(data stored in ACNUC7421 zone)

SWISSPROT: TAUB_ECOL5

ID   TAUB_ECOL5              Reviewed;         255 AA.
AC   Q0TKS1;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   11-DEC-2019, entry version 93.
DE   RecName: Full=Taurine import ATP-binding protein TauB {ECO:0000255|HAMAP-Rule:MF_01714};
DE            EC=7.6.2.7 {ECO:0000255|HAMAP-Rule:MF_01714};
GN   Name=tauB {ECO:0000255|HAMAP-Rule:MF_01714}; OrderedLocusNames=ECP_0429;
OS   Escherichia coli O6:K15:H31 (strain 536 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=362663;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=536 / UPEC;
RX   PubMed=16879640; DOI=10.1111/j.1365-2958.2006.05255.x;
RA   Hochhut B., Wilde C., Balling G., Middendorf B., Dobrindt U.,
RA   Brzuszkiewicz E., Gottschalk G., Carniel E., Hacker J.;
RT   "Role of pathogenicity island-associated integrases in the genome
RT   plasticity of uropathogenic Escherichia coli strain 536.";
RL   Mol. Microbiol. 61:584-595(2006).
CC   -!- FUNCTION: Part of the ABC transporter complex TauABC involved in
CC       taurine import. Responsible for energy coupling to the transport
CC       system. {ECO:0000255|HAMAP-Rule:MF_01714}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O + taurine(out) = ADP + H(+) + phosphate +
CC         taurine(in); Xref=Rhea:RHEA:14613, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:456216, ChEBI:CHEBI:507393; EC=7.6.2.7;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01714};
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (TauB),
CC       two transmembrane proteins (TauC) and a solute-binding protein (TauA).
CC       {ECO:0000255|HAMAP-Rule:MF_01714}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01714}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01714}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Taurine
CC       importer (TC 3.A.1.17.1) family. {ECO:0000255|HAMAP-Rule:MF_01714}.
DR   EMBL; CP000247; ABG68460.1; -; Genomic_DNA.
DR   RefSeq; WP_000939359.1; NC_008253.1.
DR   SMR; Q0TKS1; -.
DR   EnsemblBacteria; ABG68460; ABG68460; ECP_0429.
DR   KEGG; ecp:ECP_0429; -.
DR   eggNOG; ENOG4108IY8; Bacteria.
DR   eggNOG; COG4525; LUCA.
DR   KO; K10831; -.
DR   OMA; SRNGHEI; -.
DR   BioCyc; ECOL362663:G1G5S-449-MONOMER; -.
DR   Proteomes; UP000009182; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATPase activity; IEA:InterPro.
DR   GO; GO:0015411; F:ATPase-coupled taurine transporter activity; IEA:UniProtKB-UniRule.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like.
DR   InterPro; IPR017871; ABC_transporter_CS.
DR   InterPro; IPR015859; ABC_transpr_TauD.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51250; TAUB; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q0TKS1.
DR   SWISS-2DPAGE; Q0TKS1.
KW   ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW   Nucleotide-binding; Translocase; Transport.
FT   CHAIN           1..255
FT                   /note="Taurine import ATP-binding protein TauB"
FT                   /id="PRO_0000275830"
FT   DOMAIN          2..229
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01714"
FT   NP_BIND         34..41
FT                   /note="ATP"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01714"
SQ   SEQUENCE   255 AA;  28179 MW;  A020E6F1EE739B3C CRC64;
     MLQISHLYAD YGGKPALEDI NLTLESGELL VVLGPSGCGK TTLLNLIAGF VPYQHGSIQL
     AGKGIQGPGA ERGVVFQNEG LLPWRNVQDN VAFGLQLAGV EKMQRLEIAH QMVKKVGLEG
     AEKRYIWQLS GGQRQRVGIA RALAANPQLL LLDEPFGALD AFTRDQMQTL LLKLWQETGK
     QVLLITHDIE EAVFMATELV LLSPGPGRVL ERLPLNFARR FVAGESSRSI KSDPQFIAMR
     EYVLSRVFEQ REAFS
//

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