(data stored in ACNUC7421 zone)

SWISSPROT: A0A0H2ZLB8_PSEAB

ID   A0A0H2ZLB8_PSEAB        Unreviewed;       797 AA.
AC   A0A0H2ZLB8;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   07-JUN-2017, entry version 15.
DE   SubName: Full=Putative histidine kinase {ECO:0000313|EMBL:ABJ15564.1};
GN   OrderedLocusNames=PA14_07820 {ECO:0000313|EMBL:ABJ15564.1};
OS   Pseudomonas aeruginosa (strain UCBPP-PA14).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208963 {ECO:0000313|EMBL:ABJ15564.1, ECO:0000313|Proteomes:UP000000653};
RN   [1] {ECO:0000313|EMBL:ABJ15564.1, ECO:0000313|Proteomes:UP000000653}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UCBPP-PA14 {ECO:0000313|EMBL:ABJ15564.1,
RC   ECO:0000313|Proteomes:UP000000653};
RX   PubMed=17038190; DOI=10.1186/gb-2006-7-10-r90;
RA   Lee D.G., Urbach J.M., Wu G., Liberati N.T., Feinbaum R.L., Miyata S.,
RA   Diggins L.T., He J., Saucier M., Deziel E., Friedman L., Li L.,
RA   Grills G., Montgomery K., Kucherlapati R., Rahme L.G., Ausubel F.M.;
RT   "Genomic analysis reveals that Pseudomonas aeruginosa virulence is
RT   combinatorial.";
RL   Genome Biol. 7:R90.1-R90.14(2006).
CC   -!- CATALYTIC ACTIVITY: ATP + protein L-histidine = ADP + protein N-
CC       phospho-L-histidine. {ECO:0000256|SAAS:SAAS00414205}.
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DR   EMBL; CP000438; ABJ15564.1; -; Genomic_DNA.
DR   RefSeq; WP_003137372.1; NC_008463.1.
DR   ProteinModelPortal; A0A0H2ZLB8; -.
DR   EnsemblBacteria; ABJ15564; ABJ15564; PA14_07820.
DR   KEGG; pau:PA14_07820; -.
DR   OMA; ILWVNWD; -.
DR   Proteomes; UP000000653; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:InterPro.
DR   GO; GO:0005622; C:intracellular; IEA:GOC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   CDD; cd00130; PAS; 2.
DR   Gene3D; 3.30.565.10; -; 1.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR013655; PAS_fold_3.
DR   InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR   InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR   InterPro; IPR001638; Solute-binding_3/MltF_N.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF07730; HisKA_3; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   Pfam; PF00497; SBP_bac_3; 1.
DR   PRINTS; PR00344; BCTRLSENSOR.
DR   SMART; SM00387; HATPase_c; 1.
DR   SMART; SM00086; PAC; 2.
DR   SMART; SM00091; PAS; 2.
DR   SMART; SM00062; PBPb; 1.
DR   SUPFAM; SSF55785; SSF55785; 2.
DR   SUPFAM; SSF55874; SSF55874; 1.
DR   TIGRFAMs; TIGR00229; sensory_box; 2.
DR   PROSITE; PS50109; HIS_KIN; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
DR   PRODOM; A0A0H2ZLB8.
DR   SWISS-2DPAGE; A0A0H2ZLB8.
KW   ATP-binding {ECO:0000256|SAAS:SAAS00776324};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000653};
KW   Kinase {ECO:0000256|SAAS:SAAS00494113, ECO:0000313|EMBL:ABJ15564.1};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS00777800};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transferase {ECO:0000256|SAAS:SAAS00494184}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    797       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002603826.
FT   DOMAIN      395    445       PAC (PAS-associated C-terminal).
FT                                {ECO:0000259|PROSITE:PS50113}.
FT   DOMAIN      446    523       PAS (PER-ARNT-SIM). {ECO:0000259|PROSITE:
FT                                PS50112}.
FT   DOMAIN      599    794       Histidine kinase. {ECO:0000259|PROSITE:
FT                                PS50109}.
FT   COILED      568    595       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   797 AA;  89506 MW;  11D0857ABC73C682 CRC64;
     MLRRCCLLFF CLLLSLPVRA EESVALPLTA ELRTWLAEHR ELRVGVVTEA PYAQYDRRLQ
     QYSGANVELM GWLATAMQVT LRWQGYPDQA ALDDALRAGR VDIAPGLSQT PAGLRLWLFS
     DPYLRVSRLV VGKRDGSGSV ELEQLERDTR VAVRAGSSVA DYLSSTYSSL QWVSADSERE
     VLRAVLAGQA RYAVIDEAQL SRLTREPEFA ELAVVGDIGY PQLLRVATRR DWPELAMVVD
     QALRSLPRKS LDQLHERWLQ PKYPRLGESP GFWQNLSILL GLLLAGALAA VFLQRRQQHA
     LEARLYGARR DLELRQAAEE ALRLTQFSID NSTLGILWVN WDSRVRYANR AAEQMLGHAD
     GQLVDRPLAD FEPGLDMDRW LNLWRRARNS EEGPLSFETR CLRADGSWLP ADVSLSFLRF
     GTSEYLVVFL SDVTERRRAR EALQESEARM KGIASNVPGM VFRLERPRAG AFSDFAYISE
     GSEALVGYSA LELIESGRGI RGLVHPDDRE RYWSSQMAAL DENRDWHWQG RILTRQGELR
     WADIKASARC FEDGRAVWDG VVWDITANKQ IELELGESRA QLRELSAHLE SVREEEKARI
     AREVHDELGQ VLTVLKLETS MCELAYADAQ EGLRERLGNM KKLIAQLFQL VRDVATALRP
     PILDAGIGSA VEWQARRFEA RTQIPCLVEV PENSPQLVDA KAIGLFRILQ EALTNVMRHA
     EAHTVQLRLL REGDELCLSV SDDGRGFDVA TVGRGSSFGL VGMRERVLMM GGTLDIDSAP
     GEGTTLSVRI PLGVASP
//

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