ABG12400.1};
DE            EC=3.5.1.25 {ECO:0000313|EMBL:ABG12400.1};
GN   OrderedLocusNames=YPA_0432 {ECO:0000313|EMBL:ABG12400.1};
OS   Yersinia pestis bv. Antiqua (strain Antiqua).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=360102 {ECO:0000313|EMBL:ABG12400.1, ECO:0000313|Proteomes:UP000001971};
RN   [1] {ECO:0000313|EMBL:ABG12400.1, ECO:0000313|Proteomes:UP000001971}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Antiqua {ECO:0000313|EMBL:ABG12400.1,
RC   ECO:0000313|Proteomes:UP000001971};
RX   PubMed=16740952; DOI=10.1128/JB.00124-06;
RA   Chain P.S., Hu P., Malfatti S.A., Radnedge L., Larimer F.,
RA   Vergez L.M., Worsham P., Chu M.C., Andersen G.L.;
RT   "Complete genome sequence of Yersinia pestis strains Antiqua and
RT   Nepal516: evidence of gene reduction in an emerging pathogen.";
RL   J. Bacteriol. 188:4453-4463(2006).
CC   -!- COFACTOR:
CC       Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240;
CC         Evidence={ECO:0000256|PIRSR:PIRSR038994-3};
CC       Note=Binds 1 divalent metal cation per subunit.
CC       {ECO:0000256|PIRSR:PIRSR038994-3};
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases
CC       superfamily. NagA family. {ECO:0000256|PIRNR:PIRNR038994}.
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DR   EMBL; CP000308; ABG12400.1; -; Genomic_DNA.
DR   RefSeq; WP_002209882.1; NZ_CP009906.1.
DR   EnsemblBacteria; ABG12400; ABG12400; YPA_0432.
DR   EnsemblBacteria; AJJ78568; AJJ78568; CH58_3280.
DR   KEGG; ypa:YPA_0432; -.
DR   PATRIC; fig|360102.15.peg.3446; -.
DR   KO; K02079; -.
DR   OMA; HIHGRAG; -.
DR   Proteomes; UP000001971; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0047419; F:N-acetylgalactosamine-6-phosphate deacetylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008448; F:N-acetylglucosamine-6-phosphate deacetylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006044; P:N-acetylglucosamine metabolic process; IEA:InterPro.
DR   CDD; cd00854; NagA; 1.
DR   Gene3D; 2.30.40.10; -; 1.
DR   InterPro; IPR006680; Amidohydro-rel.
DR   InterPro; IPR003764; GlcNAc_6-P_deAcase.
DR   InterPro; IPR011059; Metal-dep_hydrolase_composite.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR11113:SF1; PTHR11113:SF1; 1.
DR   Pfam; PF01979; Amidohydro_1; 1.
DR   PIRSF; PIRSF038994; NagA; 1.
DR   SUPFAM; SSF51338; SSF51338; 1.
DR   SUPFAM; SSF51556; SSF51556; 1.
DR   TIGRFAMs; TIGR00221; nagA; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0A0E1NTF1.
DR   SWISS-2DPAGE; A0A0E1NTF1.
KW   Carbohydrate metabolism {ECO:0000256|PIRNR:PIRNR038994};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001971};
KW   Hydrolase {ECO:0000256|PIRNR:PIRNR038994,
KW   ECO:0000313|EMBL:ABG12400.1};
KW   Metal-binding {ECO:0000256|PIRSR:PIRSR038994-3}.
FT   ACT_SITE    277    277       Proton donor/acceptor.
FT                                {ECO:0000256|PIRSR:PIRSR038994-1}.
FT   METAL       133    133       Divalent metal cation.
FT                                {ECO:0000256|PIRSR:PIRSR038994-3}.
FT   METAL       199    199       Divalent metal cation; via tele nitrogen.
FT                                {ECO:0000256|PIRSR:PIRSR038994-3}.
FT   METAL       220    220       Divalent metal cation; via tele nitrogen.
FT                                {ECO:0000256|PIRSR:PIRSR038994-3}.
SQ   SEQUENCE   388 AA;  41595 MW;  321662DFBCC2D598 CRC64;
     MRTAYLADRT FTPQGIETGV AVIVEQGEIV AVTRELPADA EIVHLTGKTL IPGLIDIHIH
     GRQGADVMDA SAEALRTIAR ALPQTGVVAW VGTTVSAPIQ DIFAALAQVR DFIADPDNAR
     DTRTATLLGS FLEGPYFTAP FRGSHPEKYL TTPTPQELEQ LRHSAGNTLL RAAIAPESPE
     ALAAIRWLVN HGIKTSVAHT AANFEQVTAA YQQGADCGVH LYNGMSGLHH REPGCCGAVL
     YHDMLAELIA DGIHVHPVMM NLAYRMKGYR RIALITDCMR AGGLGEGRYL LGAQHITVRQ
     GEARTDDGSL AGSTCSLDQA LRNMIQHAQV PEWEAVQMAS AVPAAYLGLA STLGSIQMGA
     QASMVVMESD FTVAATLIKG EWAYRHSA
//

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