(data stored in ACNUC7421 zone)

SWISSPROT: A0A0H2ZKX2_PSEAB

ID   A0A0H2ZKX2_PSEAB        Unreviewed;       240 AA.
AC   A0A0H2ZKX2;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   07-JUN-2017, entry version 10.
DE   RecName: Full=Ribosomal RNA small subunit methyltransferase E {ECO:0000256|PIRNR:PIRNR015601};
DE            EC=2.1.1.193 {ECO:0000256|PIRNR:PIRNR015601};
GN   OrderedLocusNames=PA14_05450 {ECO:0000313|EMBL:ABJ15386.1};
OS   Pseudomonas aeruginosa (strain UCBPP-PA14).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208963 {ECO:0000313|EMBL:ABJ15386.1, ECO:0000313|Proteomes:UP000000653};
RN   [1] {ECO:0000313|EMBL:ABJ15386.1, ECO:0000313|Proteomes:UP000000653}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCBPP-PA14 {ECO:0000313|EMBL:ABJ15386.1,
RC   ECO:0000313|Proteomes:UP000000653};
RX   PubMed=17038190; DOI=10.1186/gb-2006-7-10-r90;
RA   Lee D.G., Urbach J.M., Wu G., Liberati N.T., Feinbaum R.L., Miyata S.,
RA   Diggins L.T., He J., Saucier M., Deziel E., Friedman L., Li L.,
RA   Grills G., Montgomery K., Kucherlapati R., Rahme L.G., Ausubel F.M.;
RT   "Genomic analysis reveals that Pseudomonas aeruginosa virulence is
RT   combinatorial.";
RL   Genome Biol. 7:R90.1-R90.14(2006).
CC   -!- FUNCTION: Specifically methylates the N3 position of the uracil
CC       ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully
CC       assembled 30S ribosomal subunit. {ECO:0000256|PIRNR:PIRNR015601}.
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + uracil(1498) in 16S
CC       rRNA = S-adenosyl-L-homocysteine + N(3)-methyluracil(1498) in 16S
CC       rRNA. {ECO:0000256|PIRNR:PIRNR015601}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|PIRNR:PIRNR015601}.
CC   -!- SIMILARITY: Belongs to the RNA methyltransferase RsmE family.
CC       {ECO:0000256|PIRNR:PIRNR015601}.
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DR   EMBL; CP000438; ABJ15386.1; -; Genomic_DNA.
DR   RefSeq; WP_011666535.1; NC_008463.1.
DR   ProteinModelPortal; A0A0H2ZKX2; -.
DR   EnsemblBacteria; ABJ15386; ABJ15386; PA14_05450.
DR   KEGG; pau:PA14_05450; -.
DR   KO; K09761; -.
DR   OMA; ERMEFTI; -.
DR   Proteomes; UP000000653; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.1280.10; -; 1.
DR   InterPro; IPR029028; Alpha/beta_knot_MTases.
DR   InterPro; IPR015947; PUA-like_domain.
DR   InterPro; IPR006700; rRNA_ssu_MeTrfase-E.
DR   InterPro; IPR029026; tRNA_m1G_MTases_N.
DR   PANTHER; PTHR30027; PTHR30027; 1.
DR   Pfam; PF04452; Methyltrans_RNA; 1.
DR   PIRSF; PIRSF015601; MTase_slr0722; 1.
DR   SUPFAM; SSF75217; SSF75217; 1.
DR   SUPFAM; SSF88697; SSF88697; 1.
DR   TIGRFAMs; TIGR00046; TIGR00046; 1.
PE   3: Inferred from homology;
DR   PRODOM; A0A0H2ZKX2.
DR   SWISS-2DPAGE; A0A0H2ZKX2.
KW   Complete proteome {ECO:0000313|Proteomes:UP000000653};
KW   Cytoplasm {ECO:0000256|PIRNR:PIRNR015601};
KW   Methyltransferase {ECO:0000256|PIRNR:PIRNR015601};
KW   rRNA processing {ECO:0000256|PIRNR:PIRNR015601};
KW   S-adenosyl-L-methionine {ECO:0000256|PIRNR:PIRNR015601};
KW   Transferase {ECO:0000256|PIRNR:PIRNR015601}.
SQ   SEQUENCE   240 AA;  26507 MW;  0CD53FAAD4E6C392 CRC64;
     MRLSRFFVDQ PLALGQHDLP ETQAHYIGRV LRHATGDAVQ LFDGSGREYL GELVEVGKKN
     VRVELREQFA GQPDSPLRIH LGQGLSRGER MDWAIQKATE LGVAEITPIV SERCEVRLKD
     ERADKRLQHW RQVAISACEQ CGRSSLPLIH PPLALEDWLR GRDDELRLVL HPVAAPLASH
     VPPSRLAFLV GPKGGLSDAE VEQAKAAGFH AARLGPRVLR TETAPVVALA VAQQLWGDFA
//

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