(data stored in ACNUC7421 zone)

SWISSPROT: DCTA1_PSEAB

ID   DCTA1_PSEAB             Reviewed;         449 AA.
AC   Q02UV9;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   14-NOV-2006, sequence version 1.
DT   05-JUL-2017, entry version 67.
DE   RecName: Full=C4-dicarboxylate transport protein 1 {ECO:0000255|HAMAP-Rule:MF_01300};
GN   Name=dctA1 {ECO:0000255|HAMAP-Rule:MF_01300};
GN   OrderedLocusNames=PA14_01460;
OS   Pseudomonas aeruginosa (strain UCBPP-PA14).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCBPP-PA14;
RX   PubMed=17038190; DOI=10.1186/gb-2006-7-10-r90;
RA   Lee D.G., Urbach J.M., Wu G., Liberati N.T., Feinbaum R.L., Miyata S.,
RA   Diggins L.T., He J., Saucier M., Deziel E., Friedman L., Li L.,
RA   Grills G., Montgomery K., Kucherlapati R., Rahme L.G., Ausubel F.M.;
RT   "Genomic analysis reveals that Pseudomonas aeruginosa virulence is
RT   combinatorial.";
RL   Genome Biol. 7:R90.1-R90.14(2006).
CC   -!- FUNCTION: Responsible for the transport of dicarboxylates such as
CC       succinate, fumarate, and malate from the periplasm across the
CC       membrane. {ECO:0000255|HAMAP-Rule:MF_01300}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01300}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01300}.
CC   -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation
CC       symporter (DAACS) (TC 2.A.23) family. {ECO:0000255|HAMAP-
CC       Rule:MF_01300}.
DR   EMBL; CP000438; ABJ15076.1; -; Genomic_DNA.
DR   RefSeq; WP_003137006.1; NC_008463.1.
DR   ProteinModelPortal; Q02UV9; -.
DR   EnsemblBacteria; ABJ15076; ABJ15076; PA14_01460.
DR   KEGG; pau:PA14_01460; -.
DR   HOGENOM; HOG000208775; -.
DR   KO; K11103; -.
DR   OMA; VDWFMGI; -.
DR   Proteomes; UP000000653; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006835; P:dicarboxylic acid transport; IEA:InterPro.
DR   Gene3D; 1.10.3860.10; -; 1.
DR   HAMAP; MF_01300; C4_dicarb_transport; 1.
DR   InterPro; IPR023954; C4_dicarb_transport.
DR   InterPro; IPR001991; Na-dicarboxylate_symporter.
DR   InterPro; IPR018107; Na-dicarboxylate_symporter_CS.
DR   Pfam; PF00375; SDF; 1.
DR   PRINTS; PR00173; EDTRNSPORT.
DR   SUPFAM; SSF118215; SSF118215; 1.
DR   PROSITE; PS00714; NA_DICARBOXYL_SYMP_2; 1.
PE   3: Inferred from homology;
DR   PRODOM; Q02UV9.
DR   SWISS-2DPAGE; Q02UV9.
KW   Cell inner membrane; Cell membrane; Complete proteome; Membrane;
KW   Symport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN         1    449       C4-dicarboxylate transport protein 1.
FT                                /FTId=PRO_0000321992.
FT   TRANSMEM     14     34       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01300}.
FT   TRANSMEM     47     67       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01300}.
FT   TRANSMEM     83    103       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01300}.
FT   TRANSMEM    157    177       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01300}.
FT   TRANSMEM    195    215       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01300}.
FT   TRANSMEM    226    246       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01300}.
FT   TRANSMEM    312    332       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01300}.
FT   TRANSMEM    359    379       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01300}.
FT   TRANSMEM    385    405       Helical. {ECO:0000255|HAMAP-
FT                                Rule:MF_01300}.
SQ   SEQUENCE   449 AA;  47414 MW;  9B6C06DEC21939BD CRC64;
     METPAMFIKR CSRSIFLQVV IGLVIGVICG VGIPDLAVQM KPLGDGFIKL IKMLIALIVF
     CVVVNGISGA GDLKKVGRIG LKSVIYFEIL TTIALVLGLV VAYSLGLGSG ANIHLNELPA
     GDVALYTGRT QEIHGPVAFL MGLIPTSVFS AFAENDILQV LLFSVLFGSA LNLVGEQASG
     VARLINEFSH IVFRIMGMIV RLAPLGVFGA VAFTTARYGV DSLSHLGALV LVFYATCLVF
     VMAVLGSVLR LSGVRMLPFL RYFREELMIV MGTASSDAVL PQVMRKLEHM GIRSSTVGLV
     IPTGYSFNLD GFSIYLTLAV VFIAHVTGTP LAMTDLVTIL LVSLVTSKGA HGIPGSALVI
     LAATLTAVPA IPVAGLVLVL SVDWFMGIGR ALTNLIGNCV ATVTIARWEN DIDMPRAQAI
     LDGRLEAPAK ADGEPLKRSA VAGEGKLHG
//

If you have problems or comments...

PBIL Back to PBIL home page