(data stored in ACNUC9543 zone)

SWISSPROT: A0A0E1NZQ2_YERPA

ID   A0A0E1NZQ2_YERPA        Unreviewed;      1037 AA.
AC   A0A0E1NZQ2;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   08-MAY-2019, entry version 25.
DE   RecName: Full=Chondroitin sulfate ABC lyase {ECO:0000256|PIRNR:PIRNR034515};
DE   AltName: Full=Chondroitin ABC eliminase {ECO:0000256|PIRNR:PIRNR034515};
DE   AltName: Full=Chondroitin ABC lyase {ECO:0000256|PIRNR:PIRNR034515};
DE   AltName: Full=Chondroitinase ABC {ECO:0000256|PIRNR:PIRNR034515};
DE   Flags: Precursor;
GN   OrderedLocusNames=YPA_0445 {ECO:0000313|EMBL:ABG12413.1};
OS   Yersinia pestis bv. Antiqua (strain Antiqua).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=360102 {ECO:0000313|EMBL:ABG12413.1, ECO:0000313|Proteomes:UP000001971};
RN   [1] {ECO:0000313|EMBL:ABG12413.1, ECO:0000313|Proteomes:UP000001971}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Antiqua {ECO:0000313|EMBL:ABG12413.1,
RC   ECO:0000313|Proteomes:UP000001971};
RX   PubMed=16740952; DOI=10.1128/JB.00124-06;
RA   Chain P.S., Hu P., Malfatti S.A., Radnedge L., Larimer F.,
RA   Vergez L.M., Worsham P., Chu M.C., Andersen G.L.;
RT   "Complete genome sequence of Yersinia pestis strains Antiqua and
RT   Nepal516: evidence of gene reduction in an emerging pathogen.";
RL   J. Bacteriol. 188:4453-4463(2006).
CC   -!- FUNCTION: Broad-specificity glycosaminoglycan lyase.
CC       {ECO:0000256|PIRNR:PIRNR034515}.
CC   -!- SIMILARITY: Belongs to the polysaccharide lyase 8 family.
CC       {ECO:0000256|PIRNR:PIRNR034515}.
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DR   EMBL; CP000308; ABG12413.1; -; Genomic_DNA.
DR   RefSeq; WP_002214081.1; NZ_CP009906.1.
DR   EnsemblBacteria; ABG12413; ABG12413; YPA_0445.
DR   EnsemblBacteria; AJJ80768; AJJ80768; CH58_3292.
DR   KEGG; ypa:YPA_0445; -.
DR   PATRIC; fig|360102.15.peg.3461; -.
DR   KO; K08961; -.
DR   OMA; QNAHYEY; -.
DR   BioCyc; YPES360102:GHZU-466-MONOMER; -.
DR   Proteomes; UP000001971; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0034000; F:chondroitin-sulfate-ABC endolyase activity; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006027; P:glycosaminoglycan catabolic process; IEA:InterPro.
DR   Gene3D; 1.50.10.100; -; 1.
DR   Gene3D; 2.60.220.10; -; 1.
DR   Gene3D; 2.70.98.10; -; 1.
DR   InterPro; IPR039174; Chondroitin_ABC_lyase.
DR   InterPro; IPR008929; Chondroitin_lyas.
DR   InterPro; IPR024200; Chondroitinase_ABC_I.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR014718; GH-type_carb-bd.
DR   InterPro; IPR011071; Lyase_8-like_C.
DR   InterPro; IPR004103; Lyase_8_C.
DR   InterPro; IPR003159; Lyase_8_central_dom.
DR   InterPro; IPR015177; Lyase_catalyt.
DR   InterPro; IPR015176; Lyase_N.
DR   PANTHER; PTHR37322; PTHR37322; 1.
DR   Pfam; PF02278; Lyase_8; 1.
DR   Pfam; PF02884; Lyase_8_C; 1.
DR   Pfam; PF09093; Lyase_catalyt; 1.
DR   Pfam; PF09092; Lyase_N; 1.
DR   PIRSF; PIRSF034515; Chondroitinase; 1.
DR   SUPFAM; SSF48230; SSF48230; 1.
DR   SUPFAM; SSF49785; SSF49785; 1.
DR   SUPFAM; SSF49863; SSF49863; 1.
DR   SUPFAM; SSF74650; SSF74650; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0A0E1NZQ2.
DR   SWISS-2DPAGE; A0A0E1NZQ2.
KW   Carbohydrate metabolism {ECO:0000256|PIRNR:PIRNR034515};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001971};
KW   Lyase {ECO:0000256|PIRNR:PIRNR034515}.
SQ   SEQUENCE   1037 AA;  115097 MW;  7018DFFA87388C04 CRC64;
     MYAPSRLKLI ALTMTTLLGT AAYTPHLSAN NTKSAKTEVS QKALMQSSII DFDGNQLPDF
     VTASSGSTLS LSSTRYIMGQ QSLKWEWQAG STMTIEHPIT LVTDKVASKT WGRKATQVLS
     FWIYNETPVD DYMIVDLGRG LGPSGAPDAG IKVKMNFSGW RTVGVSLQND LEGREIEGIG
     FDDNAEGESG GRSTIAGGAK SDMDSIRFRA PLKAPAGIFY IDRVMLSIDD ARYQWSDDHV
     KTRYQIPEIN FRLPAKLPAP TAGEIAAADD IRGALIRVFT EGQGGENGLV VVDNREKLRA
     HFAALKIQRD ADGQLSGRHI ITDKQKVLYQ PEFMDDIDQQ RFSDYVLLGD YTTLMFNISR
     AYQRSTSEEV RQELADMYIL MTQHLLDQGY MDGSGLVTTH HWGYSSRWWY ISAMLMANEL
     DKHQLRQPVS DALLWYSREF KANFDMVPGP ESSDLDYFNT LSRQHLALLM LESDPAKRVA
     LLKRFGEYIN VALSQTPPGG YDGLRPDGTA WRHEGNYPGY SFPAFKNAGQ LVYMLHGTPF
     AVSDEGRAAL KKAMLSAWVY SNPATSLGLA GRHPFNSSSV TLFQDAFRWL ALTGDPKTGD
     KVDKALAAAY LQITETPESE SEAIFGVRIA PAELPQGNWT FNGGAFGIHR FSDKMVTLKA
     YNSNVWSSEI YYRDNRYGRY QSHGAIQVLP YGNQKEIGFV QDGWDWNRNP GTTTIHLPLA
     ELDSPNTHTL MLRGNHPFSG HSSLSGKYGM FAFKFDAPSM PKFDSSFTAR KSALETENRL
     VLLGSNISNN TEKYATETTL FQHGITDKAS DLWVNGERIT ALPYQRALEE GDWLIDGHGN
     GYLLTKGAKG EVRRQHQVSA NDKSRDPTEG NFSLAWLDHG AKPQNAQYEY LMVLEATPEG
     MQQLATDYRA GKKVYEVLRQ DASAHIVRDN VTQTTGYAAF SSVTPDEGVV KNIAQPAIVM
     TQMQSHGQLK ISGVTPDLNM TRTTKATPLA IAVTLNGQWQ ATENNPQVSV KLAGETTQLV
     FTSYFGMPQE VTLKPMN
//

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