(data stored in ACNUC9543 zone)

SWISSPROT: LPLT_YERPA

ID   LPLT_YERPA              Reviewed;         406 AA.
AC   Q1CAS7;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2006, sequence version 1.
DT   08-MAY-2019, entry version 61.
DE   RecName: Full=Lysophospholipid transporter LplT {ECO:0000255|HAMAP-Rule:MF_01585};
GN   Name=lplT {ECO:0000255|HAMAP-Rule:MF_01585};
GN   OrderedLocusNames=YPA_0477;
OS   Yersinia pestis bv. Antiqua (strain Antiqua).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=360102;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Antiqua;
RX   PubMed=16740952; DOI=10.1128/JB.00124-06;
RA   Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F.,
RA   Vergez L.M., Worsham P., Chu M.C., Andersen G.L.;
RT   "Complete genome sequence of Yersinia pestis strains Antiqua and
RT   Nepal516: evidence of gene reduction in an emerging pathogen.";
RL   J. Bacteriol. 188:4453-4463(2006).
CC   -!- FUNCTION: Catalyzes the facilitated diffusion of 2-acyl-glycero-3-
CC       phosphoethanolamine (2-acyl-GPE) into the cell.
CC       {ECO:0000255|HAMAP-Rule:MF_01585}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01585}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01585}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. LplT (TC
CC       2.A.1.42) family. {ECO:0000255|HAMAP-Rule:MF_01585}.
DR   EMBL; CP000308; ABG12445.1; -; Genomic_DNA.
DR   RefSeq; WP_002209842.1; NZ_CP009906.1.
DR   EnsemblBacteria; ABG12445; ABG12445; YPA_0477.
DR   KEGG; ypa:YPA_0477; -.
DR   HOGENOM; HOG000261823; -.
DR   KO; K08227; -.
DR   OMA; CMPAGVL; -.
DR   Proteomes; UP000001971; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0051978; F:lysophospholipid transporter activity; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06174; MFS; 1.
DR   HAMAP; MF_01585; MFS_LplT; 1.
DR   InterPro; IPR023727; LysoPLipid__transptr_LplT.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q1CAS7.
DR   SWISS-2DPAGE; Q1CAS7.
KW   Cell inner membrane; Cell membrane; Complete proteome;
KW   Lipid transport; Membrane; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN         1    406       Lysophospholipid transporter LplT.
FT                                /FTId=PRO_0000309841.
FT   TRANSMEM     16     36       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01585}.
FT   TRANSMEM     53     73       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01585}.
FT   TRANSMEM     91    111       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01585}.
FT   TRANSMEM    139    159       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01585}.
FT   TRANSMEM    164    184       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01585}.
FT   TRANSMEM    227    247       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01585}.
FT   TRANSMEM    253    273       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01585}.
FT   TRANSMEM    285    305       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01585}.
FT   TRANSMEM    310    330       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01585}.
FT   TRANSMEM    349    369       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01585}.
FT   TRANSMEM    372    392       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01585}.
SQ   SEQUENCE   406 AA;  42841 MW;  75DC17EBEC1D1FDE CRC64;
     MSQDVLADKP LLSRSMVAVL CAQFFSAFGD NALLFATLAL IKQQLYPDWS QPILQMAFVA
     TYIVLAPFVG QIADGFAKGR VMMVANGLKL AGALVICFGL NPFLGYSLVG VGAAAYSPAK
     YGILGEITSG EQLVKANGMM EASTIAAILL GSVAGGILAD WHLMAALGVC ALVYAIAVIA
     NLFIPRLAAA RSGASWRPRA MTGSFFTACR LLWQDSETRF SLAGTSLFWG AGVTLRFLLV
     LWVPVALGIA DNATPTLLNA MVAIGIVVGA GAAARFVTLK TVKRCLPAGV LIGVMVTIFS
     LQNSMPMAYL LLIIIGILGG FFVVPLNALL QERGKHSVGA GNAIAVQNLG ENTAMLFMLG
     LYSLVVKLGA PVVAVGVGFG VVFALAIALL WGWQWRQQRQ KTRQPE
//

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